Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Mary K. Dornon"'
Autor:
Bruno Boivin, Kasper C. D. Roet, Xuan Huang, Kyle W. Karhohs, Mohammad H. Rohban, Jack Sandoe, Ole Wiskow, Rie Maeda, Alyssa Grantham, Mary K. Dornon, Jenny Shao, Devlin Frost, Dylan Baker, Kevin Eggan, Anne E. Carpenter, Clifford J. Woolf
Publikováno v:
Molecular biology of the cell. 33(6)
Patient stem cell-derived models enable imaging of complex disease phenotypes and the development of scalable drug discovery platforms. Current preclinical methods for assessing cellular activity do not, however, capture the full intricacies of disea
Autor:
Rie Maeda, Anne E. Carpenter, Kyle W. Karhohs, Boivin B, Baker D, Alyssa Grantham, Mary K. Dornon, Mohammad Hossein Rohban, Ole Wiskow, Kevin Eggan, Kasper C. D. Roet, Devlin Frost, Shao J, Xin-Yun Huang, Jackson Sandoe, Clifford J. Woolf
Patient stem cell-derived models enable imaging of complex disease phenotypes and the development of scalable drug discovery platforms. Current preclinical methods for assessing cellular activity do not, however, capture the full intricacies of disea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9b17cadb7dd5f9567a3b7179ceacf874
https://doi.org/10.1101/2021.06.22.449195
https://doi.org/10.1101/2021.06.22.449195
Autor:
Ole Wiskow, Clifford J. Woolf, Kasper C. D. Roet, Jackie Klug-McLeod, Devlin Frost, Karen L. Leach, Kevin Eggan, Hongying Yang, Anthony J. Coyle, Allison P. Berg, Amy Brault, Anne B. Jefferson, Liying Zhang, Seungkyu Lee, Mary K. Dornon, Joseph R. Klim, Dongyi Zhao, Fabien Vincent, Rie Maeda, Kuchuan Chen, Xuan Huang, Alyssa Grantham
Publikováno v:
SSRN Electronic Journal.
Drug development is hampered by poor target selection. Phenotypic screens using cells differentiated from patient stem cells offer the possibility to validate known and discover novel disease targets in an unbiased fashion. To identify targets for ma
Autor:
Mary K. Dornon, Joseph R. Klim, Ole Wiskow, Allison P. Berg, Kevin Eggan, Clifford J. Woolf, Devlin Frost, Kuchuan Chen, Liying Zhang, Hongying Yang, Marco T. Siekmann, Karen L. Leach, Anthony J. Coyle, Seungkyu Lee, Jackie Klug-McLeod, Alyssa Grantham, Anne B. Jefferson, Dongyi Zhao, Xuan Huang, Lyn H. Jones, Fabien Vincent, Rie Maeda, Amy Brault, Kasper C.D. Roet
Publikováno v:
Cell reports
SUMMARY Drug development is hampered by poor target selection. Phenotypic screens using neurons differentiated from patient stem cells offer the possibility to validate known and discover novel disease targets in an unbiased fashion. To identify targ
Autor:
Roodolph St. Pierre, Lee Barrett, Clifford J. Woolf, Tom W. Muir, Hai T. Dao, Alfredo M. Valencia, Olubusayo Bolonduro, Zoe C. Yeoh, Clayton K. Collings, Crystal Hermawan, Cigall Kadoch, Yung-Chih Cheng, Zhen-Yu Sun, Mary K. Dornon, Nicholas E. Vangos, Dawn E. Comstock, Hyuk-Soo Seo, Sirano Dhe-Paganon, Nazar Mashtalir, Junwei Huang
Publikováno v:
Cell
Summary Mammalian switch/sucrose non-fermentable (mSWI/SNF) complexes are multi-component machines that remodel chromatin architecture. Dissection of the subunit- and domain-specific contributions to complex activities is needed to advance mechanisti