Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Mary J. Castillo"'
Autor:
Mark R. Charbonneau, William S. Denney, Nicholas G. Horvath, Pasquale Cantarella, Mary J. Castillo, Marja K. Puurunen, Aoife M. Brennan
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-12 (2021)
Mark Charbonneau et al. develop a mathematical model that describes the behavior of an engineered bacterial therapeutic, SYNB1618, in the human gastrointestinal tract and its effects on plasma phenylalanine (Phe) levels. This model enables the author
Externí odkaz:
https://doaj.org/article/9c842b6d19dd4ea5ab162237138ababd
Autor:
M. Tyler Nelson, Mark R. Charbonneau, Heidi G. Coia, Mary J. Castillo, Corey Holt, Eric S. Greenwood, Peter J. Robinson, Elaine A. Merrill, David Lubkowicz, Camilla A. Mauzy
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Engineered live bacteria could represent a new class of therapeutic treatment for human disease. Here, the authors use a human gut-on-a-chip microfluidics system to characterize an engineered live bacterial therapeutic, designed for the treatment of
Externí odkaz:
https://doaj.org/article/229bd7533d5f4591b5fea3903111b0fd
Autor:
Marja K. Puurunen, Jerry Vockley, Shawn L. Searle, Stephanie J. Sacharow, John A. Phillips, William S. Denney, Benjamin D. Goodlett, David A. Wagner, Larry Blankstein, Mary J. Castillo, Mark R. Charbonneau, Vincent M. Isabella, Vasu V. Sethuraman, Richard J. Riese, Caroline B. Kurtz, Aoife M. Brennan
Publikováno v:
Nature Metabolism. 4:1214-1214
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::05de650ff6c47d4b608240b7940f8363
https://doi.org/10.1038/s42255-022-00635-4
https://doi.org/10.1038/s42255-022-00635-4
Autor:
Marja K, Puurunen, Jerry, Vockley, Shawn L, Searle, Stephanie J, Sacharow, John A, Phillips, William S, Denney, Benjamin D, Goodlett, David A, Wagner, Larry, Blankstein, Mary J, Castillo, Mark R, Charbonneau, Vincent M, Isabella, Vasu V, Sethuraman, Richard J, Riese, Caroline B, Kurtz, Aoife M, Brennan
Publikováno v:
Nature metabolism. 3(8)
Phenylketonuria (PKU) is a rare disease caused by biallelic mutations in the PAH gene that result in an inability to convert phenylalanine (Phe) to tyrosine, elevated blood Phe levels and severe neurological complications if untreated. Most patients
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f82627a32b8de2935eacdf630d65bebf
https://pubmed.ncbi.nlm.nih.gov/35974248
https://pubmed.ncbi.nlm.nih.gov/35974248