Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Mary K. Ernst"'
Publikováno v:
Molecular and Cellular Biology. 18:2640-2649
Members of the Rel/NF-kappaB family of transcription factors are related to each other over a region of about 300 amino acids called the Rel Homology Domain (RHD), which governs DNA binding, dimerization, and binding to inhibitor. At the C-terminal e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8db6f3cae8be1192c2e8dd480c7c6754
https://doi.org/10.1128/mcb.18.5.2640
https://doi.org/10.1128/mcb.18.5.2640
Autor:
Kouji Matsushima, Kouji Kuno, Mary K. Ernst, Nancy R. Rice, Naofumi Mukaida, Masafumi Ogata, Yuji Ishikawa
Publikováno v:
Journal of Biological Chemistry. 270:27914-27919
Nuclear factor kappa B (NF-kappa B) is stored in the cytoplasm as an inactive form through interaction with I kappa B. Stimulation of cells leads to a rapid phosphorylation of I kappa B alpha, which is presumed to be important for the subsequent degr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0bdf6cc1951c0b89116bd5b22c206933
https://doi.org/10.1074/jbc.270.46.27914
https://doi.org/10.1074/jbc.270.46.27914
Publikováno v:
Nature. 404(6780)
The tumour suppressor p53 inhibits cell growth through activation of cell-cycle arrest and apoptosis, and most cancers have either mutation within the p53 gene or defects in the ability to induce p53. Activation or re-introduction of p53 induces apop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0b37af006ef78b468588e988164aecc
https://pubmed.ncbi.nlm.nih.gov/10786798
https://pubmed.ncbi.nlm.nih.gov/10786798
Publikováno v:
Molecular cell. 4(5)
The E2F family of transcription factors plays an essential role in promoting cell cycle progression, and one member of the family, E2F-1, is also capable of inducing apoptosis. We show here that E2F-1 can induce apoptosis by a death receptor-dependen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb980d4014a152e1e606d171e89cba6c
https://pubmed.ncbi.nlm.nih.gov/10619024
https://pubmed.ncbi.nlm.nih.gov/10619024
Autor:
James L. Resnick, Sandy Becker, Dineli Wickramasinghe, Laura Grabel, John M. Centanni, Mary K. Ernst, Lino Tessarollo, Peter J. Donovan
Publikováno v:
Development (Cambridge, England). 121(7)
The cdc25 gene product is a tyrosine phosphatase that acts as an initiator of M-phase in eukaryotic cell cycles by activating p34cdc2. Here we describe the cloning and characterization of the developmental expression pattern of two mouse cdc25 homolo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a143fb1aa33e4582ca01f01208bf7c9
https://pubmed.ncbi.nlm.nih.gov/7635051
https://pubmed.ncbi.nlm.nih.gov/7635051
Publikováno v:
Molecular and cellular biology. 15(2)
In most cells, proteins belonging to the Rel/NF-kappa B family of transcription factors are held in inactive form in the cytoplasm by an inhibitor protein, I kappa B alpha. Stimulation of the cells leads to degradation of the inhibitor and transit of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c0bd25daba89286296cd449454e3318
https://pubmed.ncbi.nlm.nih.gov/7823953
https://pubmed.ncbi.nlm.nih.gov/7823953
Autor:
Nancy A. Jenkins, Peter J. Donovan, Dineli Wickramasinghe, Mary K. Ernst, N. G. Copeland, Debra J. Gilbert, Leslie F. Lock
Publikováno v:
Mammalian Genome. 7:771-772
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::580d7c45d5983cbb7911b982dd7875d2
https://doi.org/10.1007/s003359900230
https://doi.org/10.1007/s003359900230
Publikováno v:
Journal of Liquid Chromatography. 1:457-467
A method is presented for the determination of pmole levels of the carcinogenic metabolite N-hydroxy-2-acetylaminofluorene (N-hydroxy-AAF) formed from N-2-acetylaminofluorene (AAF) by cells in culture. The extract from the cells and cell incubation m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::119f0fd898f9ed8ebfc80149f29be56d
https://doi.org/10.1080/01483917808060011
https://doi.org/10.1080/01483917808060011
Publikováno v:
Journal of Applied Toxicology. 3:326-331
N-2-Acetylaminofluorene (AAF), a potent carcinogen in a variety of animal species and organs, was used to determine the metabolic capabilities of isolated organ cells in transformation as well as biochemical studies. Cells isolated from liver, lung,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9100d170bbf995274ccd02373cb4e723
https://doi.org/10.1002/jat.2550030611
https://doi.org/10.1002/jat.2550030611
Publikováno v:
Journal of Applied Toxicology. 3:196-202
The mechanism of benzo[a]pyrene (BP) by cultured kidney, liver, small intestine, lung and trachea from male Syrian golden hamsters and Sprague-Dawley rats was compared. The metabolic capacity of intact cell systems was assessed by determining the for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c43b33fc508d093a025b91ddc2fb859
https://doi.org/10.1002/jat.2550030407
https://doi.org/10.1002/jat.2550030407