Zobrazeno 1 - 10
of 67
pro vyhledávání: '"Mary Jo, Wick"'
Autor:
Charles Caër, Mary Jo Wick
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Inflammatory bowel disease (IBD), including Crohn's disease and ulcerative colitis, is a complex immune-mediated disease of the gastrointestinal tract that increases morbidity and negatively influences the quality of life. Intestinal mononuclear phag
Externí odkaz:
https://doaj.org/article/a9f646bba870436487a2c7760870dd34
Publikováno v:
Blood Advances, Vol 1, Iss 13, Pp 835-838 (2017)
Externí odkaz:
https://doaj.org/article/b8a86979573945509016658f8c52e595
Autor:
Frida Gorreja, Charles Caër, Stephen T. A. Rush, Sophia K. Forsskål, Anetta Härtlova, Maria K. Magnusson, Elinor Bexe Lindskog, Lars G. Börjesson, Mattias Block, Mary Jo Wick
Publikováno v:
Inflammation. 45:1631-1650
Inflammasomes are intracellular protein complexes whose activation results in proinflammatory cytokines. Inflammasomes are implicated in Crohn´s disease (CD) pathogenesis, yet the contribution of inflammasomes in intestinal epithelial cells (IECs) v
Autor:
Siggeir F. Brynjolfsson, Linn Persson Berg, Teresa Olsen Ekerhult, Inga Rimkute, Mary-Jo Wick, Inga-Lill Mårtensson, Ola Grimsholm
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Even though more than 30 years have passed since the eradication of smallpox, high titers of smallpox-specific antibodies are still detected in the blood of subjects vaccinated in childhood. In fact, smallpox-specific antibody levels are maintained i
Externí odkaz:
https://doaj.org/article/41afc33e3e734e86847f7906cf576e9e
Autor:
Louis Szeponik, Lars Börjesson, Frida Gorreja, Charles Caër, Siggeir F Brynjolfsson, Maria K. Magnusson, Sophia K Forsskåhl, Mary Jo Wick, Elinor Bexe-Lindskog, Mattias Block
Publikováno v:
Journal of Crohn's & Colitis
Background and Aims Uncontrolled activation of intestinal mononuclear phagocytes [MNPs] drives chronic inflammation in inflammatory bowel disease [IBD]. Triggering receptor expressed on myeloid cells 1 [TREM-1] has been implicated in the pathogenesis
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0130750 (2015)
Mucus alterations are a feature of ulcerative colitis (UC) and can drive inflammation by compromising the mucosal barrier to luminal bacteria. The exact pathogenesis of UC remains unclear, but CD4+ T cells reacting to commensal antigens appear to con
Externí odkaz:
https://doaj.org/article/5d9160d1bea644f0aac7e6d02055f11d
Autor:
Ulf A Wenzel, Maria K Magnusson, Anna Rydström, Caroline Jonstrand, Julia Hengst, Malin E V Johansson, Anna Velcich, Lena Öhman, Hans Strid, Henrik Sjövall, Gunnar C Hansson, Mary Jo Wick
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e100217 (2014)
The colonic mucus layer plays a critical role in intestinal homeostasis by limiting contact between luminal bacteria and the mucosal immune system. A defective mucus barrier in animal models allows bacterial contact with the intestinal epithelium and
Externí odkaz:
https://doaj.org/article/30219f5197424d7ba699777a13b458d9
Autor:
Mary Jo Wick, Johannes Alfredsson
Publikováno v:
Scandinavian Journal of Immunology
Crohn's disease (CD) is a chronic inflammatory disease of the gastrointestinal tract that leads to substantial suffering for millions of patients. In some patients, the chronic inflammation leads to remodelling of the extracellular matrix and fibrosi
Autor:
Mary Jo Wick, Charles Caër
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Frontiers in Immunology
Frontiers in Immunology
Inflammatory bowel disease (IBD), including Crohn's disease and ulcerative colitis, is a complex immune-mediated disease of the gastrointestinal tract that increases morbidity and negatively influences the quality of life. Intestinal mononuclear phag
Autor:
William W. Agace, Mary Jo Wick, María Fernández-Santoscoy, Emma Persson, Ulf Alexander Wenzel, Ulf Yrlid
Publikováno v:
Immunology Letters. 176:72-80
CD103(+)CD11b(+) dendritic cells (DC) are the major migratory DC subset in the small intestine lamina propria (siLP) and their survival is dependent on the transcription factor interferon regulatory factor 4 (IRF4). Mice with a DC-specific deletion o