Zobrazeno 1 - 10
of 64
pro vyhledávání: '"Mary J. Druse"'
Publikováno v:
Brain Research. 1383:13-21
This laboratory showed that ethanol augments apoptosis in fetal rhombencephalic neurons and co-treatment with alpha-lipoic acid (LA) or one of several other antioxidants prevents ethanol-associated apoptosis. Because ethanol increases oxidative stres
Autor:
Mary J. Druse, Angeline M. Antonio
Publikováno v:
Brain Research. 1204:16-23
It is well known that ethanol damages the developing nervous system by augmenting apoptosis. Previously, this laboratory reported that ethanol augments apoptosis in fetal rhombencephalic neurons, and that the increased apoptosis is associated with re
Publikováno v:
Alcohol. 29:157-164
Previously, results of studies from our laboratory have shown that the offspring of ethanol-fed female rats have a significant decrease in serotonin (5-HT) neurons and glia that contain S100B, an essential trophic factor for the development of 5-HT n
Autor:
Mary J. Druse, James M. Woods
Publikováno v:
Journal of Neurochemistry. 66:2168-2178
This study examined the hypothesis that chronic ethanol consumption results in significant abnormalities in both the dopaminergic and the serotonergic system of aged rats. Levels of dopamine (DA), serotonin [5-hydroxytryptamine (5-HT)], 3,4-dihydroxy
Publikováno v:
Developmental Brain Research. 121:133-143
This laboratory previously showed that in utero ethanol exposure severely impairs the development of the cell bodies and projections of serotonin (5-HT) neurons, and that maternal treatment with a 5-HT(1A) agonist prevents many of these abnormalities
Publikováno v:
Alcoholism: Clinical and Experimental Research. 23:1519-1527
Background: One of the effects of fetal alcohol syndrome (FAS) is altered motor function. In an attempt to elucidate a potential cause of this ethanol-associated damage, we investigated the effects of in utero ethanol exposure on the production of pr
Publikováno v:
Alcoholism: Clinical and Experimental Research. 21:1157-1164
The serotonergic system in brain is adversely affected by both aging and chronic ethanol consumption. The present study examined the combined effects of aging and chronic ethanol consumption on two components of the serotonergic system. Serotonin (5-
Publikováno v:
Alcoholism: Clinical and Experimental Research. 21:1169-1178
In utero ethanol exposure results in a decreased concentration of serotonin (5-HT) in brain regions containing the cell bodies of 5-HT neurons and their cortical projections. The concentration of 5-HT reuptake sites is also reduced in several brain a
Publikováno v:
Alcoholism: Clinical and Experimental Research. 21:452-459
Previously, it was shown that in utero ethanol exposure results in decreased serotonin (5-HT) and altered concentrations of 5-HT reuptake sites and 5-HT 1A receptors in fetal and/or postnatal rats. Because fetal 5-HT is an essential trophic factor, t
Publikováno v:
Behavioural Brain Research. 73:19-29