Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Mary J. Schmidt"'
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism. 1344:201-209
Alteration in energy metabolism of postmenopausal women might be related to the reduction of dehydroepiandrosterone sulfate (DHEAS). DHEA and DHEAS decline with age, leveling at their nadir near menopause. DHEA and DHEAS modulate fatty acid metabolis
Autor:
Evan T. Keller, Thomas C. Havighurst, Austin L. Shug, Stefan Gravenstein, Kit Mui Chiu, Raymond A. Daynes, Mary J. Schmidt
Publikováno v:
Age and ageing. 28(2)
Objectives: L-carnitine and dehydro-epiandrosterone (DHEA) independently promote mitochondrial energy metabolism. We therefore wondered if an age-related deficiency of L-carnitine or DHEA may account for the declining energy metabolism associated wit
Publikováno v:
Life Sciences. 31:2869-2874
A differential distribution of carnitine was found in twelve microdissected areas of the frozen canine brain. The cerebellar cortex showed the highest level of carnitine, while the lowest amounts were found in the hippocampus and pons sections of the
Autor:
Richard E. Dugan, Austin L. Shug, George E. Hoganson, John C.H. Steele, Mary J. Schmidt, Bruce A. Gilles
Publikováno v:
Analytical Biochemistry. 160:275-280
A protocol for the identification and estimation of short-chain esters of carnitine is described; it is useful for the diagnosis of acidemias. By this method, carnitine esters in urine are converted to coenzyme A esters enzymatically with carnitine a
Autor:
Terry D. Oberley, Austin L. Shug, Mary J. Schmidt, John J. Noonan, Sophie Dong, Harold J. Bruyere, Enid F. Gilbert
Publikováno v:
Journal of Applied Toxicology. 8:9-13
Results from this study indicate that caffeine (at an embryotoxic dose equal to the LD40 administered to 3-day chick embryos produced both ultrastructural and functional abnormalities in embryonic cardiac mitochondria. The principal effects of caffei
Publikováno v:
Metabolism: clinical and experimental. 33(4)
The effects of L-carnitine administration on the severity of diabetes were investigated. Serum glucose, free fatty acids (FFA), triglycerides, and ketones from diabetic and normal rats injected for 2 weeks with 3 g/kg/d of either L-carnitine or salin
Publikováno v:
Basic research in cardiology. 79(5)
The metabolic and physiologic differences between low-flow and zero-flow ischemia of varying duration were compared in the isolated perfused rat heart. Hearts subjected to 60 and 90 minutes of zero-flow ischemia recovered less cardiac work than heart