Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Mary K. Hondalus"'
Publikováno v:
mSphere, Vol 1, Iss 5 (2016)
ABSTRACT The soil-dwelling, saprophytic actinomycete Rhodococcus equi is a multihost, facultative intracellular pathogen of macrophages. When inhaled by susceptible foals, it causes severe bronchopneumonia. It is also a pathogen of pigs, which may de
Externí odkaz:
https://doaj.org/article/7bc4a47ec54342309074d72f23f65e10
Publikováno v:
Molecular Microbiology. 107:428-444
Rhodococcus equi is a multihost, facultative intracellular bacterial pathogen that primarily causes pneumonia in foals less than six months in age and immunocompromised people. Previous studies determined that the major virulence determinant of R. eq
Publikováno v:
PLoS ONE
PLoS ONE, Vol 13, Iss 10, p e0204475 (2018)
PLoS ONE, Vol 13, Iss 10, p e0204475 (2018)
Rhodococcus equi is a facultative intracellular bacterium of macrophages and is an important pathogen of animals and immunocompromised people wherein disease results in abcessation of the lungs and other sites. Prior work has shown that the presence
Publikováno v:
Antimicrobial Agents and Chemotherapy. 59:3633-3636
Treatment of mice with the combination of clarithromycin with rifampin resulted in a significantly lower number of Rhodococcus equi CFU in the organs of mice than treatment with either drug alone or placebo. There was no significant difference in the
Publikováno v:
Molecular microbiology. 107(3)
Rhodococcus equi is a multi-host, facultative intracellular bacterial pathogen that primarily causes pneumonia in foals less than six months in age and immunocompromised people. Previous studies determined that the major virulence determinant of R. e
Publikováno v:
Vaccine. 32:1362-1367
Background Equine neonates have reduced humoral and cell-mediated immune responses compared to adult horses after administration of killed vaccines. As a basis for this study, we hypothesized that newborn foals can mount strong immune responses after
Autor:
Stephen A. Hines, David W. Horohov, Noah D. Cohen, G. Muscatello, Monica Venner, Wim G. Meijer, Mary K. Hondalus, Steeve Giguère, S Cauchard, John F. Prescott, Julien Cauchard, A. Haas, José A. Vázquez-Boland
Publikováno v:
Equine Veterinary Journal. 45:523-526
Publikováno v:
Drug Delivery Systems for Tuberculosis Prevention and Treatment
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9fd351674e668a349961669964a44c84
https://doi.org/10.1002/9781118943182.ch5
https://doi.org/10.1002/9781118943182.ch5
Autor:
Londa J. Berghaus, Jose A. Vasquez-Boland, Mary K. Hondalus, Iain MacArthur, Elisa Anastasi, Noah D. Cohen, Steeve Giguère, Jennifer M. Willingham-Lane, Marilyn C. Roberts
Publikováno v:
The Journal of antimicrobial chemotherapy. 71(6)
Objectives The objective of this study was to identify the molecular mechanism of macrolide resistance in the actinomycete Rhodococcus equi, a major equine pathogen and zoonotic agent causing opportunistic infections in people. Methods Macrolide-resi
Autor:
Angela Carville, Mary K. Hondalus, Samantha L. Sampson, Barry R. Bloom, Elizabeth W. Howerth, Keith G. Mansfield, Teresa N. Quitugua, D. Mitchell Magee
Publikováno v:
Vaccine. 29:4839-4847
We have previously described the development of a live, fully attenuated Mycobacterium tuberculosis (Mtb) vaccine candidate strain with two independent attenuating auxotrophic mutations in leucine and pantothenate biosynthesis. In the present work, t