Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Mary L. Kaldunski"'
Autor:
Mary L Kaldunski, Jennifer R Smith, Kent C Brodie, Jeffrey L De Pons, Wendy M Demos, Adam C Gibson, G Thomas Hayman, Logan Lamers, Stanley J F Laulederkind, Ketaki Thorat, Jyothi Thota, Marek A Tutaj, Monika Tutaj, Mahima Vedi, Shur-Jen Wang, Stacy Zacher, Melinda R Dwinell, Anne E Kwitek
Publikováno v:
GENETICS.
Rare diseases individually affect relatively few people, but as a group they impact considerable numbers of people. The Rat Genome Database (https://rgd.mcw.edu) is a knowledgebase that offers resources for rare disease research. This includes diseas
Autor:
Mahima Vedi, Jennifer R Smith, G Thomas Hayman, Monika Tutaj, Kent C Brodie, Jeffrey L De Pons, Wendy M Demos, Adam C Gibson, Mary L Kaldunski, Logan Lamers, Stanley J F Laulederkind, Jyothi Thota, Ketaki Thorat, Marek A Tutaj, Shur-Jen Wang, Stacy Zacher, Melinda R Dwinell, Anne E Kwitek
Publikováno v:
GENETICS. 224
The Rat Genome Database (RGD, https://rgd.mcw.edu) has evolved from simply a resource for rat genetic markers, maps, and genes, by adding multiple genomic data types and extensive disease and phenotype annotations and developing tools to effectively
Autor:
Angela M Henschel, Susanne M Cabrera, Mary L Kaldunski, Shuang Jia, Rhonda Geoffrey, Mark F Roethle, Vy Lam, Yi-Guang Chen, Xujing Wang, Nita H Salzman, Martin J Hessner
Publikováno v:
PLoS ONE, Vol 13, Iss 1, p e0190351 (2018)
Environmental changes associated with modern lifestyles may underlie the rising incidence of Type 1 diabetes (T1D). Our previous studies of T1D families and the BioBreeding (BB) rat model have identified a peripheral inflammatory state that is associ
Externí odkaz:
https://doaj.org/article/8069ac9084344b759a849304ae2c4684
Autor:
Mahima Vedi, Harika S Nalabolu, Chien-Wei Lin, Matthew J Hoffman, Jennifer R Smith, Kent Brodie, Jeffrey L De Pons, Wendy M Demos, Adam C Gibson, G Thomas Hayman, Morgan L Hill, Mary L Kaldunski, Logan Lamers, Stanley J F Laulederkind, Ketaki Thorat, Jyothi Thota, Monika Tutaj, Marek A Tutaj, Shur-Jen Wang, Stacy Zacher, Melinda R Dwinell, Anne E Kwitek
Publikováno v:
Genetics. 220
Biological interpretation of a large amount of gene or protein data is complex. Ontology analysis tools are imperative in finding functional similarities through overrepresentation or enrichment of terms associated with the input gene or protein list
Autor:
J L De Pons, Anne E. Kwitek, G. T. Hayman, Jennifer R. Smith, M L Hill, Jyothi Thota, Stan Laulederkind, A C Gibson, H S Nalabolu, Matthew Hoffman, Shur Jen Wang, S Zacher, Melinda R. Dwinell, W M Demos, Mary L. Kaldunski, L Lamers, Marek Tutaj, Monika Tutaj, K Thorat, K Brodie, Mahima Vedi
Publikováno v:
Mammalian Genome
Model organism research is essential for discovering the mechanisms of human diseases by defining biologically meaningful gene to disease relationships. The Rat Genome Database (RGD, (https://rgd.mcw.edu)) is a cross-species knowledgebase and the pre
Autor:
Bryon D. Johnson, Martin J. Hessner, Alexander C. Mackinnon, Pippa Simpson, Shuang Jia, Katie Palen, Laura McOlash, Mary L. Kaldunski, Jian Zhang, Jenny Grewal, Michael B. Dwinell, Susan Tsai, Mohammed Aldakkak, Jill A. Gershan
Publikováno v:
Cancer Epidemiology, Biomarkers & Prevention. 28:680-689
Background: Despite the accessibility of blood, identification of systemic biomarkers associated with cancer progression has been especially challenging. The aim of this study was to determine a difference in baseline serum immune signatures in patie
Autor:
Shuang Jia, Mary L. Kaldunski, Yi-Guang Chen, Carla J. Greenbaum, Martin J. Hessner, Rhonda Geoffrey, Pippa Simpson, Susanne M. Cabrera, Aniko Szabo, Samuel Engle, Cate Speake
Publikováno v:
Diabetologia
Aims/hypothesis The study aimed to determine whether discrete subtypes of type 1 diabetes exist, based on immunoregulatory profiles at clinical onset, as this has significant implications for disease treatment and prevention as well as the design and
Autor:
G. Thomas Hayman, Matthew Hoffman, Jeff De Pons, Jyothi Thota, Melinda R. Dwinell, Santoshi L R Ellanki, Mary L. Kaldunski, Marek Tutaj, Monika Tutaj, Harika S Nalabolu, Shur-Jen Wang, Jennifer R. Smith, Stanley J. F. Laulederkind, Mary Shimoyama, Anne E. Kwitek
Publikováno v:
Nucleic Acids Research
Formed in late 1999, the Rat Genome Database (RGD, https://rgd.mcw.edu) will be 20 in 2020, the Year of the Rat. Because the laboratory rat, Rattus norvegicus, has been used as a model for complex human diseases such as cardiovascular disease, diabet
Autor:
Melissa Reske, James W. Verbsky, Susanna A. McColley, Shuang Jia, Melodee Nugent, Keven Johnson, Michael W. Quasney, Mary K. Dahmer, Pippa Simpson, Trivikram Dasu, Katherine Woods, Xi Zhang, Martin J. Hessner, Diana Quintero, Justin E. Ideozu, Carolyn L. Cannon, Amy Pan, Michael M. Renda, Ellis D. Avner, Mary L. Kaldunski, Howard J. Jacob, Philip M. Farrell, Hara Levy, Rachel A. Feliciano, Kathy Murkowski
Although cystic fibrosis (CF) is attributed to dysfunction of a single gene, the relationships between the abnormal gene product and the development of inflammation and progression of lung disease are not fully understood, which limits our ability to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee24731e6d7e58fd71daaf0f276eb445
https://europepmc.org/articles/PMC6383551/
https://europepmc.org/articles/PMC6383551/
Autor:
Susanne M. Cabrera, Mary L. Kaldunski, Mark F. Roethle, Martin J. Hessner, Rhonda Geoffrey, Xujing Wang, Shuang Jia, Vy Lam, Angela M. Henschel, Yi-Guang Chen, Nita H. Salzman
Publikováno v:
PLoS ONE
PLoS ONE, Vol 13, Iss 1, p e0190351 (2018)
PLoS ONE, Vol 13, Iss 1, p e0190351 (2018)
Environmental changes associated with modern lifestyles may underlie the rising incidence of Type 1 diabetes (T1D). Our previous studies of T1D families and the BioBreeding (BB) rat model have identified a peripheral inflammatory state that is associ