Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Mary K. Luidens"'
Publikováno v:
AACE Clinical Case Reports, Vol 2, Iss 3, Pp e244-e246 (2016)
Objective: To present a serious complication of X-linked hereditary hypophosphatemia.Methods: The authors present the case of a 49-year-old man who presented to the hospital with back pain and was found to have a thoracic myelopathy caused by hypertr
Autor:
Faith B. Davis, Shaker A. Mousa, Mary K. Luidens, Sandra Incerpi, Heng Yuan Tang, Gennadi V. Glinsky, Aleck Hercbergs, Hung Yun Lin, Paul J. Davis
Publikováno v:
Endocrine Research. 38:112-118
BACKGROUND: Tetraiodothyroacetic acid (tetrac) and its nanoparticulate formulation (Nanotetrac) act at a cell surface receptor to block angiogenesis and tumor cell proliferation. OBJECTIVE: The complex anti-angiogenic properties of tetrac and Nanotet
Publikováno v:
Annual Review of Pharmacology and Toxicology. 51:99-115
Plasma membrane integrin αvβ3 is a cell surface receptor for thyroid hormone at which nongenomic actions are initiated. L-thyroxine (T4) and 3,3′,5-triiodo-L-thyronine (T3) promote angiogenesis and tumor cell proliferation via the receptor. Tetra
Publikováno v:
Vascular Pharmacology. 52:142-145
In models of thyroid hormone-induced cardiac hypertrophy, there is appropriate, supportive angiogenesis. Twenty years ago in one such model, angiogenesis in response to the hormone was observed before hypertrophy developed and it is now understood th
Publikováno v:
American Journal of Physiology-Endocrinology and Metabolism. 297:E1238-E1246
A thyroid hormone receptor on integrin αvβ3 that mediates cell surface-initiated nongenomic actions of thyroid hormone on tumor cell proliferation and on angiogenesis has been described. Transduction of the hormone signal into these recently recogn
Autor:
Faith B. Davis, Hung Yun Lin, Mary K. Luidens, H. James Cao, Travis Keating, Jennifer R. Grandis
Publikováno v:
Immunology‚ Endocrine & Metabolic Agents in Medicinal Chemistry. 9:203-218
Phorbol 12-myristate 13-acetate (PMA) affects a variety of cell processes, including proliferation and differentiation. In most normal cell types, PMA enhances proliferation by a protein kinase C (PKC)- dependent mechanism, while the proliferation of
Autor:
Mary K. Luidens, Mingzeng Sun, Aleck H. Hercbergs, Faith B. Davis, Gennadi V. Glinsky, Shaker A. Mousa, Heng Yuan Tang, Anna B. Glinskii, Hung Yun Lin, Paul J. Davis
Publikováno v:
Cell Cycle. 8:3562-3570
Tetraiodothyroacetic acid (tetrac) inhibits the cellular actions of thyroid hormone initiated at the hormone receptor on plasma membrane integrin alphavbeta3. Via interaction with the integrin, tetrac is also capable of inhibiting the angiogenic effe
Publikováno v:
Immunology‚ Endocrine & Metabolic Agents in Medicinal Chemistry. 9:84-89
Publikováno v:
Endocrine Research. 34:31-42
Introduction. In CV-1 cells, shuttling from cytoplasm to nucleus of the nuclear thyroid hormone receptor-β1 (TRβ1, TR) is shown in this report to be regulated by extracellular thyroid hormone at a hormone receptor on cell surface integrin αv3. Met
Autor:
Mary K. Luidens, Sandra Incerpi, John T. Leith, Heng Yuan Tang, Murat Yalcin, Shaker A. Mousa, Osnat Ashur-Fabian, Aleck Hercbergs, Thangirala Sudha, Hung Yun Lin, Paul J. Davis
Publikováno v:
OncoTargets and therapy
The extracellular domain of integrin αvβ3 contains a receptor for thyroid hormone and hormone analogs. The integrin is amply expressed by tumor cells and dividing blood vessel cells. The proangiogenic properties of thyroid hormone and the capacity