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of 4
pro vyhledávání: '"Mary Margaret Gozar"'
Autor:
Mary Margaret Gozar, Craig Witherington, Toby Passioura, Angela Lai, Laurent P. Rivory, Amber Goodchild, Andrew King
Publikováno v:
Oligonucleotides. 18(3)
We have previously shown that Dz13, a catalytic DNA molecule (DNAzyme) designed against c-jun, is cytotoxic to nonquiescent cells by a mechanism independent of c-jun mRNA cleavage. In this report, we evaluated programmed cell death (PCD) pathways in
Autor:
Laurent P. Rivory, Amber Goodchild, Andrew King, Angela Lai, Donald J. Birkett, Craig Witherington, Carly Tucker, Mary Margaret Gozar
Publikováno v:
Oligonucleotides. 16(4)
DNAzymes are catalytic DNA molecules capable of cleaving RNA substrates and therefore constitute a possible gene-suppression technology. We examined whether the previously reported potency of a DNAzyme targeting c-jun (Dz13) could be improved with ju
Autor:
Andrew King, Amber Goodchild, Laurent P. Rivory, Toby Passioura, Greg M. Arndt, Michael Poidinger, Donald J. Birkett, Mary Margaret Gozar
Publikováno v:
BMC Biotechnology, Vol 9, Iss 1, p 57 (2009)
BMC Biotechnology
BMC Biotechnology
Background Short interfering RNAs (siRNAs) have become the research tool of choice for gene suppression, with human clinical trials ongoing. The emphasis so far in siRNA therapeutics has been the design of one siRNA with complete complementarity to t
Autor:
Laurent Rivory, Carly Tucker, Andrew King, Angela Lai, Amber Goodchild, Craig Witherington, Mary Margaret Gozar, Donald J. Birkett
Publikováno v:
Oligonucleotides; Vol. 16 Issue 4, p297-312, 16p