Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Mary K. Young"'
Autor:
Rebecca M. Carpenter, Mary K. Young, William A. O. Petri, Genevieve R. Lyons, Carol Gilchrist, Robert M. Carey, William A. Petri
Publikováno v:
mSphere, Vol 7, Iss 4 (2022)
ABSTRACT The coronavirus SARS-CoV-2 infects host cells by binding to the angiotensin-converting enzyme 2 (ACE2) receptor, which belongs to an anti-inflammatory, anti-thrombotic counter-regulatory arm of the renin-angiotensin system (RAS). ACE2 dysfun
Externí odkaz:
https://doaj.org/article/309e79d509e94e528d8d57f4197e48ab
Autor:
Alexandra N. Donlan, Tara E. Sutherland, Chelsea Marie, Saskia Preissner, Benjamin T. Bradley, Rebecca M. Carpenter, Jeffrey M. Sturek, Jennie Z. Ma, G. Brett Moreau, Jeffrey R. Donowitz, Gregory A. Buck, Myrna G. Serrano, Stacey L. Burgess, Mayuresh M. Abhyankar, Cameron Mura, Philip E. Bourne, Robert Preissner, Mary K. Young, Genevieve R. Lyons, Johanna J. Loomba, Sarah J. Ratcliffe, Melinda D. Poulter, Amy J. Mathers, Anthony J. Day, Barbara J. Mann, Judith E. Allen, William A. Petri Jr.
Publikováno v:
JCI Insight, Vol 6, Iss 15 (2021)
Immune dysregulation is characteristic of the more severe stages of SARS-CoV-2 infection. Understanding the mechanisms by which the immune system contributes to COVID-19 severity may open new avenues to treatment. Here, we report that elevated IL-13
Externí odkaz:
https://doaj.org/article/a6c6e0e467c54cfc87c0eba3f4b21036
Autor:
Mayuresh M. Abhyankar, Mark T. Orr, Robert Kinsey, Sandra Sivananthan, Andrew J. Nafziger, David N. Oakland, Mary K. Young, Laura Farr, Md Jashim Uddin, Jhansi L. Leslie, Stacey L. Burgess, Hong Liang, Ines De Lima, Elise Larson, Jeffrey A. Guderian, Susan Lin, Aaron Kahn, Prakash Ghosh, Sierra Reed, Mark A. Tomai, Karl Pedersen, William A. Petri, Christopher B. Fox
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Amebiasis is a neglected tropical disease caused by Entamoeba histolytica. Although the disease burden varies geographically, amebiasis is estimated to account for some 55,000 deaths and millions of infections globally per year. Children and traveler
Externí odkaz:
https://doaj.org/article/27f8546d80654205a8c42df32dd87af3
Autor:
Jennifer M. Sasson, Joseph J. Campo, Rebecca M. Carpenter, Mary K. Young, Arlo Z. Randall, Krista Trappl-Kimmons, Amit Oberai, Christopher Hung, Joshua Edgar, Andy A. Teng, Jozelyn V. Pablo, Xiaowu Liang, Angela Yee, William A. Petri, David Camerini
Publikováno v:
mBio, Vol 12, Iss 3 (2021)
As numerous viral variants continue to emerge in the coronavirus disease 2019 (COVID-19) pandemic, determining antibody reactivity to SARS-CoV-2 epitopes becomes essential in discerning changes in the immune response to infection over time. This stud
Externí odkaz:
https://doaj.org/article/5ec3f7b6d8bd4efc99be2f0428769176
IL-33 drives group 2 innate lymphoid cell-mediated protection during Clostridium difficile infection
Autor:
Alyse L. Frisbee, Mahmoud M. Saleh, Mary K. Young, Jhansi L. Leslie, Morgan E. Simpson, Mayuresh M. Abhyankar, Carrie A. Cowardin, Jennie Z. Ma, Patcharin Pramoonjago, Stephen D. Turner, Alice P. Liou, Erica L. Buonomo, William A. Petri
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
Here, Frisbee et al. show that hypervirulent Clostridium difficile induces IL-33 expression in the gut and IL-33 reduces mortality and morbidity via group 2 innate lymphoid cells. Furthermore, serum levels of the soluble IL-33 decoy receptor, sST2, a
Externí odkaz:
https://doaj.org/article/8ea0571b5e634edeb6f07d5f54e6abfd
Autor:
Gregory R. Madden, Isaura Rigo, Rachel Boone, Mayuresh M. Abhyankar, Mary K. Young, William Basener, William A. Petri
Publikováno v:
Infection and Immunity. 91
Traditional clinical models for predicting recurrent Clostridioides difficile infection do not perform well, likely owing to the complex host-pathogen interactions involved. Accurate risk stratification using novel biomarkers could help prevent recur
Autor:
Mary K Young, Jhansi L Leslie, Gregory R Madden, David M Lyerly, Robert J Carman, Matthew W Lyerly, David B Stewart, Mayuresh M Abhyankar, William A Petri
Publikováno v:
Open Forum Infectious Diseases. 9
Background The incidence of Clostridioides difficile infection (CDI) has increased over the past 2 decades and is considered an urgent threat by the Centers for Disease Control and Prevention. Hypervirulent strains such as ribotype 027, which possess
Autor:
David M. Lyerly, William A. Petri, Jhansi L. Leslie, Mayuresh M. Abhyankar, David B Stewart, Gregory R Madden, Robert J. Carman, Mary K Young
BackgroundThe incidence of Clostridioides difficile infection (CDI) has increased over the past two decades and is considered an urgent threat by the Centers for Disease Control. Hypervirulent strains such as ribotype 027, that possess genes for an a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d2346accde5540480b311f21e9815ddb
https://doi.org/10.1101/2021.07.30.21261256
https://doi.org/10.1101/2021.07.30.21261256
Autor:
Mary K, Young, Jhansi L, Leslie, Gregory R, Madden, David M, Lyerly, Robert J, Carman, Matthew W, Lyerly, David B, Stewart, Mayuresh M, Abhyankar, William A, Petri
Publikováno v:
Open forum infectious diseases. 9(3)
The incidence ofWe retrospectively tested stool from 215 CDI patients for CDT by enzyme-linked immunosorbent assay (ELISA). Stratifying patients by CDT status, we assessed if disease severity and clinical outcomes correlated with CDT positivity. Addi
Autor:
Christopher Hung, Joseph J. Campo, Xiaowu Liang, William A. Petri, Mary K. Young, Angela Yee, Arlo Randall, Andy Teng, David Camerini, Rebecca M Carpenter, Amit Oberai, Krista Trappl-Kimmons, Joshua Edgar, Jennifer M. Sasson, Jozelyn Pablo
Publikováno v:
mBio, Vol 12, Iss 3 (2021)
mBio
mBio
We sought to discover links between antibody responses to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and patient clinical variables, cytokine profiles, and antibodies to endemic coronaviruses. Serum samples from 30 patients of young
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9832d26c59c19cccad976d119d0ccd8
https://doi.org/10.1101/2021.01.12.21249702
https://doi.org/10.1101/2021.01.12.21249702