Elevated plasma angiopoietin-2 levels and primary graft dysfunction after lung transplantation.

Autor: Joshua M Diamond, Mary K Porteous, Edward Cantu, Nuala J Meyer, Rupal J Shah, David J Lederer, Steven M Kawut, James Lee, Scarlett L Bellamy, Scott M Palmer, Vibha N Lama, Sangeeta M Bhorade, Maria Crespo, Ejigayehu Demissie, Keith Wille, Jonathan Orens, Pali D Shah, Ann Weinacker, David Weill, Selim Arcasoy, David S Wilkes, Lorraine B Ware, Jason D Christie, Lung Transplant Outcomes Group

Publikováno v: PLoS ONE, Vol 7, Iss 12, p e51932 (2012)

INTRODUCTION:Primary graft dysfunction (PGD) is a significant contributor to early morbidity and mortality after lung transplantation. Increased vascular permeability in the allograft has been identified as a possible mechanism leading to PGD. Angiop

Externí odkaz: https://doaj.org/article/25861605064c473f9a7ffb6dd6428564

Idiopathic pulmonary fibrosis is associated with common genetic variants and limited rare variants

Autor: Anna L. Peljto, Rachel Z. Blumhagen, Avram D. Walts, Jonathan Cardwell, Julia Powers, Tamera J. Corte, Joanne L. Dickinson, Ian Glaspole, Yuben P. Moodley, Martina Koziar Vasakova, Elisabeth Bendstrup, Jesper R. Davidsen, Raphael Borie, Bruno Crestani, Philippe Dieude, Francesco Bonella, Ulrich Costabel, Gunnar Gudmundsson, Seamas C. Donnelly, Jim Egan, Michael T. Henry, Michael P. Keane, Marcus P. Kennedy, Cormac McCarthy, Aoife N. McElroy, Joshua A. Olaniyi, Katherine M. A. O’Reilly, Luca Richeldi, Paolo M. Leone, Venerino Poletti, Francesco Puppo, Sara Tomassetti, Valentina Luzzi, Nurdan Kokturk, Nesrin Mogulkoc, Christine A. Fiddler, Nikhil Hirani, R. Gisli Jenkins, Toby M. Maher, Philip L. Molyneaux, Helen Parfrey, Rebecca Braybrooke, Timothy S. Blackwell, Peter D. Jackson, Steven D. Nathan, Mary K. Porteous, Kevin K. Brown, Jason D. Christie, Harold R. Collard, Oliver Eickelberg, Elena E. Foster, Kevin F. Gibson, Marilyn Glassberg, Daniel J. Kass, Jonathan A. Kropski, David Lederer, Angela L. Linderholm, Jim Loyd, Susan K. Mathai, Sydney B. Montesi, Imre Noth, Justin M. Oldham, Amy J. Palmisciano, Cristina A. Reichner, Mauricio Rojas, Jesse Roman, Neil Schluger, Barry S. Shea, Jeffrey J. Swigris, Paul J. Wolters, Yingze Zhang, Cecilia M. A. Prele, Juan I. Enghelmayer, Maria Otaola, Christopher J. Ryerson, Mauricio Salinas, Martina Sterclova, Tewodros H. Gebremariam, Marjukka Myllärniemi, Roberto G. Carbone, Haruhiko Furusawa, Masaki Hirose, Yoshikazu Inoue, Yasunari Miyazaki, Ken Ohta, Shin Ohta, Tsukasa Okamoto, Dong Soon Kim, Annie Pardo, Moises Selman, Alvaro U. Aranda, Moo Suk Park, Jong Sun Park, Jin Woo Song, Maria Molina-Molina, Lurdes Planas-Cerezales, Gunilla Westergren-Thorsson, Albert V. Smith, Ani W. Manichaikul, John S. Kim, Stephen S. Rich, Elizabeth C. Oelsner, R. Graham Barr, Jerome I. Rotter, Josee Dupuis, George O’Connor, Ramachandran S. Vasan, Michael H. Cho, Edwin K. Silverman, Marvin I. Schwarz, Mark P. Steele, Joyce S. Lee, Ivana V. Yang, Tasha E. Fingerlin, David A. Schwartz

