Zobrazeno 1 - 10
of 75
pro vyhledávání: '"Mary J. Heeb"'
Autor:
Mary J. Heeb, José A. Fernández, Atsuki Yamashita, Olivia R. McDowell, Zihan Guo, Laurent O. Mosnier, Hiroshi Deguchi, John H. Griffin
Publikováno v:
Haematologica, Vol 105, Iss 8 (2020)
Externí odkaz:
https://doaj.org/article/522fbfe189c54f1aa4e8bd685221b543
Autor:
José A. Fernández, Mary J. Heeb, Xiao Xu, Itender Singh, Berislav V. Zlokovic, John H. Griffin
Publikováno v:
Haematologica, Vol 94, Iss 12 (2009)
Background The protein C pathway down-regulates thrombin generation and promotes cytoprotection during inflammation and stress. In preclinical studies using models of murine injury (e.g., sepsis and ischemic stroke), murine protein S may be required
Externí odkaz:
https://doaj.org/article/8f0583ba501a47d58a63e85480c5cf03
Autor:
Julia Oto, Álvaro Fernández-Pardo, Pilar Medina, Laura Martos, Manuel Martinez, Montserrat Royo, David Hervás, Silvia Navarro, Mary J. Heeb, Francisco España, César D. Vera-Donoso
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)
Scientific Reports
Scientific Reports
The diagnostic specificity of prostate specific antigen (PSA) is limited. We aimed to characterize eight anti-PSA monoclonal antibodies (mAbs) to assess the prostate cancer (PCa) diagnostic utility of different PSA molecular forms, total (t) and free
Autor:
Ian Dransfield, Nicole D. Barth, Mary J. Heeb, John A. Marwick, Adriano G. Rossi, Andrew J. Gale
Publikováno v:
The Journal of Immunology. 201:2602-2611
Resolution of the inflammatory response requires coordinated regulation of pro- and anti-inflammatory mediator production, together with clearance of recruited inflammatory cells. Many different receptors have been implicated in phagocytosis of apopt
Autor:
John H. Griffin, Zihan Guo, Olivia R. McDowell, Hiroshi Deguchi, José A. Fernández, Atsuki Yamashita, Laurent O. Mosnier, Mary J. Heeb
Publikováno v:
Haematologica
Autor:
Olivia McDowell, Mosnier Laurent O, Hiroshi Deguchi, John H. Griffin, José A. Fernández, Mary J. Heeb, Atsuki Yamashita
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 38
Skeletal muscle myosin was reported by Deguchi et al to promote thrombus formation ex vivo for flowing human whole blood, to support prothrombinase activity in plasma and to promote prothrombin activation by factors (F) Xa and Va in purified systems.
Publikováno v:
The FASEB Journal. 27:2918-2925
Protein S (PS) is a multifunctional plasma protein of the hemostatic and inflammatory pathways, although mechanisms for its regulation are poorly understood. Since certain plasma proteins are regulated through extracellular phosphorylation, we invest
Publikováno v:
Thrombosis and Haemostasis. 109:229-237
SummaryAnticoagulant plasma protein S (PS) is essential for maintaining haemostatic balance. About 2.5% of PS is stored in platelets and released upon platelet stimulation. So far, little is known about the functionality and importance of platelet (p
Autor:
Mary J. Heeb
Publikováno v:
Expert Review of Hematology. 1:9-12
The PROS1 gene codes for the vitaminK-dependent plasma protein, protein S (PS), an essential anticoagulant and multifunctional protein. The association of PS with thrombosis [1] is well established, but the particular anticoagulant activity or activi
Autor:
José A. Fernández, Mary J. Heeb
Publikováno v:
Seminars in Thrombosis and Hemostasis. 33:013-020
Semen coagulation is achieved by a series of biochemical processes designed to protect and guide the sperm during its migration through the female genital tract so that spermatozoa reach the ovum successfully. Thus, semen coagulation promotes fertili