Zobrazeno 1 - 10
of 156
pro vyhledávání: '"Mary M. Stevenson"'
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Infection with helminths or parasitic worms are highly prevalent worldwide especially in developing regions. Helminths cause chronic infections that are associated with suppression of immune responses to unrelated pathogens, vaccines, and by-stander
Externí odkaz:
https://doaj.org/article/6e63436db51141fa86f1e89d0e25e427
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Control and elimination of blood-stage Plasmodium chabaudi AS infection requires CD4+ Th1 cells that secrete IFN-γ and T follicular help (Tfh) cells together with B cell production of antibody. Foxp3+ regulatory T cells (Tregs) are also crucial to p
Externí odkaz:
https://doaj.org/article/ca141eb047be4a2882e0dbe40a5bf279
Publikováno v:
International Journal of Biological Sciences, Vol 7, Iss 9, Pp 1311-1322 (2011)
Although a clearer understanding of the underlying mechanisms involved in protection and immunopathology during blood-stage malaria has emerged, the mechanisms involved in regulating the adaptive immune response especially those required to maintain
Externí odkaz:
https://doaj.org/article/c470c9da17fb405eb52fc6df2527728f
Publikováno v:
Haematologica, Vol 94, Iss 2 (2009)
Background The contribution of pro-inflammatory cytokines to the pathogenesis of malarial anemia has been studied extensively but the roles of Th2 cytokines remain unknown. Here, we investigated the role of signal transducer and activator of transcri
Externí odkaz:
https://doaj.org/article/a410a2f16a54461bbea68ee13f100794
Autor:
Nathalia L. Malacco, Aubrey N. Michi, Elizabeth Siciliani, Ana G. Madrigal, Tamara Sternlieb, Ghislaine Fontes, Irah L. King, Igor Cestari, Armando Jardim, Mary M. Stevenson, Fernando Lopes
Inflammatory bowel diseases (IBD) are chronic inflammatory diseases in which abdominal pain, bloody diarrhea, weight loss, and fatigue collectively result in diminished quality of patient life. The disappearance of intestinal helminth infections in W
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1428504706424c5266e97cbc92732f81
https://doi.org/10.1101/2023.01.26.525718
https://doi.org/10.1101/2023.01.26.525718
Autor:
Armando Jardim, Timothy G. Geary, Louis-Philippe Leroux, E A Siciliani, T Arai, Mary M. Stevenson, Fernando Lopes
Publikováno v:
J Can Assoc Gastroenterol
Background Parasitic helminths Trichuris suis and Ascaris suum are known to modulate host immune responses. This is thought to be mediated by the secretome, or excreted factors released by these parasites. We are interested in the excretory/secretory
Autor:
Rajesh M. Valanparambil, Armando Jardim, Elizabeth Siciliani, Dante S. Zarlenga, Timothy G. Geary, Louis-Philippe Leroux, Maritza Jaramillo, Mifong Tam, Dolores E. Hill, Makedonka Mitreva, Mohamad Nasr, Joel V. Weinstock, Joseph F. Urban, Mary M. Stevenson, Bruce A. Rosa
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-17 (2018)
Scientific Reports
Scientific Reports, Nature Publishing Group, 2018, 8 (1), pp.15921. ⟨10.1038/s41598-018-34174-4⟩
Scientific Reports
Scientific Reports, Nature Publishing Group, 2018, 8 (1), pp.15921. ⟨10.1038/s41598-018-34174-4⟩
Parasitic worms have a remarkable ability to modulate host immune responses through several mechanisms including excreted/secreted proteins (ESP), yet the exact nature of these proteins and their targets often remains elusive. Here, we performed mass
Autor:
Mary M. Stevenson, Hakeem Sam
Publikováno v:
McGill Journal of Medicine, Vol 1, Iss 1 (2020)
In this study, we investigated host response to Bacillus-Calmette Guérin (BCG) immunotherapy using the murine MM45T bladder tumor cell line. BALB/c (Bcgs allele) and BALB/c.CD2 (CD2) (Bcgr allele) mice were seeded subcutaneously with MM45T cells. Tr
Publikováno v:
Mucosal Immunology. 10:238-249
Primary infection with the gastrointestinal nematode Heligmosomoides polygyrus bakeri is chronic in C57BL/6 (B6) mice whereas challenge infection is rapidly eliminated. F4/80-CD11b+Gr+ cells, presumed to be neutrophils, were reported to accumulate ar
Autor:
Timothy G. Geary, Joseph F. Urban, Arthur M. Blum, Makedonka Mitreva, Long Hang, Mary M. Stevenson, Sangeeta Kumar, Armando Jardim, Joel V. Weinstock, Clifford A. Lowell
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950), vol 197, iss 7
Helminthic infections modulate host immunity and may protect people in less-developed countries from developing immunological diseases. In a murine colitis model, the helminth Heligmosomoides polygyrus bakeri prevents colitis via induction of regulat