Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Mary Kate Hart"'
Autor:
Paul W Fenimore, Majidat A Muhammad, William M Fischer, Brian T Foley, Russell R Bakken, James R Thurmond, Karina Yusim, Hyejin Yoon, Michael Parker, Mary Kate Hart, John M Dye, Bette Korber, Carla Kuiken
Publikováno v:
PLoS ONE, Vol 7, Iss 10, p e44769 (2012)
We report the rational design and in vivo testing of mosaic proteins for a polyvalent pan-filoviral vaccine using a computational strategy designed for the Human Immunodeficiency Virus type 1 (HIV-1) but also appropriate for Hepatitis C virus (HCV) a
Externí odkaz:
https://doaj.org/article/dad067caf3604da993bc5c6b4a7606b3
Publikováno v:
Emerging Infectious Diseases, Vol 8, Iss 1, Pp 94-96 (2002)
Mycoplasma contamination of the licensed anthrax vaccine administered to military personnel has been suggested as a possible cause of Persian Gulf illness. Vaccine samples tested by nonmilitary laboratories were negative for viable mycoplasma and myc
Externí odkaz:
https://doaj.org/article/758f017b82fe461f842210f072e23ade
Autor:
Hank Lockman, P.F. Fellows, Roy E. Barnewall, Mary Kate Hart, Shannon S. Martin, Karen Metcalfe, Robert Krile, Jessica Price
Publikováno v:
Clinical and Vaccine Immunology. 22:1070-1078
The efficacy of a recombinant plague vaccine (rF1V) was evaluated in cynomolgus macaques (CMs) to establish the relationship among vaccine doses, antibody titers, and survival following an aerosol challenge with a lethal dose of Yersinia pestis strai
Autor:
Mary Kate Hart, Wael El-Amin, Sandor Fritsch, Maikel V. W. van der Velden, Barbara Grohmann-Izay, Gerald Aichinger, P. Noel Barrett, Otfried Kistner, Manuela Koska, Daniel Portsmouth
Publikováno v:
Clinical and Vaccine Immunology. 22:46-55
Studies on candidate pandemic vaccines against avian influenza viruses have focused on H5N1, but viruses of other subtypes, such as A/H9N2, are also considered to have pandemic potential. We investigated the safety and immunogenicity of two immunizat
Autor:
John M. Dye, Samantha E. Zak, James F. Barth, Andrew S. Herbert, Majidat A. Muhammad, Kurt Kamrud, Ana I. Kuehne, Mary Kate Hart, Ramon A. Ortiz, Gene G. Olinger, Jennifer L. Groebner, Donald K. Nichols, William D. Pratt, Jonathan F. Smith, John S. Lee, Spencer W. Stonier, Max Custer, Russell R. Bakken, Laura I. Prugar
Publikováno v:
Journal of Virology. 87:4952-4964
There are no vaccines or therapeutics currently approved for the prevention or treatment of ebolavirus infection. Previously, a replicon vaccine based on Venezuelan equine encephalitis virus (VEEV) demonstrated protective efficacy against Marburg vir
Autor:
Teri Ann S. Wong, Russell R. Bakken, Mary Kate Hart, Axel T. Lehrer, William D. Pratt, David E. Clements, Michael M. Lieberman, John M. Dye, Tom Humphreys
Publikováno v:
Vaccine
Infections with filoviruses in humans are highly virulent, causing hemorrhagic fevers which result in up to 90% mortality. In addition to natural infections, the ability to use these viruses as bioterrorist weapons is of significant concern. Currentl
Autor:
Gregory Berezuk, Hartmut J. Ehrlich, Julia Singer, Sandor Fritsch, Wael El-Amin, P. Noel Barrett, Otfried Kistner, Gerald Aichinger, Mary Kate Hart, Daniel Portsmouth
Publikováno v:
Vaccine. 30:4377-4386
Background Cell culture technologies have the potential to improve the robustness and flexibility of influenza vaccine supply and to substantially shorten manufacturing timelines. We investigated the safety, immunogenicity and efficacy of a Vero cell
Autor:
Daniel Portsmouth, Julia Singer, Otfried Kistner, Gerald Aichinger, P. Noel Barrett, Mary Kate Hart, Wael El-Amin, Sandor Fritsch, Gregory Berezuk, Hartmut J. Ehrlich
Publikováno v:
Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
A Vero cell culture–derived seasonal influenza vaccine provides consistently high levels of protection against cell culture–confirmed infection over a complete influenza season. Influenza symptoms are also less severe and of shorter duration in i
Autor:
Michael D. Parker, Marilyn J. Buckley, Mary Kate Hart, Pamela J. Glass, Vanessa R. Melanson, David Norwood
Publikováno v:
Journal of Virology. 84:12683-12690
Six monoclonal antibodies were isolated that exhibited specificity for a furin cleavage site deletion mutant (V3526) of Venezuelan equine encephalitis virus (VEEV). These antibodies comprise a single competition group and bound the E3 glycoprotein of
Autor:
Ed Barr, William Mega, Mary Kate Hart, William C. Blackwelder, P.F. Fellows, Robert Sherwood, Winston Lin, Trevor Brasel, Amanda M. Rom, Lou Holland, Justin Hartings, Jeffrey J. Adamovicz, Jessica Price, Stephen R. Morris, Doris Snow
Publikováno v:
Vaccine. 28:7748-7756
Passive transfer models were developed to evaluate the ability of antibodies generated in cynomolgus macaques and humans vaccinated with a recombinant plague vaccine (rF1V) to protect naïve Swiss Webster mice against pneumonic plague. Development of