Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Mary Jane, Navarro"'
Autor:
Marcos C. Miranda, Elizabeth Kepl, Mary Jane Navarro, Chengbo Chen, Max Johnson, Kaitlin R. Sprouse, Cameron Stewart, Anne Palser, Adian Valdez, Deleah Pettie, Claire Sydeman, Cassandra Ogohara, John C. Kraft, Minh Pham, Michael Murphy, Sam Wrenn, Brooke Fiala, Rashmi Ravichandran, Daniel Ellis, Lauren Carter, Davide Corti, Paul Kellam, Kelly Lee, Alexandra C. Walls, David Veesler, Neil P. King
Publikováno v:
npj Vaccines, Vol 9, Iss 1, Pp 1-14 (2024)
Abstract We previously described a two-component protein nanoparticle vaccine platform that displays 60 copies of the SARS-CoV-2 spike protein RBD (RBD-NP). The vaccine, when adjuvanted with AS03, was shown to elicit robust neutralizing antibody and
Externí odkaz:
https://doaj.org/article/649dcf2c588340c39547078121604655
Autor:
Daniel Ellis, Natalie Brunette, Katharine H. D. Crawford, Alexandra C. Walls, Minh N. Pham, Chengbo Chen, Karla-Luise Herpoldt, Brooke Fiala, Michael Murphy, Deleah Pettie, John C. Kraft, Keara D. Malone, Mary Jane Navarro, Cassandra Ogohara, Elizabeth Kepl, Rashmi Ravichandran, Claire Sydeman, Maggie Ahlrichs, Max Johnson, Alyssa Blackstone, Lauren Carter, Tyler N. Starr, Allison J. Greaney, Kelly K. Lee, David Veesler, Jesse D. Bloom, Neil P. King
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
The unprecedented global demand for SARS-CoV-2 vaccines has demonstrated the need for highly effective vaccine candidates that are thermostable and amenable to large-scale manufacturing. Nanoparticle immunogens presenting the receptor-binding domain
Externí odkaz:
https://doaj.org/article/ee4c16cc940d4a98bc65cf319a369f9a
Autor:
Leslie S. Itsara, Yaxian Zhou, Julie Do, Samrita Dungel, Matthew E. Fishbaugher, Will W. Betz, Thao Nguyen, Mary Jane Navarro, Erika L. Flannery, Ashley M. Vaughan, Stefan H. I. Kappe, Anil K. Ghosh
Publikováno v:
Malaria Journal, Vol 17, Iss 1, Pp 1-13 (2018)
Abstract Background Despite the importance of the Plasmodium berghei oocyst capsule protein (PbCap380) in parasite survival, very little is known about the orthologous Plasmodium falciparum capsule protein (PfCap380). The goal of this work was to stu
Externí odkaz:
https://doaj.org/article/6f4b2269acd6441080313f82bdc857a3
Autor:
M. Alejandra Tortorici, Alessandra Franzetti Pellanda, Amalio Telenti, Alexandra C. Walls, Christian Garzoni, Jessica Bassi, Herbert W. Virgin, Mary-Jane Navarro, David Veesler, Christian Saliba, Alexander Chen, Matthew McCallum, Katja Culap, Sonja Bernasconi Guastalla, Chiara Silacci-Fregni, Gyorgy Snell, Elisabetta Cameroni, Luca Piccoli, Wesley C. Van Voorhis, Matteo Samuele Pizzuto, Laura E. Rosen, John E. Bowen, Siro Bianchi, Anna De Marco, Stefano Jaconi, Dora Pinto, Maria De Agostini, Giovanni Bona, Kaitlin R. Sprouse, Julia di Iulio, Sasha W Tilles, Davide Corti
Publikováno v:
Science. 373:648-654
SARS-CoV-2 from alpha to epsilon As battles to contain the COVID-19 pandemic continue, attention is focused on emerging variants of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus that have been deemed variants of concern becau
Autor:
Shankar Subramaniam, David Veesler, Lauren Carter, David Novack, Claire Sydeman, Jane Fontenot, Douglas E. Ferrell, Galit Alter, Robbert van der Most, Robert L. Coffman, Elizabeth Kepl, Mary Jane Navarro, Alexander G. White, Ching-Lin Hsieh, Kenneth S. Plante, Francois Villinger, Katharina Röltgen, Prabhu S. Arunachalam, Alexandra C. Walls, Jason S. McLellan, Lisa Shirreff, Rino Rappuoli, Sally Shin, Venkata Viswanadh Edara, Jessica A. Plante, Brooke Fiala, Stephanie Fischinger, Chunfeng Li, Caroline Atyeo, Matthew J. Gorman, Chad J. Roy, Scott D. Boyd, Bali Pulendran, Kasi E. Russell-Lodrigue, Skye Spencer, Xiaoying Shen, Shakti Gupta, Derek T. O'Hagan, Pyone P. Aye, Meera Trisal, Neil P. King, JoAnne L. Flynn, Nadia A. Golden, Marcos C. Miranda, Michael E. P. Murphy, John C. Kraft, Mehul S. Suthar, Lilin Lai, Jason Dufour, Rudolph Bohm, Deleah Pettie, Lara A. Doyle-Meyers, David C. Montefiori, Christopher Monjure, Kenneth A. Rogers, Samuel Wrenn, Harry Kleanthous, Nicholas J. Maness, Jay Rappaport, Alex Lee Zhu, Natalie Brunette
Publikováno v:
Nature. 594:253-258
The development of a portfolio of COVID-19 vaccines to vaccinate the global population remains an urgent public health imperative1. Here we demonstrate the capacity of a subunit vaccine, comprising the SARS-CoV-2 spike protein receptor-binding domain
Autor:
