Potentiation of neuromuscular transmission by a small molecule calcium channel gating modifier improves motor function in a severe spinal muscular atrophy mouse model

Autor: Kristine S Ojala, Cassandra J Kaufhold, Mykenzie R Davey, Donggyun Yang, Mary Liang, Peter Wipf, Yomna Badawi, Stephen D Meriney

Publikováno v: Human Molecular Genetics. 32:1901-1911

Spinal muscular atrophy (SMA) is a monogenic disease that clinically manifests as severe muscle weakness owing to neurotransmission defects and motoneuron degeneration. Individuals affected by SMA experience neuromuscular weakness that impacts functi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a8d4f5e4be897d59a49af15be06bee41
https://doi.org/10.1093/hmg/ddad019

The Daniel K. Inouye Solar Telescope: status update and first results

Autor: Thomas R. Rimmele, Mark Warner, Roberto Casini, Jeffery Kuhn, Haosheng Lin, Friedrich Woeger, Alexandra Tritschler, Alisdair Davey, Alfred de Wijn, Andre Fehlmann, David Harrington, Sarah Jaeggli, Thomas Schad, Tetsu Anan, Christian Beck, Heather Marshall, Paul Jeffers, Andrew Beard, Chris Berst, Eric Cross, Bryan K. Cummings, Colleen Donneley, Arthur Eigenbrot, Andrew Ferayorni, Christopher Foster, Chriselle Galapon, Bret Goodrich, Brian S. Gregory, Stephanie Guzman, Stephen Guzzo, John Hubbard, Erik Johansson, Luke Johnson, Mary Liang, Brialyn Onodera, Myles Puentes, Lukas Rimmele, Erik Starman, Stacey Sueoka, Richard Summers, Aimee Szabo, Louis Szabo, Timothy Williams, Charles White

Publikováno v: Ground-based and Airborne Telescopes IX.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f43360190c5fb4c3f7603766997d4a4d
https://doi.org/10.1117/12.2644469

The Daniel K. Inouye Solar Telescope – Observatory Overview

Autor: Robert P. Hubbard, Aimee Szabo, Christopher Richards, Le Ellen Phelps, Heather K. Marshall, Kerry Gonzales, John R. Hubbard, Michael Knölker, Karl Newman, Mark Rast, Predrag Sekulic, Mary Liang, Colleen Donnelly, Christopher Gedrites, Brett Smith, Richard T. Summers, Christopher Foster, David Elmore, Sarah A. Jaeggli, Luke C. Johnson, Stephen B. Wampler, Brialyn Onodera, Thomas R. Rimmele, Isaac McQuillen, Joseph P. McMullin, Jeff Kuhn, Robert Rosner, David M. Harrington, Jean Benoit de Vanssay, Alisdair Davey, Stephen Guzzo, Bruce A. Cowan, Andrew Ferayorni, Stephanie S. Guzman, Steve Hegwer, Stacey R. Sueoka, Lukas M. Rimmele, Wolfgang Schmidt, Alfred G. de Wijn, Charles White, Friedrich Wöger, Erik M. Johansson, Jacobus M. Oschmann, Stephan R. Shimko, Tetsu Anan, Bryan K. Cummings, Oskar von der Lühe, Chriselle Ann Galapon, David C. Berst, Chen Liang, Mihalis Mathioudakis, Andrew Beard, Timothy R. Williams, Bret D. Goodrich, Simon C. Craig, Brett E. Simison, Myles M. Puentes, Stephen L. Keil, Haosheng Lin, Eric Cross, Thomas A. Schad, Erik Starman, Brian S. Gregory, Philip R. Goode, Christopher Mayer, Christian Beck, Donald L. Mickey, Roberto Casini, Arthur D. Eigenbrot, André Fehlmann, Louis Szabo, Alexandra Tritschler, Paul F. Jeffers, Mark Warner

Publikováno v: Rimmele, T R, Warner, M, Keil, S L, Goode, P R, Knölker, M, Kuhn, J R, Rosner, R R, McMullin, J P, Casini, R, Lin, H, Wöger, F, von der Lühe, O, Tritschler, A, Davey, A, de Wijn, A, Elmore, D F, Fehlmann, A, Harrington, D M, Jaeggli, S A, Rast, M P, Schad, T A, Schmidt, W, Mathioudakis, M, Mickey, D L, Anan, T, Beck, C, Marshall, H K, Jeffers, P F, Oschmann, J M, Beard, A, Berst, D C, Cowan, B A, Craig, S C, Cross, E, Cummings, B K, Donnelly, C, de Vanssay, J B, Eigenbrot, A D, Ferayorni, A, Foster, C, Galapon, C A, Gedrites, C, Gonzales, K, Goodrich, B D, Gregory, B S, Guzman, S S, Guzzo, S, Hegwer, S, Hubbard, R P, Hubbard, J R, Johansson, E M, Johnson, L C, Liang, C, Liang, M, McQuillen, I, Mayer, C, Newman, K, Onodera, B, Phelps, L E, Puentes, M M, Richards, C, Rimmele, L M, Sekulic, P, Shimko, S R, Simison, B E, Smith, B, Starman, E, Sueoka, S R, Summers, R T, Szabo, A, Szabo, L, Wampler, S B, Williams, T R & White, C 2020, ' The Daniel K. Inouye Solar Telescope – Observatory Overview ', Solar Physics, vol. 295, no. 12, 172 . https://doi.org/10.1007/s11207-020-01736-7

We present an overview of the National Science Foundation’sDaniel K. Inouye Solar Telescope(DKIST), its instruments, and support facilities. The 4 m aperture DKIST provides the highest-resolution observations of the Sun ever achieved. The large ape

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cae3d2aedb8dce89f37a06cde40c7715
https://pure.qub.ac.uk/en/publications/the-daniel-k-inouye-solar-telescope--observatory-overview(53af38b9-36ac-4c48-b702-0f5da5a26390).html

Separated Right and Left Systemic Venous Drainage

Autor: Choon Seng Adrian Shoen Low, Wei Ming Chua, Moon-Sun Mary Liang, Han Zhang

Publikováno v: Radiol Cardiothorac Imaging

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::141a8a0d6ed0b8e9fbf3854fdedcdfb4
https://doi.org/10.1148/ryct.2020200015

Effectiveness of Analogs of the GS-Nitroxide, JP4-039, as Total Body Irradiation Mitigators

Autor: Joel S. Greenberger, Michael W. Epperly, Joshua R. Sacher, Tanja Krainz, Xiaolin Zhang, Renee Fisher, Peter Wipf, Mary Liang, Hong Wang, Song Li

Background/aim Mitochondrial-targeted gramicidin S (GS)-nitroxide, JP4-039, has been demonstrated to be a potent radiation mitigator, and safe over a wide dose range. In addition, JP4-039 has organ-specific effectiveness when locally applied. Materia

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5dbdea035292a3b75ade9c39fb45770
https://europepmc.org/articles/PMC5267945/