Rationale: Idiopathic pulmonary fibrosis is a rare, irreversible, and progressive disease of the lungs. Common genetic variants, in addition to non-genetic factors, have been consistently associated with IPF. Rare variants identified by candidate gen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0670c24aedc8efa23979477ed15d39b
http://hdl.handle.net/10044/1/101620

Risk of primary graft dysfunction following lung transplantation in selected adults with connective tissue disease-associated interstitial lung disease

Autor: Mary K. Porteous, David J. Lederer, Laurel Kalman, Elana J. Bernstein, Michelle Oyster, Jason D. Christie, Pali D. Shah, Jonathan P. Singer, Chadi A. Hage, Joshua M. Diamond, Jonathan B. Orens, Laurie D. Snyder, Edward Cantu, Keith M. Wille, Jake G. Natalini, Steven M. Kawut, Vibha N. Lama, John F. McDyer, Ann Weinacker, Lorraine B. Ware

Publikováno v: J Heart Lung Transplant

Background Previous studies have reported similarities in long-term outcomes following lung transplantation for connective tissue disease-associated interstitial lung disease (CTD-ILD) and idiopathic pulmonary fibrosis (IPF). However, it is unknown w

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ff457833418ea733885a3f0cba4b8d8
https://doi.org/10.1016/j.healun.2021.01.1391

Lung Innate Lymphoid Cell Composition Is Altered in Primary Graft Dysfunction

Autor: David Artis, Mary K. Porteous, Steven A. Saenz, Edward Cantu, Jason D. Christie, Joshua M. Diamond, Elia D. Tait Wojno, Laurel A. Monticelli

Publikováno v: American Journal of Respiratory and Critical Care Medicine. 201:63-72

Rationale: Primary graft dysfunction (PGD) is the leading cause of early morbidity and mortality after lung transplantation, but the immunologic mechanisms are poorly understood. Innate lymphoid cells (ILC) are a heterogeneous family of immune cells

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2689fb80c38efba582d29eef7a00c628
https://doi.org/10.1164/rccm.201906-1113oc

Hospitalizations in patients with idiopathic pulmonary fibrosis

Autor: Anna J. Podolanczuk, Joao A. Andrade, Nishant Gupta, Ather Siddiqi, Megan L. Neely, David J. Lederer, Nina Patel, Jesse Roman, Murali Ramaswamy, Rajat Walia, Yolanda Mageto, Shirin Shafazand, Amy Hajari Case, Joseph A. Lasky, Doug Lee, Kalpalatha K. Guntupalli, Mark P. Steele, Wael Asi, Hyun J Kim, Tracy Luckhardt, Timothy Liesching, Paul Sachs, Mary E. Strek, Sally Suliman, Kevin F. Gibson, Laurie D. Snyder, David Hotchkin, Randolph J. Lipchik, Kevin R. Flaherty, Eric S. White, Justin M. Oldham, Timothy P.M. Whelan, Mary K. Porteous, Imre Noth, Craig S Conoscenti, Prema Menon, Daniel F. Dilling, Jeremy Tabak, John Fitzgerald, Scott Beegle, Marilyn K. Glassberg, Lisa Lancaster, Francis Cordova, Rishi Raj, Tessy Paul, Paul Mohabir, Mridu Gulati, Ayodeji Adegunsoye, Andrew Namen, Tristan J. Huie, Robert J. Kaner, Lake Morrison, Leann Silhan, Rany Condos, David Zhang, Zeenat Safdar, John A. Belperio, Maryl Kreider, Albert Baker, Daniel A. Culver, Tonya D. Russell, Howard J. Huang, Shaun Bender, Barry Sigal, Jason Lobo

Publikováno v: Respiratory Research
Respiratory Research, Vol 22, Iss 1, Pp 1-9 (2021)

Background Hospitalizations are common among patients with idiopathic pulmonary fibrosis (IPF). We investigated the impact of hospitalizations on outcomes in patients with IPF. Methods The IPF-PRO Registry is an observational US registry that enrolle

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b0b4332b7090e7a7b6090e4a80d5a67
http://europepmc.org/articles/PMC8481759