Cancer Moonshot Immuno-Oncology Translational Network (IOTN): accelerating the clinical translation of basic discoveries for improving immunotherapy and immunoprevention of cancer

Autor: Lawrence Fong, Song Liu, Eliezer Van Allen, Yi Xing, Ananth Annapragada, Andrew Sikora, Catherine Bollard, Jose Conejo-Garcia, Conrad Russell Cruz, Shadmehr Demehri, Michael Demetriou, Levon Demirdjian, Mary Horowitz, Alan Hutson, Kathryn Kadash-Edmondson, Donald Kufe, Steven Lipkin, Claire McCarthy, Martin Morgan, Zachary Morris, Yang Pan, Marcelo Pasquini, Stephen Schoenberger, Eduardo Vilar, Wenjuan Zha, Adekunle Odunsi

Publikováno v: Journal for ImmunoTherapy of Cancer, Vol 8, Iss 1 (2020)

Despite regulatory approval of several immune-based treatments for cancer in the past decade, a number of barriers remain to be addressed in order to fully harness the therapeutic potential of the immune system and provide benefits for patients with

Externí odkaz: https://doaj.org/article/f6e5a2f33b5f41c4abd3518e187f2e5c

Upper gastrointestinal acute graft-versus-host disease adds minimal prognostic value in isolation or with other graft-versus-host disease symptoms as currently diagnosed and treated

Autor: Sarah Nikiforow, Tao Wang, Michael Hemmer, Stephen Spellman, Görgün Akpek, Joseph H. Antin, Sung Won Choi, Yoshihiro Inamoto, Hanna J. Khoury, Margaret MacMillan, David I. Marks, Ken Meehan, Hideki Nakasone, Taiga Nishihori, Richard Olsson, Sophie Paczesny, Donna Przepiorka, Vijay Reddy, Ran Reshef, Hélène Schoemans, Ned Waller, Daniel Weisdorf, Baldeep Wirk, Mary Horowitz, Amin Alousi, Daniel Couriel, Joseph Pidala, Mukta Arora, Corey Cutler

Publikováno v: Haematologica, Vol 103, Iss 10 (2018)

Upper gastrointestinal acute graft-versus-host disease is reported in approximately 30% of hematopoietic stem cell transplant recipients developing acute graft-versus-host disease. Currently classified as Grade II in consensus criteria, upper gastroi

Externí odkaz: https://doaj.org/article/df31b72bf7b04b0ab0d224f947ea1a11

Bringing Patient and Caregivers Voices to the Clinical Trial Chorus: A Report From the BMT CTN Patient and Caregiver Advocacy Task Force

Autor: Sumithira Vasu, Shernan G. Holtan, Akiko Shimamura, Todd Burnworth, Shauna Whisenton, Sanderson Adams, Brandon Nuechterlein, Nicole Mortier, Jackie Foster, Nancy DiFronzo, Mary Horowitz, Doug Rizzo, Amy Foley

Publikováno v: Transplantation and Cellular Therapy. 29:5-9

The Blood and Marrow Transplant Clinical Trials Network (BMT CTN), funded by the National Heart, Lung, and Blood Institute and the National Cancer Institute for more than 2 decades, is focused on improving the outcomes of hematopoietic cell transplan

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::254528cce946fcd75ffa29252274b5ce
https://doi.org/10.1016/j.jtct.2022.10.016

Reaching beyond maximum grade: progress and future directions for modernising the assessment and reporting of adverse events in haematological malignancies

Autor: Gita Thanarajasingam, Lori M Minasian, Vishal Bhatnagar, Franco Cavalli, R Angelo De Claro, Amylou C Dueck, Tarec C El-Galaly, Neil Everest, Jan Geissler, Christian Gisselbrecht, Nicole Gormley, John Gribben, Mary Horowitz, S Percy Ivy, Caron A Jacobson, Armand Keating, Paul G Kluetz, Yok Lam Kwong, Richard F Little, Matthew J Matasar, Maria-Victoria Mateos, Kristen McCullough, Robert S Miller, Mohamad Mohty, Philippe Moreau, Lindsay M Morton, Sumimasa Nagai, Abhilasha Nair, Loretta Nastoupil, Kaye Robertson, Surbhi Sidana, Karin E Smedby, Pieter Sonneveld, Kyriaki Tzogani, Flora E van Leeuwen, Galina Velikova, Diego Villa, John R Wingard, John F Seymour, Thomas M Habermann

Publikováno v: Thanarajasingam, G, Minasian, L M, Bhatnagar, V, Cavalli, F, De Claro, R A, Dueck, A C, El-Galaly, T C, Everest, N, Geissler, J, Gisselbrecht, C, Gormley, N, Gribben, J, Horowitz, M, Ivy, S P, Jacobson, C A, Keating, A, Kluetz, P G, Kwong, Y L, Little, R F, Matasar, M J, Mateos, M-V, McCullough, K, Miller, R S, Mohty, M, Moreau, P, Morton, L M, Nagai, S, Nair, A, Nastoupil, L, Robertson, K, Sidana, S, Smedby, K E, Sonneveld, P, Tzogani, K, van Leeuwen, F E, Velikova, G, Villa, D, Wingard, J R, Seymour, J F & Habermann, T M 2022, ' Reaching beyond maximum grade : progress and future directions for modernising the assessment and reporting of adverse events in haematological malignancies ', The Lancet. Haematology, vol. 9, no. 5, pp. e374-e384 . https://doi.org/10.1016/S2352-3026(22)00045-X
Lancet Haematol

Remarkable improvements in outcomes for many haematological malignancies have been driven primarily by a proliferation of novel therapeutics over the past two decades. Targeted agents, immune and cellular therapies, and combination regimens have adve

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2405df3e3651e395b828efbe04d1d737
https://doi.org/10.1016/s2352-3026(22)00045-x

Updated Trends in Hematopoietic Cell Transplantation in the United States with an Additional Focus on Adolescent and Young Adult Transplantation Activity and Outcomes

Autor: Rachel Phelan, Min Chen, Caitrin Bupp, Yung-Tsi Bolon, Larisa Broglie, Janet Brunner-Grady, Linda J. Burns, Saurabh Chhabra, Debra Christianson, Rachel Cusatis, Steven M. Devine, Anita D'Souza, Mary Eapen, Mehdi Hamadani, Mary Hengen, Stephanie J. Lee, Amy Moskop, Kristin M. Page, Marcelo Pasquini, Waleska S. Pérez, Marcie Riches, Doug Rizzo, Wael Saber, Stephen R. Spellman, Heather E. Stefanski, Patricia Steinert, Daniel Weisdorf, Mary Horowitz, Jeffery J. Auletta, Bronwen E. Shaw, Mukta Arora

Publikováno v: Transplant Cell Ther

Hematopoietic cell transplantation (HCT) has been successfully utilized as treatment for many malignant and non-malignant conditions. As supportive care, donor selection, and treatment modalities evolve, documenting HCT trends and outcomes is critica

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eaf19d53c32a84934c6e77fb676236ff
https://pubmed.ncbi.nlm.nih.gov/35447374