Zobrazeno 1 - 10
of 218
pro vyhledávání: '"Mary J, Laughlin"'
Autor:
Jeong-su Do, Daniel Zwick, Jonathan D. Kenyon, Fei Zhong, David Askew, Alex Y. Huang, Wouter Van’t Hof, Marcie Finney, Mary J. Laughlin
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Abstract The key obstacle to clinical application of human inducible regulatory T cells (iTreg) as an adoptive cell therapy in autoimmune disorders is loss of FOXP3 expression in an inflammatory milieu. Here we report human iTreg co-cultured with bon
Externí odkaz:
https://doaj.org/article/24468a2c65444254ba3db5b26d183319
Autor:
Samantha H. Chiang, Gerald A. Thomas, Wei Liao, Tristan Grogan, Robert L. Buck, Laurel Fuentes, Maha Yakob, Mary J. Laughlin, Chris Schafer, Abu Nazmul-Hossain, Fang Wei, David Elashoff, Paul D. Slowey, David T.W. Wong
Publikováno v:
BioTechniques, Vol 58, Iss 2, Pp 69-76 (2015)
The stabilization and processing of salivary transcriptome and proteome biomarkers is a critical challenge due to the ubiquitous nature of nucleases and proteases as well as the inherent instability of these biomarkers. Furthermore, extension of sali
Externí odkaz:
https://doaj.org/article/21cdb4e435594ca5a802cf84b8029a83
Autor:
Srinivasa R Nagalla, Caryn K Snyder, John E Michaels, Mary J Laughlin, Charles T Roberts, Madhuri Balaji, V Balaji, V Seshiah, Paturi V Rao
Publikováno v:
Indian Journal of Endocrinology and Metabolism, Vol 19, Iss 1, Pp 155-159 (2015)
The prevalence of gestational diabetes mellitus (GDM) is increasing because of the worldwide obesity/diabetes epidemic. The complications of untreated GDM affect both the mother and baby and include complications during pregnancy as well as increased
Externí odkaz:
https://doaj.org/article/abd06b98de0d4789bed9c079210b28d3
Autor:
Olga Miočević, Craig R. Cole, Mary J. Laughlin, Robert L. Buck, Paul D. Slowey, Elizabeth A. Shirtcliff
Publikováno v:
Frontiers in Public Health, Vol 5 (2017)
Saliva is an emerging biofluid with a significant number of applications in use across research and clinical settings. The present paper explores the reasons why saliva has grown in popularity in recent years, balancing both the potential strengths a
Externí odkaz:
https://doaj.org/article/a4256532e17c4360991ee28ab3a5e9ca
Autor:
Marcelo C. Pasquini, Alok Srivastava, Syed Osman Ahmed, Mahmoud Aljurf, Yoshiko Atsuta, Carol Doleysh, Sebastian Galeano, Eliane Gluckman, Hildegard Greinix, Gregory Hale, Parameswaran Hari, Shahrukh K. Hashmi, Naynesh Kamani, Mary J. Laughlin, Dietger Niederwieser, Adriana Seber, Jeffrey Szer, John A. Snowden, Koen Van Biesen, Paula Watry, Daniel J. Weisdorf, Jane Apperley
Publikováno v:
Hematology/Oncology and Stem Cell Therapy, Vol 13, Iss 3, Pp 131-142 (2020)
Hematol Oncol Stem Cell Ther
Hematol Oncol Stem Cell Ther
Hematopoietic cell transplantation (HCT) is a highly complex procedure that requires a dedicated multidisciplinary team to optimize its safety. In addition, institutions may have different needs regarding indications based on regional disease prevale
Autor:
Adriana Seber, Mary J. Laughlin, Koen Van Biesen, Gregory A. Hale, Naynesh Kamani, Eliane Gluckman, Sebastian Galeano, Shahrukh K. Hashmi, Syed Osman Ahmed, Jeff Szer, Paula Watry, Alok Srivastava, Yoshiko Atsuta, Daniel J. Weisdorf, Parameswaran Hari, Mahmoud Aljurf, John A. Snowden, Hildegard T. Greinix, Dietger Niederwieser, Marcelo C. Pasquini, Carol Doleysh, Jane F. Apperley
Publikováno v:
Biology of Blood and Marrow Transplantation. 25:2322-2329
Hematopoietic cell transplantation (HCT) is a highly complex procedure that requires a dedicated multidisciplinary team to optimize safety. In addition, institutions may have different needs regarding indications based on regional disease prevalence
Autor:
Mary J. Laughlin, Alex Yee-Chen Huang, Jeong-su Do, Marcie Finney, Daniel Zwick, Fei Zhong, Jonathan D. Kenyon, Wouter Van’t Hof, David Askew
Publikováno v:
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
The key obstacle to clinical application of human inducible regulatory T cells (iTreg) as an adoptive cell therapy in autoimmune disorders is loss of FOXP3 expression in an inflammatory milieu. Here we report human iTreg co-cultured with bone marrow-
Autor:
Marcie Finney, Kathy Bobik-Kurz, JoAnn Chase, Sue Boucher, Candice Laster, Bridget Wood, Dawn Thut, Faith Dedino, Angela Alemany, Sara Shields, Kim Vincent, Denise DiNello, Michelle Adamo, Kara Evans, Molly Walker, Wouter Van’t Hof, Mary J. Laughlin
Publikováno v:
Transplantation and Cellular Therapy. 28:S261
Autor:
Wouter Van’t Hof, Fei Zhong, Mary J. Laughlin, Jeong su Do, Marcie Finney, Alex Yee-Chen Huang
Publikováno v:
Bone Marrow Transplantation. 53:1568-1577
Foxp3 is essential for T regulatory cell (Treg) function. Broad complex-Tramtrack-Bric-a-brac domain (BTB) and Cap'n'collar (CNC) homology 1, transcription factor 2 (BACH2) stabilizes Treg immune homeostasis in murine studies. However, little is know
Autor:
Sid Ganguly, Soumen Paul, Joseph McGuirk, Jonathan D. Mahnken, Brea Lipe, Maegan L. Capitano, Dennis Allin, Hal E. Broxmeyer, Amanda L. Wise, Leyla Shune, Anurag K. Singh, Sunil Abhyankar, Abigale Berry, George A. Vielhauer, Mary J. Laughlin, Omar S. Aljitawi, Christopher Lominska, Tara L. Lin, Avishek Ganguly, Amy Cantilena
Publikováno v:
Blood. 128:3000-3010
Umbilical cord blood (UCB) engraftment is in part limited by graft cell dose, generally one log less than that of bone marrow (BM)/peripheral blood (PB) cell grafts. Strategies toward increasing hematopoietic stem/progenitor cell (HSPC) homing to BM