Alexandra C. Walls, Laura A. VanBlargan, Kai Wu, Angela Choi, Mary Jane Navarro, Diana Lee, Laura Avena, Daniela Montes Berrueta, Minh N. Pham, Sayda Elbashir, Marcos C. Miranda, Elizabeth Kepl, Max Johnson, Alyssa Blackstone, Kaitlin Sprouse, Brooke Fiala, Megan A. O’Connor, Natalie Brunette, Prabhu S. Arunachalam, Lisa Shirreff, Kenneth Rogers, Lauren Carter, Deborah H. Fuller, Francois Villinger, Bali Pulendran, Michael S. Diamond, Darin K. Edwards, Neil P. King, David Veesler
The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in 2019 has led to the development of a large number of vaccines, several of which are now approved for use in humans. Understanding vaccine-elicited antibody responses aga
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b41db2620d879ef9b5d36cae1917cb60
https://doi.org/10.1101/2022.02.07.479468
https://doi.org/10.1101/2022.02.07.479468
SARS-CoV-2 breakthrough infections elicit potent, broad, and durable neutralizing antibody responses
Autor:
Alexandra C. Walls, Kaitlin R. Sprouse, John E. Bowen, Anshu Joshi, Nicholas Franko, Mary Jane Navarro, Cameron Stewart, Elisabetta Cameroni, Matthew McCallum, Erin A. Goecker, Emily J. Degli-Angeli, Jenni Logue, Alex Greninger, Davide Corti, Helen Y. Chu, David Veesler
Publikováno v:
Cell
Although infections among vaccinated individuals lead to milder COVID-19 symptoms relative to those in unvaccinated subjects, the specificity and durability of antibody responses elicited by breakthrough cases remain unknown. Here, we demonstrate tha
Autor:
Andrew C. Hunt, James Brett Case, Young-Jun Park, Longxing Cao, Kejia Wu, Alexandra C. Walls, Zhuoming Liu, John E. Bowen, Hsien-Wei Yeh, Shally Saini, Louisa Helms, Yan Ting Zhao, Tien-Ying Hsiang, Tyler N. Starr, Inna Goreshnik, Lisa Kozodoy, Lauren Carter, Rashmi Ravichandran, Lydia B. Green, Wadim L. Matochko, Christy A. Thomson, Bastian Vögeli, Antje Krüger, Laura A. VanBlargan, Rita E. Chen, Baoling Ying, Adam L. Bailey, Natasha M. Kafai, Scott E. Boyken, Ajasja Ljubetič, Natasha Edman, George Ueda, Cameron M. Chow, Max Johnson, Amin Addetia, Mary-Jane Navarro, Nuttada Panpradist, Michael Gale, Benjamin S. Freedman, Jesse D. Bloom, Hannele Ruohola-Baker, Sean P. J. Whelan, Lance Stewart, Michael S. Diamond, David Veesler, Michael C. Jewett, David Baker
Publikováno v:
SCIENCE TRANSLATIONAL MEDICINE
Science translational medicine, vol 14, iss 646
Science translational medicine, vol 14, iss 646
New variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) continue to arise and prolong the coronavirus disease 2019 (COVID-19) pandemic. Here, we used a cell-free expression workflow to rapidly screen and optimize constructs conta
Autor:
Alexandra C, Walls, Kaitlin R, Sprouse, Anshu, Joshi, John E, Bowen, Nicholas, Franko, Mary Jane, Navarro, Cameron, Stewart, Matthew, McCallum, Erin A, Goecker, Emily J, Degli-Angeli, Jenni, Logue, Alex, Greninger, Helen, Chu, David, Veesler
Publikováno v:
bioRxiv
article-version (status) pre
article-version (number) 2
article-version (status) pre
article-version (number) 2
The SARS-CoV-2 Delta variant is currently responsible for most infections worldwide, including among fully vaccinated individuals. Although these latter infections are associated with milder COVID-19 disease relative to unvaccinated subjects, the spe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d14a1cba0915a6004830bc3c605abf49
https://europepmc.org/articles/PMC8687475/
https://europepmc.org/articles/PMC8687475/
Autor:
David Veesler, M. Alejandra Tortorici, Davide Corti, Jessica Bassi, Alessandra Franzetti Pellanda, Matthew McCallum, Katja Culap, Wesley C. Van Voorhis, Amalio Telenti, Siro Bianchi, Christian Saliba, Julia di Iulio, Anna De Marco, Stefano Jaconi, Alexander Chen, John E. Bowen, Christian Garzoni, G. Snell, Luca Piccoli, Sonja Bernasconi Guastalla, Laura E. Rosen, Sasha W Tiles, Giovanni Bona, Matteo Samuele Pizzuto, Elisabetta Cameroni, Alexandra C. Walls, Chiara Silacci-Fregni, Dora Pinto, Herbert W. Virgin, Mary-Jane Navarro, Maria De Agostini
Publikováno v:
bioRxiv
SARS-CoV-2 entry is mediated by the spike (S) glycoprotein which contains the receptor-binding domain (RBD) and the N-terminal domain (NTD) as the two main targets of neutralizing antibodies (Abs). A novel variant of concern (VOC) named CAL.20C (B.1.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed4ef6b9ada5a0870bf569737454f112
https://doi.org/10.1101/2021.03.31.437925
https://doi.org/10.1101/2021.03.31.437925