Zobrazeno 1 - 10
of 81
pro vyhledávání: '"Mary J, Cloninger"'
Autor:
Samuel P. Bernhard, Candace K. Goodman, Erienne G. Norton, Daniel G. Alme, C. Martin Lawrence, Mary J. Cloninger
Publikováno v:
ACS Omega, Vol 5, Iss 45, Pp 29017-29024 (2020)
Externí odkaz:
https://doaj.org/article/9a92689ddf424a80926fc40ba58c864d
Publikováno v:
Biomacromolecules. 22:4720-4729
Galectins are galactoside-binding lectins that are functional dimers or higher-order oligomers. Multivalent binding has been shown to augment the relatively low affinity of the galectins for their galactoside-binding partners, enabling the galectins
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5d750c2705108358550647fe38ecfad5
https://doi.org/10.1021/acs.biomac.1c01001
https://doi.org/10.1021/acs.biomac.1c01001
Autor:
Jonathan M. Cousin, Mary J. Cloninger
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 11, Iss 1, Pp 739-747 (2015)
Four generations of lactose-functionalized polyamidoamine (PAMAM) were employed to further the understanding of multivalent galectin-1 mediated interactions. Dynamic light scattering and fluorescence microscopy were used to study the multivalent inte
Externí odkaz:
https://doaj.org/article/082c96d7cdb04e7c8d7e79cbdbed0649
Autor:
Candace K. Goodman, Mark L. Wolfenden, Pratima Nangia-Makker, Anna K. Michel, Avraham Raz, Mary J. Cloninger
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 10, Iss 1, Pp 1570-1577 (2014)
Galectin-3 meditates cell surface glycoprotein clustering, cross linking, and lattice formation. In cancer biology, galectin-3 has been reported to play a role in aggregation processes that lead to tumor embolization and survival. Here, we show that
Externí odkaz:
https://doaj.org/article/101ee4bc6e374085b2137a5753615f72
Autor:
Michelle L Aries, Mary J. Cloninger
Publikováno v:
Metabolomics
INTRODUCTION: Multivalent antimicrobial dendrimers are an exciting new system that is being developed to address the growing problem of drug resistant bacteria. Nuclear Magnetic Resonance (NMR) metabolomics is a quantitative and reproducible method f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3cb023031d77a7ee5b2fcbe969125b7b
https://doi.org/10.1007/s11306-020-01702-1
https://doi.org/10.1007/s11306-020-01702-1
Publikováno v:
Polym Chem
Dendritic polyglycerols (dPGs) are emerging as important polymers for the study of biological processes due to their relatively low toxicity and excellent biocompatibility. The highly branched nature and high density of endgroups make the dPGs partic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2dacb1c794564bb61f4f21fd277bb43
https://europepmc.org/articles/PMC8881006/
https://europepmc.org/articles/PMC8881006/
Autor:
Michelle L. Aries, Mary J. Cloninger
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences; Volume 22; Issue 24; Pages: 13606
International Journal of Molecular Sciences, Vol 22, Iss 13606, p 13606 (2021)
International Journal of Molecular Sciences; Volume 22; Issue 24; Pages: 13606
International Journal of Molecular Sciences, Vol 22, Iss 13606, p 13606 (2021)
Multivalent membrane disruptors are a relatively new antimicrobial scaffold that are difficult for bacteria to develop resistance to and can act on both Gram-positive and Gram-negative bacteria. Proton Nuclear Magnetic Resonance (1H NMR) metabolomics
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0abbd07b28bbe4be0c88182f7c8798b5
https://doi.org/10.3390/ijms222413606
https://doi.org/10.3390/ijms222413606
Autor:
Jessica H. Ennist, Henry R Termuehlen, Samuel P. Bernhard, Mackenzie S. Fricke, Mary J. Cloninger
Publikováno v:
Bioconjug Chem
Chemoenzymatic synthesis is an important strategy for the formation of glycopolymers. The use of a smaller number of traditional chemical steps and enzyme catalyzed reactions increases the yield of glycopolymer that can be produced by reducing the ov
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d3ecbb90d33f9cbf14b7b725233d154
https://pubmed.ncbi.nlm.nih.gov/30372040
https://pubmed.ncbi.nlm.nih.gov/30372040
Autor:
Mary J. Cloninger, Jonathan M. Cousin
Publikováno v:
Beilstein Journal of Organic Chemistry
Beilstein Journal of Organic Chemistry, Vol 11, Iss 1, Pp 739-747 (2015)
Beilstein Journal of Organic Chemistry, Vol 11, Iss 1, Pp 739-747 (2015)
Four generations of lactose-functionalized polyamidoamine (PAMAM) were employed to further the understanding of multivalent galectin-1 mediated interactions. Dynamic light scattering and fluorescence microscopy were used to study the multivalent inte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e2e653545d05635a8add5d97be22616
https://doi.org/10.3762/bjoc.11.84
https://doi.org/10.3762/bjoc.11.84
Publikováno v:
ChemBioChem. 15:2106-2112
By using lactose-functionalized poly(amidoamine) dendrimers as a tunable multivalent platform, we studied cancer cell aggregation in three different cell lines (A549, DU-145, and HT-1080) with galectin-3. We found that small lactose-functionalized G(
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0279c24f0b867ce951a660355cb40de9
https://doi.org/10.1002/cbic.201402134
https://doi.org/10.1002/cbic.201402134