Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Mary K Schroth"'
Publikováno v:
Neurology and Therapy, Vol 13, Iss 3, Pp 583-598 (2024)
Abstract Background Spinal muscular atrophy (SMA) is an autosomal recessive neuromuscular disease characterized by progressive muscle weakness and atrophy. Clinical trial data suggest early diagnosis and treatment are critical. The purpose of this st
Externí odkaz:
https://doaj.org/article/e77e62e7f8324a64a293f7d6d9bcb8ef
Autor:
John T Kissel, Charles B Scott, Sandra P Reyna, Thomas O Crawford, Louise R Simard, Kristin J Krosschell, Gyula Acsadi, Bakri Elsheik, Mary K Schroth, Guy D'Anjou, Bernard LaSalle, Thomas W Prior, Susan Sorenson, Jo Anne Maczulski, Mark B Bromberg, Gary M Chan, Kathryn J Swoboda, Project Cure Spinal Muscular Atrophy Investigators' Network
Publikováno v:
PLoS ONE, Vol 6, Iss 7, p e21296 (2011)
BACKGROUNDMultiple lines of evidence have suggested that valproic acid (VPA) might benefit patients with spinal muscular atrophy (SMA). The SMA CARNIVAL TRIAL was a two part prospective trial to evaluate oral VPA and L-carnitine in SMA children. Part
Externí odkaz:
https://doaj.org/article/141aa541d70f4d909428010ea6f22fd6
Autor:
Kathryn J Swoboda, Charles B Scott, Thomas O Crawford, Louise R Simard, Sandra P Reyna, Kristin J Krosschell, Gyula Acsadi, Bakri Elsheik, Mary K Schroth, Guy D'Anjou, Bernard LaSalle, Thomas W Prior, Susan L Sorenson, Jo Anne Maczulski, Mark B Bromberg, Gary M Chan, John T Kissel, Project Cure Spinal Muscular Atrophy Investigators Network
Publikováno v:
PLoS ONE, Vol 5, Iss 8, p e12140 (2010)
Valproic acid (VPA) has demonstrated potential as a therapeutic candidate for spinal muscular atrophy (SMA) in vitro and in vivo.Two cohorts of subjects were enrolled in the SMA CARNIVAL TRIAL, a non-ambulatory group of "sitters" (cohort 1) and an am
Externí odkaz:
https://doaj.org/article/2a5f3943a1fe48acb839ca7db24528ca
Autor:
Kathryn J Swoboda, Charles B Scott, Sandra P Reyna, Thomas W Prior, Bernard LaSalle, Susan L Sorenson, Janine Wood, Gyula Acsadi, Thomas O Crawford, John T Kissel, Kristin J Krosschell, Guy D'Anjou, Mark B Bromberg, Mary K Schroth, Gary M Chan, Bakri Elsheikh, Louise R Simard
Publikováno v:
PLoS ONE, Vol 4, Iss 5, p e5268 (2009)
UNLABELLED:Preliminary in vitro and in vivo studies with valproic acid (VPA) in cell lines and patients with spinal muscular atrophy (SMA) demonstrate increased expression of SMN, supporting the possibility of therapeutic benefit. We performed an ope
Externí odkaz:
https://doaj.org/article/cf5b116376a74737bee79e5d14d205d2
Autor:
Rewais B. Hanna, Nick Nahm, Melissa A. Bent, Sarah Sund, Karen Patterson, Mary K. Schroth, Matthew A. Halanski
Publikováno v:
JBJS open access. 7(3)
The purpose of the present study was to define the prevalence of hip pain in nonambulatory children with spinal muscular atrophy (SMA) (type I or II) treated with aggressive medical management, prior to widespread use of disease-modifying therapies (
Autor:
Rosangel Cruz, Susan A. Hall, Angela D. Paradis, Jill Jarecki, Mary K. Schroth, Colleen McCarthy O’Toole, Nicole B. Johnson, Shannon O’Brien, Sandra P. Reyna, Lisa Belter, Cynthia C. Jones
Publikováno v:
Journal of Neuromuscular Diseases
Background: Cure SMA maintains the largest patient-reported database for people affected with spinal muscular atrophy (SMA). In 2017, Cure SMA initiated annual surveys with their membership to collect demographic and disease characteristics, healthca
Autor:
Matthew A. Halanski, Mary K. Schroth, Scott Hetzel, Meredith Schultz, Mark Sharafinski, Karen Patterson, Rewais Hanna, Sarah Sund, Kenneth J. Noonan
Publikováno v:
Spine Deformity. 8:547-552
Single center, retrospective chart review. To determine if routine posterior spinal fusion (PSF) is unnecessary in non-ambulatory growing rod graduates with SMA. Most non-ambulatory children with SMA develop early-onset scoliosis (EOS). Posterior gro
Autor:
Karen Patterson, Matthew A. Halanski, Meredith Schultz, Mary K. Schroth, Sarah Sund, Rewais Hanna, Meaghann S. Weaver, Scott Hetzel, Alice Yuroff
Publikováno v:
Journal of Child Neurology. 35:322-330
Background: Spinal muscular atrophy is an autosomal-recessive, progressive neuromuscular disease associated with extensive morbidity. Children with spinal muscular atrophy have potentially increased life spans due to improved nutrition, respiratory s
Publikováno v:
BMC Pediatrics
BMC Pediatrics, Vol 21, Iss 1, Pp 1-13 (2021)
BMC Pediatrics, Vol 21, Iss 1, Pp 1-13 (2021)
Background Spinal Muscular Atrophy (SMA), a leading genetic cause of death in infants, is an autosomal recessive neuromuscular disease characterized by progressive muscle weakness and atrophy. While early diagnosis of SMA is critical to modifying dis
Publikováno v:
Adhesion Molecules in Allergic Disease
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::069ea659e668c536f19ac2ad96439394
https://doi.org/10.1201/9781003067603-11
https://doi.org/10.1201/9781003067603-11