Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Mary J. Freeman"'
Autor:
Arnaud P. J. Giese, Yi-Quan Tang, Ghanshyam P. Sinha, Michael R. Bowl, Adam C. Goldring, Andrew Parker, Mary J. Freeman, Steve D. M. Brown, Saima Riazuddin, Robert Fettiplace, William R. Schafer, Gregory I. Frolenkov, Zubair M. Ahmed
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
Inner ear hair cells detect sound through deflection of stereocilia that harbor mechanically-gated channels. Here the authors show that protein responsible for Usher syndrome, CIB2, interacts with these channels and is essential for their function an
Externí odkaz:
https://doaj.org/article/65c3629626804bdea9661937eb27fcb2
Autor:
A Catalina Vélez-Ortega, Mary J Freeman, Artur A Indzhykulian, Jonathan M Grossheim, Gregory I Frolenkov
Publikováno v:
eLife, Vol 6 (2017)
Mechanotransducer channels at the tips of sensory stereocilia of inner ear hair cells are gated by the tension of 'tip links' interconnecting stereocilia. To ensure maximal sensitivity, tip links are tensioned at rest, resulting in a continuous influ
Externí odkaz:
https://doaj.org/article/6b40637b5dc84d4c8a686f5c61ecafd7
Autor:
A. Catalina Vélez-Ortega, Gregory I. Frolenkov, Artur A. Indzhykulian, Jonathan M Grossheim, Mary J Freeman
Publikováno v:
eLife
eLife, Vol 6 (2017)
eLife, Vol 6 (2017)
Mechanotransducer channels at the tips of sensory stereocilia of inner ear hair cells are gated by the tension of 'tip links' interconnecting stereocilia. To ensure maximal sensitivity, tip links are tensioned at rest, resulting in a continuous influ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46db4ba6a644280aa803c424475439b4
https://pubmed.ncbi.nlm.nih.gov/28350294
https://pubmed.ncbi.nlm.nih.gov/28350294
Autor:
Zubair M. Ahmed, Adam C. Goldring, Ghanshyam P. Sinha, Michael R. Bowl, Saima Riazuddin, Gregory I. Frolenkov, Mary J Freeman, Andrew Parker, Robert Fettiplace, Yi-Quan Tang, Steve D.M. Brown, William R Schafer, Arnaud P. J. Giese
Publikováno v:
Nature Communications
Nature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
Nature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
Inner ear hair cells detect sound through deflection of stereocilia, the microvilli-like projections that are arranged in rows of graded heights. Calcium and integrin-binding protein 2 is essential for hearing and localizes to stereocilia, but its ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6214b6dbcf09a3d5d695f8b9f434e7f3
https://pubmed.ncbi.nlm.nih.gov/28663585
https://pubmed.ncbi.nlm.nih.gov/28663585