Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Mary M Chen"'
Autor:
Tiffany F. Lin, Gary J. Schiller, Johnnie J. Orozco, Gail J. Roboz, Mohamed M. Hegazi, Laura Finn, Mary M Chen
Publikováno v:
Blood. 140:3336-3337
Background: Resistance to venetoclax, a BCL2 inhibitor, has been shown to be mediated by co-expression of other BCL2 proteins including BCLXL and MCL1 in relapsed/refractory AML (R/R AML). Therapeutic agents reducing resistance to BCL2 inhibitors and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::642c4b3a5532e5e71992c37fa80cd5c2
https://doi.org/10.1182/blood-2022-157588
https://doi.org/10.1182/blood-2022-157588
Autor:
Sameem Abedin, Guru Subramanian Guru Murthy, Aniko Szabo, Mehdi Hamadani, Laura C. Michaelis, Karen-Sue Carlson, Lyndsey Runaas, Katelyn Gauger, Avinash G Desai, Mary M Chen, Alexandra M. Harrington, Ehab L. Atallah
Publikováno v:
Blood. 140:157-158
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d75e01a3e20039d27e57454c999089ad
https://doi.org/10.1182/blood-2022-157827
https://doi.org/10.1182/blood-2022-157827
Autor:
Steve Lacroix, Paul A. Monach, Jerry Ware, Pierre Cunin, Yoichiro Iwakura, Tatiana G. Jones, Peter A. Nigrovic, Joseph E. Italiano, Mary M. Chen, Loka R. Penke, Eric Boilard, Jonathan N. Thon, Michael F. Gurish, Imene Melki, Margaret H. Chang
Publikováno v:
Journal of Clinical Investigation. 127:1714-1724
The growth factor receptor Kit is involved in hematopoietic and nonhematopoietic development. Mice bearing Kit defects lack mast cells; however, strains bearing different Kit alleles exhibit diverse phenotypes. Herein, we investigated factors underly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26223929ab9021497618bbd37620f8f3
https://doi.org/10.1172/jci84598
https://doi.org/10.1172/jci84598
Publikováno v:
Teaching and Learning in Medicine. 28:320-328
The departure of physician-scientists from education and research into clinical practice is a growing challenge for the future of academic medicine. Junior faculty face competing demands for clinical productivity, teaching, research, and work-life in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de2bf4c6fb4ec5352282c22fbea20cea
https://doi.org/10.1080/10401334.2016.1153476
https://doi.org/10.1080/10401334.2016.1153476
Autor:
Paula Marlton, Helen M. Thackray, Daniel J. DeAngelo, Gavin Cull, Brian A. Jonas, Geoffrey L. Uy, Jane L. Liesveld, Harry P. Erba, Anjali S. Advani, Bhavana Bhatnagar, Mary M Chen, Eric J. Feldman, Brenda W. Cooper, William E. Fogler, John L. Magnani, Michael O'Dwyer, Pamela S. Becker, Michael B. Armstrong, Gerwin Huls
Publikováno v:
Blood. 134:2650-2650
Background Binding of E-selectin (E-sel) to sialyl Lex, the E-sel ligand, on the leukemic cell surface activates cell survival pathways and promotes chemotherapy resistance in AML. Higher expression of E-sel ligand is associated with relapse and poor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e30054b491e00fff5508e63695b02998
https://doi.org/10.1182/blood-2019-123816
https://doi.org/10.1182/blood-2019-123816
Autor:
Jane L. Liesveld, William E. Fogler, John L. Magnani, Daniel J. DeAngelo, Pamela S. Becker, Michael O'Dwyer, Helen M. Thackray, Eric J. Feldman, Mary M Chen, Brian A. Jonas, Anjali S. Advani, Dale L. Bixby, Paula Marlton
Publikováno v:
Blood. 134:2690-2690
Leukemic myeloblasts expressing E-selectin ligand (E-sel ligand) adhere to E-selectin on bone marrow endothelium resulting in environment-mediated drug resistance (EMDR). Uproleselan, a potent E-selectin inhibitor, disrupts the adhesion of AML cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::984d5768bc70331fbe6915801f08e48f
https://doi.org/10.1182/blood-2019-123744
https://doi.org/10.1182/blood-2019-123744
Autor:
Thomas Quertermous, Thomas Finsterbach, Michael Y Ho, David Charo, Mary M. Chen, Kavita V Ernst, Ramendra K. Kundu, Euan A. Ashley, Yen-Dong Ho, Masataka Kawana, Ahmad Y. Sheikh, Daniel Bernstein, Giovanni Fajardo, Hyung J. Chun, Nicholas J. Leeper
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 297:H1904-H1913
Studies have shown significant cardiovascular effects of exogenous apelin administration, including the potent activation of cardiac contraction. However, the role of the endogenous apelin-APJ pathway is less clear. To study the loss of endogenous ap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53e84e69cc2a20405fbe583ec261ba5e
https://doi.org/10.1152/ajpheart.00686.2009
https://doi.org/10.1152/ajpheart.00686.2009
Autor:
Ingo Kutschka, Ziad A. Ali, Philip S. Tsao, Stephen L. Hendry, Mary M. Chen, Patrick Yue, Diego Ardigò, Ramendera K. Kundu, Marc P. Pelletier, Hyung J. Chun, Robert C. Robbins, Andrew J. Connolly, Ahmad Y. Sheikh, Alexander J. Glassford, Thomas Quertermous, Roger A. Wagner, Diem T. Huynh
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 294:H88-H98
Signaling by the peptide ligand apelin and its cognate G protein-coupled receptor APJ has a potent inotropic effect on cardiac contractility and modulates systemic vascular resistance through nitric oxide-dependent signaling. In addition, there is ev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c9671a8fbeeadd8d965517a7e4546a4
https://doi.org/10.1152/ajpheart.00935.2007
https://doi.org/10.1152/ajpheart.00935.2007
Publikováno v:
Cancer Epidemiology, Biomarkers & Prevention. 15:424-428
Metabolic markers of bone metabolism may be useful for the diagnosis and monitoring of bone metastasis in breast cancer patients. Serum tartrate-resistant acid phosphatase 5b (TRACP5b) activity is a novel bone resorption marker. The treatment respons
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fbee3eab310e01d6eea0e353d88262f
https://doi.org/10.1158/1055-9965.epi-04-0842
https://doi.org/10.1158/1055-9965.epi-04-0842
Autor:
Tsu-Yi Chao, Jyh-Cherng Yu, Chih-Hung Ku, Mary M. Chen, Su-Huei Lee, Anthony J. Janckila, Lung T. Yam
Publikováno v:
Clinical Cancer Research. 11:544-550
Purpose: Previous studies showed that serum tartrate-resistant acid phosphatase 5b (TRACP5b) activity was increased in 70% to 94% of breast cancer (BC) patients with bone metastasis (BM). This study aims to determine whether serum TRACP5b is useful f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::37ca184dd1f10f7b544324d730c41ca1
https://doi.org/10.1158/1078-0432.544.11.2
https://doi.org/10.1158/1078-0432.544.11.2