Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Mary K. Treutelaar"'
Intrinsic cardiorespiratory fitness modulates clinical and molecular response to caloric restriction
Autor:
Johanna Y. Fleischman, Nathan R. Qi, Mary K. Treutelaar, Steven L. Britton, Lauren G. Koch, Jun Z. Li, Charles F. Burant
Publikováno v:
Molecular Metabolism, Vol 68, Iss , Pp 101668- (2023)
Objective: Caloric restriction (CR) is one extrinsic intervention that can improve metabolic health, and it shares many phenotypical parallels with intrinsic high cardiorespiratory fitness (CRF), including reduced adiposity, increased cardiometabolic
Externí odkaz:
https://doaj.org/article/6ad0ecfb704e47dfb502e9fa9b84a894
Autor:
Yu-Yu Ren, Katherine A Overmyer, Nathan R Qi, Mary K Treutelaar, Lori Heckenkamp, Molly Kalahar, Lauren G Koch, Steven L Britton, Charles F Burant, Jun Z Li
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e77588 (2013)
Aerobic capacity is a strong predictor of all-cause mortality and can influence many complex traits. To explore the biological basis underlying this connection, we developed via artificial selection two rat lines that diverge for intrinsic (i.e. inbo
Externí odkaz:
https://doaj.org/article/7b2375c877494977b4e0e82e43c45cef
Autor:
Leah C. Solberg Woods, Ayse Bilge Ozel, Mary K. Treutelaar, Shweta Ramdas, Myrna Mandell, Katie Holl, Jun Li
Publikováno v:
Scientific Data
Scientific Data, Vol 6, Iss 1, Pp 1-7 (2019)
Scientific Data, Vol 6, Iss 1, Pp 1-7 (2019)
We performed whole-genome sequencing for eight inbred rat strains commonly used in genetic mapping studies. They are the founders of the NIH heterogeneous stock (HS) outbred colony. We provide their sequences and variant calls to the rat genomics com
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6d74e103826313e50c691e79894763e
Autor:
Monica J. Hubal, Heidi B. IglayReger, Amy E. Rothberg, Charles F. Burant, Paul M. Gordon, Mary K. Treutelaar, Jacques Robidoux, Eric P. Hoffman, Flor E Morales, Evan P. Nadler, Jeffrey F. Horowitz, Dongmei Liu, Hisham A. Barakat
Local inflammation in obese adipose tissue has been shown to contribute to insulin resistance; however, the role of macrophage infiltration within skeletal muscle is still debatable. This study aimed to evaluate the association of skeletal muscle mac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a04ce6a6190974ebdbf6035852427cd3
https://europepmc.org/articles/PMC6284171/
https://europepmc.org/articles/PMC6284171/
Autor:
Charles F. Burant, Mahmoud El-Azzouny, Mary K. Treutelaar, Charles R. Evans, Robert T. Kennedy
Publikováno v:
Journal of Biological Chemistry. 289:13575-13588
Acute fatty acid (FA) exposure potentiates glucose-stimulated insulin secretion in β cells through metabolic and receptor-mediated effects. We assessed the effect of fatty acids on the dynamics of the metabolome in INS-1 cells following exposure to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::897b8734924aa9f1fda04e17959cd0a6
https://doi.org/10.1074/jbc.m113.531970
https://doi.org/10.1074/jbc.m113.531970
Autor:
S. L. Britton, Jun Li, Lauren G. Koch, Yu yu Ren, Mary K. Treutelaar, Charles F. Burant, Nathan Qi
We have previously established two lines of rat for studying the functional basis of aerobic exercise capacity (AEC) and its impact on metabolic health. The two lines, high capacity runners (HCR) and low capacity runners (LCR), have been selectively
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67fe893ca0b60933f50272059739115a
https://doi.org/10.1101/032441
https://doi.org/10.1101/032441
Autor:
Mary K. Treutelaar, Jun Li, Steven L. Britton, Yu yu Ren, Nathan Qi, Lauren G. Koch, Charles F. Burant
Intrinsic aerobic exercise capacity can influence many complex traits including obesity and aging. To study this connection we established two rat lines by divergent selection of untrained aerobic capacity. After 32 generations the high capacity runn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69472f349799ca8d808ea0efc9871943
https://doi.org/10.1101/013706
https://doi.org/10.1101/013706
Autor:
Kathleen Graziano, Mary K. Treutelaar, Lizhi Zhang, Diane M. Simeone, Craig D. Logsdon, Charles F. Burant, Lanjing Zhang
Publikováno v:
American Journal of Physiology-Endocrinology and Metabolism. 291:E1305-E1316
To investigate the role of transforming growth factor (TGF)-β family signaling in the adult pancreas, a transgenic mouse (E-dnSmad4) was created that expresses a dominant-negative Smad4 protein driven by a fragment of the elastase promoter. Although
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5a7bf6a8fd8775885e2dec732207d1f
https://doi.org/10.1152/ajpendo.00561.2005
https://doi.org/10.1152/ajpendo.00561.2005
Autor:
Mary K. Treutelaar, Claudia L. Dias-Leme, Lizhi Zhang, Donna M. Martin, Manami Hara, Diane M. Simeone, Charles F. Burant, Jennifer M. Skidmore
Publikováno v:
Diabetes. 52:2503-2512
To clarify the lineage relationship between cells that express the neural stem cell marker nestin and endocrine cells of the pancreas, we analyzed offspring of a cross between mice carrying a nestin promoter/enhancer-driven cre-recombinase (Nestin-cr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fa53a70bfb4dc9c8594ef4316b3479d
https://doi.org/10.2337/diabetes.52.10.2503
https://doi.org/10.2337/diabetes.52.10.2503
Autor:
Jun Li, Mary K. Treutelaar, Charles F. Burant, Molly Kalahar, Nathan Qi, Katherine A. Overmyer, Steven L. Britton, Lori Heckenkamp, Lauren G. Koch, Yu yu Ren
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e77588 (2013)
PLoS ONE
PLoS ONE
Aerobic capacity is a strong predictor of all-cause mortality and can influence many complex traits. To explore the biological basis underlying this connection, we developed via artificial selection two rat lines that diverge for intrinsic (i.e. inbo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7da948bcca194c309b35a9ff4dc353eb
http://europepmc.org/articles/PMC3795692?pdf=render
http://europepmc.org/articles/PMC3795692?pdf=render