Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Mary Kate, Tracey"'
Autor:
Neil C. Dalvie, Joseph R. Brady, Laura E. Crowell, Mary Kate Tracey, Andrew M. Biedermann, Kawaljit Kaur, John M. Hickey, D. Lee Kristensen, Alexandra D. Bonnyman, Sergio A. Rodriguez-Aponte, Charles A. Whittaker, Marina Bok, Celina Vega, Tarit K. Mukhopadhyay, Sangeeta B. Joshi, David B. Volkin, Viviana Parreño, Kerry R. Love, J. Christopher Love
Publikováno v:
Microbial Cell Factories, Vol 20, Iss 1, Pp 1-14 (2021)
Abstract Background Vaccines comprising recombinant subunit proteins are well-suited to low-cost and high-volume production for global use. The design of manufacturing processes to produce subunit vaccines depends, however, on the inherent biophysica
Externí odkaz:
https://doaj.org/article/41653df3a0e545ec8a33dc49cc46216b
Autor:
J. Christopher Love, John M. Hickey, David D. Weis, Kerry R. Love, Joseph R. Brady, Sanjeev Agarwal, Nishant Sawant, David B. Volkin, Mary Kate Tracey, Kawaljit Kaur, Jian Xiong, David A. Holland, Sangeeta B. Joshi, Neil C. Dalvie, Tarit Mukhopadhyay
Publikováno v:
Journal of Pharmaceutical Sciences
In a companion paper, a two-step developability assessment is presented to rapidly evaluate low-cost formulations (multi-dose, aluminum-adjuvanted) for new subunit vaccine candidates. As a case study, a non-replicating rotavirus (NRRV) recombinant pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0e2ff4fa158cb685c1de46cd1f1d053
https://doi.org/10.1016/j.xphs.2020.11.033
https://doi.org/10.1016/j.xphs.2020.11.033
Autor:
J. Christopher Love, Laura E. Crowell, Umesh Shaligram, Neil C. Dalvie, Rakesh R Lothe, Christopher A Naranjo, Seraphin Castelino, Ryan S Johnston, Charles A. Whittaker, Meghraj P Rajurkar, Harish D Rao, Mary Kate Tracey, Andrew M. Biedermann, Sergio A. Rodriguez-Aponte
Publikováno v:
bioRxiv
article-version (status) pre
article-version (number) 1
article-version (status) pre
article-version (number) 1
Prevention of COVID-19 on a global scale will require the continued development of high-volume, low-cost platforms for the manufacturing of vaccines to supply ongoing demand. Vaccine candidates based on recombinant protein subunits remain important b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::613b82185e05456fbd6b807c8e291c47
https://pubmed.ncbi.nlm.nih.gov/33880471
https://pubmed.ncbi.nlm.nih.gov/33880471
Autor:
Charles A. Whittaker, Aiquan Chang, J. Christopher Love, Hanne Leth Andersen, Lisa H. Tostanoski, Ozan S. Kumru, Nicolas Collin, Brooke Fiala, Megan Lok, Neil P. King, Brittany L. Hartwell, Danielle L Camp, Joseph R. Brady, Mary Kate Tracey, Andrew M. Biedermann, Kristen A Rodrigues, Harry Kleanthous, Jing Yang Wang, Katherine McMahan, Judith M. Silverman, Murillo Silva, Sergio A. Rodriguez-Aponte, David B. Volkin, Darrell J. Irvine, Thomas Courant, Maciel Porto, Sangeeta B. Joshi, Jingyou Yu, Patrice M. Dubois, Swagata Kar, Dan H. Barouch, Ashley A. Lemnios, Lauren Carter, Christopher A Naranjo, Ryan S Johnston, Celia Lebas, Dongsoo Yun, Neil C. Dalvie, Carl Walkey, Natalie Brunette, Laura E. Crowell, Kerry R. Love, Kawaljit Kaur, Mark G. Lewis
Publikováno v:
bioRxiv
article-version (status) pre
article-version (number) 1
article-version (status) pre
article-version (number) 1
Global containment of COVID-19 still requires accessible and affordable vaccines for low- and middle-income countries (LMICs).1 Recently approved vaccines provide needed interventions, albeit at prices that may limit their global access.2 Subunit vac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8f708622e17cebfff295c987cf72435
