Zobrazeno 1 - 10
of 63
pro vyhledávání: '"Mary Lor"'
Autor:
David A. Dworaczyk, PhD, Allen L. Hunt, MD, Mike Di Spirito, MSc, Mary Lor, BSc, GrDip, Kenneth L. Dretchen, PhD, Michael J. Lamson, PhD, Jonathan Pollock, MSci, Thelma Ward, PhD
Publikováno v:
Journal of Allergy and Clinical Immunology: Global, Vol 3, Iss 2, Pp 100200- (2024)
Background: Recent acute anaphylaxis guideline updates have identified remaining unmet needs based on currently available therapeutic options as a critical focus. Objective: We compared the pharmacokinetic, pharmacodynamic, safety, and tolerability p
Externí odkaz:
https://doaj.org/article/2a2ab5a5ea6049e09fa365f1fd167b13
Autor:
Romal Stewart, Kexin Yan, Sevannah A. Ellis, Cameron R. Bishop, Troy Dumenil, Bing Tang, Wilson Nguyen, Thibaut Larcher, Rhys Parry, Julian De Jun Sng, Alexander A. Khromykh, Robert K. P. Sullivan, Mary Lor, Frédéric A. Meunier, Daniel J. Rawle, Andreas Suhrbier
Publikováno v:
Frontiers in Microbiology, Vol 14 (2023)
The reduced pathogenicity of the omicron BA.1 sub-lineage compared to earlier variants is well described, although whether such attenuation is retained for later variants like BA.5 and XBB remains controversial. We show that BA.5 and XBB isolates wer
Externí odkaz:
https://doaj.org/article/e3bb846c283046a5ad1923ef2b19de68
Autor:
Dongsheng Li, Min-Hsuan Lin, Daniel J. Rawle, Hongping Jin, Zhonglan Wu, Lu Wang, Mary Lor, Mazhar Hussain, John Aaskov, David Harrich
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-11 (2021)
Li et al. produce a dengue virus (DENV)-derived defective interfering particle (DIP) production cell line that can stably produce infectious virusfree DIPs. The DENV DIPs produced from this system can potently inhibit replication of all DENV serotype
Externí odkaz:
https://doaj.org/article/ca6d677537e941f587164eee3d3acebc
Autor:
Mahali S. Morgan, Kexin Yan, Thuy T. Le, Ryan A. Johnston, Alberto A. Amarilla, David A. Muller, Christopher L. D. McMillan, Naphak Modhiran, Daniel Watterson, James R. Potter, Julian D.J. Sng, Mary Lor, Devina Paramitha, Ariel Isaacs, Alexander A. Khromykh, Roy A. Hall, Andreas Suhrbier, Daniel J. Rawle, Jody Hobson-Peters
Publikováno v:
Viruses, Vol 15, Iss 1, p 139 (2022)
The global coronavirus disease 2019 (COVID-19) pandemic caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has spawned an ongoing demand for new research reagents and interventions. Herein we describe a panel of monoclonal ant
Externí odkaz:
https://doaj.org/article/82d6e8999d344525a4e59c50bacc8174
Autor:
Natale Snape, Dongsheng Li, Ting Wei, Hongping Jin, Mary Lor, Daniel J. Rawle, Kirsten M. Spann, David Harrich
Publikováno v:
Virology Journal, Vol 15, Iss 1, Pp 1-10 (2018)
Abstract Cellular protein eukaryotic translation elongation factor 1A (eEF1A) is an actin binding protein that plays a role in the formation of filamentous actin (F-actin) bundles. F-Actin regulates multiple stages of respiratory syncytial virus (RSV
Externí odkaz:
https://doaj.org/article/2de9c2c0b44942f5a1b9b9a6bcaaf548
Publikováno v:
mBio, Vol 10, Iss 4 (2019)
ABSTRACT Nullbasic is a mutant form of the HIV-1 transcriptional activator protein (Tat) that strongly inhibits HIV-1 transcription and replication in lymphocytes in vitro. To investigate Nullbasic inhibition in vivo, we employed an NSG mouse model w
Externí odkaz:
https://doaj.org/article/c9a71731e6fa47759ced68c46a9dda02
Autor:
Hongping Jin, Dongsheng Li, Haran Sivakumaran, Mary Lor, Lina Rustanti, Nicole Cloonan, Shivangi Wani, David Harrich
Publikováno v:
mBio, Vol 7, Iss 4 (2016)
ABSTRACT Nullbasic is a derivative of the HIV-1 transactivator of transcription (Tat) protein that strongly inhibits HIV-1 replication in lymphocytes. Here we show that lentiviral vectors that constitutively express a Nullbasic-ZsGreen1 (NB-ZSG1) fus
Externí odkaz:
https://doaj.org/article/84093b2e09a64b72a2773d3f66c2ba85
Autor:
Romal Stewart, Sevannah Ellis, Kexin Yan, Troy Dumenil, Cameron Bishop, Bing Tang, Wilson Nguyen, Thibaut Larcher, Robert Sullivan, Mary Lor, Frederic Meunier, Daniel Rawle, Andreas Suhrbier
The reduced pathogenicity of the omicron BA.1 sub-lineage compared to earlier variants is well described, although whether such attenuation is retained for later variants like BA.5 remains controversial. We show that a BA.5 isolate was significantly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8925c0fdedd0359bfee298fa88a51b47
https://doi.org/10.21203/rs.3.rs-2702556/v1
https://doi.org/10.21203/rs.3.rs-2702556/v1
Publikováno v:
BMC Geriatrics. 23
Background This research aimed to investigate the associations of anthropometric measurements, physiological parameters, chronic disease comorbidities, and social and lifestyle factors with cognitive function amongst community-dwelling older adults i
Autor:
Peiyu Wang, Renwu Zhou, Rusen Zhou, Wenshao Li, Janith Weerasinghe, Shuxiong Chen, Bernd H. A. Rehm, Liqian Zhao, Francesca D. Frentiu, Zhifa Zhang, Kexin Yan, Mary Lor, Andreas Suhrbier, Derek J. Richard, Erik W. Thompson, Kostya Ken Ostrikov, Xiaofeng Dai
Publikováno v:
Theranostics. 12:2811-2832