Zobrazeno 1 - 10
of 147
pro vyhledávání: '"Mary M Stevenson"'
Autor:
Hakeem Sam, Mary M Stevenson
Publikováno v:
McGill Journal of Medicine, Vol 1, Iss 1 (2020)
In this study, we investigated host response to Bacillus-Calmette Guérin (BCG) immunotherapy using the murine MM45T bladder tumor cell line. BALB/c (Bcgs allele) and BALB/c.CD2 (CD2) (Bcgr allele) mice were seeded subcutaneously with MM45T cells. Tr
Externí odkaz:
https://doaj.org/article/f9734bd71106492a9226d01e2b633c09
Autor:
Rajesh M Valanparambil, Mifong Tam, Pierre-Paul Gros, Jean-Philippe Auger, Mariela Segura, Philippe Gros, Armando Jardim, Timothy G Geary, Keiko Ozato, Mary M Stevenson
Publikováno v:
PLoS Pathogens, Vol 13, Iss 10, p e1006647 (2017)
Interferon regulatory factor-8 (IRF-8) is critical for Th1 cell differentiation and negatively regulates myeloid cell development including myeloid-derived suppressor cells (MDSC). MDSC expand during infection with various pathogens including the gas
Externí odkaz:
https://doaj.org/article/7ed5a4d98cc749188793e07309153a83
Publikováno v:
PLoS ONE, Vol 12, Iss 5, p e0177818 (2017)
Pyruvate kinase (PKLR) deficiency protects mice and humans against blood-stage malaria. Although mouse strain AcB62 carries a malaria-protective PklrI90N genetic mutation, it is phenotypically susceptible to blood stage malaria induced by infection w
Externí odkaz:
https://doaj.org/article/380c755e7c4b483abd726df43509b8f3
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 10, Iss 4, p e0004624 (2016)
Helminth infections affect more than a third of the world's population. Despite very broad phylogenetic differences among helminth parasite species, a systemic Th2 host immune response is typically associated with long-term helminth infections, also
Externí odkaz:
https://doaj.org/article/eceec56b626c4ed6b55879553d2ea6d6
Autor:
Joanne Berghout, David Langlais, Irena Radovanovic, Mifong Tam, John D MacMicking, Mary M Stevenson, Philippe Gros
Publikováno v:
PLoS Pathogens, Vol 9, Iss 7, p e1003491 (2013)
Interferon Regulatory Factor 8 (IRF8) is required for development, maturation and expression of anti-microbial defenses of myeloid cells. BXH2 mice harbor a severely hypomorphic allele at Irf8 (Irf8(R294C)) that causes susceptibility to infection wit
Externí odkaz:
https://doaj.org/article/a35d16f33c834cc29282f236061241b1
Autor:
Yovany Moreno, Pierre-Paul Gros, Mifong Tam, Mariela Segura, Rajesh Valanparambil, Timothy G Geary, Mary M Stevenson
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 5, Iss 10, p e1370 (2011)
The murine parasite Heligmosomoides polygyrus is a convenient experimental model to study immune responses and pathology associated with gastrointestinal nematode infections. The excretory-secretory products (ESP) produced by this parasite have poten
Externí odkaz:
https://doaj.org/article/d2dd2957324349eaa0356b94c725796a
Autor:
Nathalia L. Malacco, Aubrey N. Michi, Elizabeth Siciliani, Ana G. Madrigal, Tamara Sternlieb, Ghislaine Fontes, Irah L. King, Igor Cestari, Armando Jardim, Mary M. Stevenson, Fernando Lopes
Inflammatory bowel diseases (IBD) are chronic inflammatory diseases in which abdominal pain, bloody diarrhea, weight loss, and fatigue collectively result in diminished quality of patient life. The disappearance of intestinal helminth infections in W
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1428504706424c5266e97cbc92732f81
https://doi.org/10.1101/2023.01.26.525718
https://doi.org/10.1101/2023.01.26.525718
Publikováno v:
Frontiers in Immunology. 13
Infection with helminths or parasitic worms are highly prevalent worldwide especially in developing regions. Helminths cause chronic infections that are associated with suppression of immune responses to unrelated pathogens, vaccines, and by-stander
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::295e615ae7b14fc14ffef29adc239367
https://doi.org/10.3389/fimmu.2022.874308
https://doi.org/10.3389/fimmu.2022.874308
Autor:
Armando Jardim, Timothy G. Geary, Louis-Philippe Leroux, E A Siciliani, T Arai, Mary M. Stevenson, Fernando Lopes
Publikováno v:
J Can Assoc Gastroenterol
Background Parasitic helminths Trichuris suis and Ascaris suum are known to modulate host immune responses. This is thought to be mediated by the secretome, or excreted factors released by these parasites. We are interested in the excretory/secretory
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aff0402fb3d184d5d8d4d7684ce7432e
https://doi.org/10.1093/jcag/gwab002.050
https://doi.org/10.1093/jcag/gwab002.050
Autor:
Rajesh M. Valanparambil, Armando Jardim, Elizabeth Siciliani, Dante S. Zarlenga, Timothy G. Geary, Louis-Philippe Leroux, Maritza Jaramillo, Mifong Tam, Dolores E. Hill, Makedonka Mitreva, Mohamad Nasr, Joel V. Weinstock, Joseph F. Urban, Mary M. Stevenson, Bruce A. Rosa
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-17 (2018)
Scientific Reports
Scientific Reports, Nature Publishing Group, 2018, 8 (1), pp.15921. ⟨10.1038/s41598-018-34174-4⟩
Scientific Reports
Scientific Reports, Nature Publishing Group, 2018, 8 (1), pp.15921. ⟨10.1038/s41598-018-34174-4⟩
Parasitic worms have a remarkable ability to modulate host immune responses through several mechanisms including excreted/secreted proteins (ESP), yet the exact nature of these proteins and their targets often remains elusive. Here, we performed mass
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67eece5b56715fcbbec9c0b3e6618187
http://link.springer.com/article/10.1038/s41598-018-34174-4
http://link.springer.com/article/10.1038/s41598-018-34174-4