Zobrazeno 1 - 10
of 105
pro vyhledávání: '"Mary Kay Floeter"'
Publikováno v:
Frontiers in Neurology, Vol 11 (2020)
A repeat expansion mutation in the C9orf72 gene causes amyotrophic lateral sclerosis (ALS), frontotemporal dementia (FTD), or symptoms of both, and has been associated with gray and white matter changes in brain MRI scans. We used graph theory to exa
Externí odkaz:
https://doaj.org/article/c2cf3d207a0b43e58f306cc101ce6af0
Publikováno v:
NeuroImage: Clinical, Vol 28, Iss , Pp 102354- (2020)
Previous cross-sectional imaging studies found differences in brain structure and in resting state networks between presymptomatic carriers of mutations in C9orf72 (C9+) and healthy controls. We carried out a prospective longitudinal study of clinica
Externí odkaz:
https://doaj.org/article/6f53455938bb43599fdd125ff673c55b
Autor:
Agustin M. Cardenas, Joelle E. Sarlls, Justin Y. Kwan, Devin Bageac, Zachary S. Gala, Laura E. Danielian, Abhik Ray-Chaudhury, Hao-Wei Wang, Karla L. Miller, Sean Foxley, Saad Jbabdi, Robert C. Welsh, Mary Kay Floeter
Publikováno v:
NeuroImage: Clinical, Vol 15, Iss , Pp 200-208 (2017)
Objectives: The goal of this study was to better understand the changes in tissue microstructure that underlie white matter diffusion changes in ALS patients. Methods: Diffusion tensor imaging was carried out in postmortem brains of 4 ALS patients an
Externí odkaz:
https://doaj.org/article/3bfe259fdd7240018697a78ea462a4a2
Autor:
Mary Kay Floeter, Tania F. Gendron
Publikováno v:
Frontiers in Neurology, Vol 9 (2018)
Now that genetic testing can identify persons at risk for developing amyotrophic lateral sclerosis (ALS) many decades before symptoms begin, there is a critical need for biomarkers that signal the onset and progression of degeneration. The search for
Externí odkaz:
https://doaj.org/article/c2bd76ef5c4e43b5918cf73bd924355c
Autor:
Mary Kay Floeter, Devin Bageac, Laura E. Danielian, Laura E. Braun, Bryan J. Traynor, Justin Y. Kwan
Publikováno v:
NeuroImage: Clinical, Vol 12, Iss C, Pp 1035-1043 (2016)
Expansion mutations in the C9orf72 gene may cause amyotrophic lateral sclerosis (ALS), frontotemporal dementia (FTD), or mixtures of the two clinical phenotypes. Different imaging findings have been described for C9orf72-associated diseases in compar
Externí odkaz:
https://doaj.org/article/f88d19c05b074be7991ae3920933395d
Publikováno v:
BMC Neurology, Vol 17, Iss 1, Pp 1-3 (2017)
Abstract Background Seronegative ocular myasthenia gravis (OMG) is diagnosed by ocular symptoms with supporting SFEMG, typically of frontalis or extensor digitorum muscles. We aimed to determine the sensitivity and specificity of orbicularis oculi SF
Externí odkaz:
https://doaj.org/article/d806c31e248747aa8b88bfae5551a18c
Autor:
Avner Meoded, Arthur E. Morrissette, Rohan Katipally, Olivia Schanz, Stephen J. Gotts, Mary Kay Floeter
Publikováno v:
NeuroImage: Clinical, Vol 7, Iss C, Pp 288-296 (2015)
Increased functional connectivity in resting state networks was found in several studies of patients with motor neuron disorders, although diffusion tensor imaging studies consistently show loss of white matter integrity. To understand the relationsh
Externí odkaz:
https://doaj.org/article/1c7ee482f3a34acfaf8cf04a23172793
Autor:
Avner Meoded, Justin Y. Kwan, Tracy L. Peters, Edward D. Huey, Laura E. Danielian, Edythe Wiggs, Arthur Morrissette, Tianxia Wu, James W. Russell, Elham Bayat, Jordan Grafman, Mary Kay Floeter
Publikováno v:
Dementia and Geriatric Cognitive Disorders Extra, Vol 3, Iss 1, Pp 233-250 (2013)
Introduction: Executive dysfunction occurs in many patients with amyotrophic lateral sclerosis (ALS), but it has not been well studied in primary lateral sclerosis (PLS). The aims of this study were to (1) compare cognitive function in PLS to that in
Externí odkaz:
https://doaj.org/article/00d400cc4e004750b765ead818d38df3
Autor:
Justin Y Kwan, Suh Young Jeong, Peter Van Gelderen, Han-Xiang Deng, Martha M Quezado, Laura E Danielian, John A Butman, Lingye Chen, Elham Bayat, James Russell, Teepu Siddique, Jeff H Duyn, Tracey A Rouault, Mary Kay Floeter
Publikováno v:
PLoS ONE, Vol 7, Iss 4, p e35241 (2012)
Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disorder characterized by cortical and spinal motor neuron dysfunction. Routine magnetic resonance imaging (MRI) studies have previously shown hypointense signal in the motor cort
Externí odkaz:
https://doaj.org/article/0f7888cfdc984453a07d2db754a8f3a8
Autor:
Sabrina Paganoni, Hiroshi Mitsumoto, James Wymer, Mary Kay Floeter, Deborah L. Warden, Dale J. Lange
Publikováno v:
Amyotroph Lateral Scler Frontotemporal Degener
Primary lateral sclerosis (PLS) is an extremely rare central nervous system degenerative disorder characterized by slowly progressive upper motor neuron loss leading to severe limb and bulbar dysfunction and disability. Although not necessarily life-