Zobrazeno 1 - 10 of 10 pro vyhledávání: '"Mary L. Stackpole"'
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Akademický článek
Cost-effective methylome sequencing of cell-free DNA for accurately detecting and locating cancer
Autor: Mary L. Stackpole, Weihua Zeng, Shuo Li, Chun-Chi Liu, Yonggang Zhou, Shanshan He, Angela Yeh, Ziye Wang, Fengzhu Sun, Qingjiao Li, Zuyang Yuan, Asli Yildirim, Pin-Jung Chen, Paul Winograd, Benjamin Tran, Yi-Te Lee, Paul Shize Li, Zorawar Noor, Megumi Yokomizo, Preeti Ahuja, Yazhen Zhu, Hsian-Rong Tseng, James S. Tomlinson, Edward Garon, Samuel French, Clara E. Magyar, Sarah Dry, Clara Lajonchere, Daniel Geschwind, Gina Choi, Sammy Saab, Frank Alber, Wing Hung Wong, Steven M. Dubinett, Denise R. Aberle, Vatche Agopian, Steven-Huy B. Han, Xiaohui Ni, Wenyuan Li, Xianghong Jasmine Zhou
Publikováno v: Nature Communications, Vol 13, Iss 1, Pp 1-12 (2022)
Abstract Early cancer detection by cell-free DNA faces multiple challenges: low fraction of tumor cell-free DNA, molecular heterogeneity of cancer, and sample sizes that are not sufficient to reflect diverse patient populations. Here, we develop a ca
Externí odkaz: https://doaj.org/article/20fb32eadefd4ac09f8fb1699d2139b7
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3
Akademický článek
Sensitive detection of tumor mutations from blood and its application to immunotherapy prognosis
Autor: Shuo Li, Zorawar S. Noor, Weihua Zeng, Mary L. Stackpole, Xiaohui Ni, Yonggang Zhou, Zuyang Yuan, Wing Hung Wong, Vatche G. Agopian, Steven M. Dubinett, Frank Alber, Wenyuan Li, Edward B. Garon, Xianghong Jasmine Zhou
Publikováno v: Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
It is possible to call single-nucleotide variant (SNV) in cell-free DNA (cfDNA), but the accuracy of detection is often affected by low tumour cfDNA content. Here, the authors develop a method, cfSNV, and show that it can be used even for medium-cove
Externí odkaz: https://doaj.org/article/b75641b56a1844ef8994d8abd02e0b66
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7
cfTrack: A Method of Exome-Wide Mutation Analysis of Cell-free DNA to Simultaneously Monitor the Full Spectrum of Cancer Treatment Outcomes Including MRD, Recurrence, and Evolution
Autor: Shuo Li, Weihua Zeng, Xiaohui Ni, Yonggang Zhou, Mary L. Stackpole, Zorawar S. Noor, Zuyang Yuan, Adam Neal, Sanaz Memarzadeh, Edward B. Garon, Steven M. Dubinett, Wenyuan Li, Xianghong Jasmine Zhou
Publikováno v: Clin Cancer Res
Purpose:Cell-free DNA (cfDNA) offers a noninvasive approach to monitor cancer. Here we develop a method using whole-exome sequencing (WES) of cfDNA for simultaneously monitoring the full spectrum of cancer treatment outcomes, including minimal residu
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45a0a86e4f8bfffe85d2320c2bb99679
https://doi.org/10.1158/1078-0432.ccr-21-1242
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Abstract 567: cMonitor: Comprehensive and sensitive monitoring of diverse cancer treatment outcomes by exome-wide mutation analysis in plasma cfDNA
Autor: Xianghong Zhou, Zorawar S. Noor, Wenyuan Li, Edward B. Garon, Yonggang Zhou, Zuyang Yuan, Shuo Li, Xiaohui Ni, Mary L. Stackpole, Weihua Zeng, Steven M. Dubinett
Publikováno v: Cancer Research. 81:567-567
Monitoring cancer patients for the early detection of minimal residual disease (MRD), cancer recurrence, and cancer progression is essential for assessing treatment response and predicting early relapse during/after treatment. Plasma cell-free DNA (c
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1e962b81789a6fa0203d3b305953a0f8
https://doi.org/10.1158/1538-7445.am2021-567
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