https://doi.org/10.1073/pnas.2106845118
https://doi.org/10.1073/pnas.2106845118
Autor:
Neil C, Dalvie, Andrew M, Biedermann, Sergio A, Rodriguez-Aponte, Christopher A, Naranjo, Harish D, Rao, Meghraj P, Rajurkar, Rakesh R, Lothe, Umesh S, Shaligram, Ryan S, Johnston, Laura E, Crowell, Seraphin, Castelino, Mary Kate, Tracey, Charles A, Whittaker, J Christopher, Love
Publikováno v:
Biotechnology and Bioengineering
Prevention of COVID‐19 on a global scale will require the continued development of high‐volume, low‐cost platforms for the manufacturing of vaccines to supply ongoing demand. Vaccine candidates based on recombinant protein subunits remain impor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e13ddee7f526f0dd15890f8f18331d0c
https://pubmed.ncbi.nlm.nih.gov/34780057
https://pubmed.ncbi.nlm.nih.gov/34780057
Autor:
Kristen A Rodrigues, Mary Kate Tracey, Andrew M. Biedermann, Harry Kleanthous, Darrell J. Irvine, Judith M. Silverman, Danielle L Camp, Kerry R. Love, Lauren Carter, Thomas Courant, Neil C. Dalvie, Lisa H. Tostanoski, Megan Lok, J. Christopher Love, Nicolas Collin, Katherine McMahan, Swagata Kar, Hanne Leth Andersen, Ashley A. Lemnios, Charles A. Whittaker, Laura E. Crowell, Celia Lebas, Ozan S. Kumru, Joseph R. Brady, Brittany L. Hartwell, Sergio A. Rodriguez-Aponte, Kawaljit Kaur, David B. Volkin, Murillo Silva, Maciel Porto, Patrice M. Dubois, Dan H. Barouch, Neil P. King, Mark G. Lewis, Aiquan Chang, Sangeeta B. Joshi, Jingyou Yu, Christopher A Naranjo, Ryan S Johnston, Dongsoo Yun
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance Most of the global population resides in low- and middle-income countries, where current vaccines for COVID-19 remain largely unavailable. For the COVID-19 pandemic, the world will need access to >10 billion doses of vaccines, or more th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6373cc0f780250cecb0fb11b4efe5894
https://pubmed.ncbi.nlm.nih.gov/34493582
https://pubmed.ncbi.nlm.nih.gov/34493582
Autor:
J. Christopher Love, Chaz Goodwine, Neil C. Dalvie, Kerry R. Love, Sergio A. Rodriguez, Mariana Puntel, Steven M. Cramer, Viviana Parreño, Lucia Rocha, Andrés Wigdorovitz, Carla Sosa Holt, Laura E. Crowell, Mary Kate Tracey, Celina G. Vega
Publikováno v:
Wiley
Biotechnology and Bioengineering
Biotechnology and Bioengineering
Single‐domain antibodies (sdAbs) offer the affinity and therapeutic value of conventional antibodies, with increased stability and solubility. Unlike conventional antibodies, however, sdAbs do not benefit from a platform manufacturing process. Whil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a19bb206b6d4f767346acc2fd54fd50
https://hdl.handle.net/1721.1/135524
https://hdl.handle.net/1721.1/135524
Autor:
Neil Dalvie, Joseph Brady, Laura Crowell, Mary Kate Tracey, Andrew Biedermann, Kawalijt Kaur, John M. Hickey, Duane Lee Kristensen, Alexandra Bonnyman, Sergio Rodriguez-Aponte, Charles Whittaker, Marina Bok, Celina Vega, Tarit Mukhopadhyay, Sangeeta Joshi, David Volkin, Viviana Parreno, Kerry R. Love, J. Christopher Love
BackgroundVaccines comprising recombinant subunit proteins are well-suited to low-cost and high-volume production for global use. The design of manufacturing processes to produce subunit vaccines depends, however, on the inherent biophysical traits p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b7e68d62bf639141984e50bb4f32d7f1
https://doi.org/10.21203/rs.3.rs-113853/v1
https://doi.org/10.21203/rs.3.rs-113853/v1