Zobrazeno 1 - 10
of 123
pro vyhledávání: '"Mary Kay Lobo"'
Publikováno v:
Frontiers in Neural Circuits, Vol 17 (2023)
Externí odkaz:
https://doaj.org/article/ed30bc8102794503b3c40e5996693205
Autor:
Shannon L. Cole, Ramesh Chandra, Maya Harris, Ishan Patel, Torrance Wang, Hyunjae Kim, Leah Jensen, Scott J. Russo, Gustavo Turecki, Amy M. Gancarz-Kausch, David M. Dietz, Mary Kay Lobo
Publikováno v:
Molecular Brain, Vol 14, Iss 1, Pp 1-14 (2021)
Abstract Mitochondrial function is required for brain energy homeostasis and neuroadaptation. Recent studies demonstrate that cocaine affects mitochondrial dynamics and morphological characteristics within the nucleus accumbens (NAc). Further, mitoch
Externí odkaz:
https://doaj.org/article/9d6dd2987a8d4db7bdc5e26bc0388cab
Autor:
Marco Pagliusi, Daniela Franco, Shannon Cole, Gessynger Morais-Silva, Ramesh Chandra, Megan E. Fox, Sergio D. Iñiguez, Cesar R. Sartori, Mary Kay Lobo
Publikováno v:
Frontiers in Psychiatry, Vol 13 (2022)
Brain-derived neurotrophic factor (BDNF) has a critical role in stress response including neuropsychiatric disorders that are precipitated by stress, such as major depressive disorder (MDD). BDNF acts through its full-length BDNF receptor tyrosine ki
Externí odkaz:
https://doaj.org/article/63a364e767b7450cb66e9182269b8803
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 16 (2022)
Chronic stress can increase the risk of developing a substance use disorder in vulnerable individuals. Numerous models have been developed to probe the underlying neurobiological mechanisms, however, most prior work has been restricted to male rodent
Externí odkaz:
https://doaj.org/article/1eca3f08e14148cbbc689537af2b0111
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-7 (2020)
Abstract Stress alters the structure and function of brain reward circuitry and is an important risk factor for developing depression. In the nucleus accumbens (NAc), structural and physiological plasticity of medium spiny neurons (MSNs) have been li
Externí odkaz:
https://doaj.org/article/d16bc7fad6024b85a3b46d766c46053b
Autor:
Cali A. Calarco, Megan E. Fox, Saskia Van Terheyden, Makeda D. Turner, Jason B. Alipio, Ramesh Chandra, Mary Kay Lobo
Publikováno v:
Frontiers in Psychiatry, Vol 12 (2021)
The potency of the synthetic opioid fentanyl and its increased clinical availability has led to the rapid escalation of use in the general population, increased recreational exposure, and subsequently opioid-related overdoses. The wide-spread use of
Externí odkaz:
https://doaj.org/article/6a32ccad24e64c72be590cb3f98c0f71
Autor:
Jennifer A. Martin, Craig T. Werner, Swarup Mitra, Ping Zhong, Zi-Jun Wang, Pedro H. Gobira, Andrew. F. Stewart, Jay Zhang, Kyra Erias, Justin N. Siemian, Devin Hagarty, Lauren E. Mueller, Rachael L. Neve, Jun-Xu Li, Ramesh Chandra, Karen C. Dietz, Mary Kay Lobo, Amy M. Gancarz, Zhen Yan, David M. Dietz
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
The underlying transcriptional and cellular events mediating the reduction of dendritic spines on medium spiny neurons of the nucleus accumbens (NAc) remains unknown. Here, authors demonstrate that heroin self-administration negatively regulates the
Externí odkaz:
https://doaj.org/article/fd3986183cd145e696e221b400cee251
Autor:
Su Xu PhD, Wenjun Zhu MS, Yamin Wan MD, PhD, JiaBei Wang PhD, Xi Chen PhD, Liya Pi PhD, Mary Kay Lobo PhD, Bin Ren PhD, Zhekang Ying PhD, Michael Morris MD, Qi Cao MD, PhD
Publikováno v:
Molecular Imaging, Vol 17 (2018)
Minimal hepatic encephalopathy (MHE) is highly prevalent, observed in up to 80% of patients with liver dysfunction. Minimal hepatic encephalopathy is defined as hepatic encephalopathy with cognitive deficits and no grossly evident neurologic abnormal
Externí odkaz:
https://doaj.org/article/824fee8cbdfe4fc197041bb0addb43bb
Autor:
Ramesh Chandra, Mary Kay Lobo
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 11 (2017)
Immediate early genes (IEGs) were traditionally used as markers of neuronal activity in striatum in response to stimuli including drugs of abuse such as psychostimulants. Early studies using these neuronal activity markers led to important insights i
Externí odkaz:
https://doaj.org/article/250d47de928e4844bbdb8d456bbd3a74