Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Mary H. Y. Tang"'
Autor:
Gordon K C Leung, Christopher C Y Mak, Jasmine L F Fung, Wilfred H S Wong, Mandy H Y Tsang, Mullin H C Yu, Steven L C Pei, K S Yeung, Gary T K Mok, C P Lee, Amelia P W Hui, Mary H Y Tang, Kelvin Y K Chan, Anthony P Y Liu, Wanling Yang, P C Sham, Anita S Y Kan, Brian H Y Chung
Publikováno v:
BMC Medical Genomics, Vol 11, Iss 1, Pp 1-10 (2018)
Abstract Background Whole-exome sequencing (WES) has become an invaluable tool for genetic diagnosis in paediatrics. However, it has not been widely adopted in the prenatal setting. This study evaluated the use of WES in prenatal genetic diagnosis in
Externí odkaz:
https://doaj.org/article/282d5793434f48b0ae2433ea3829b919
Publikováno v:
Prenatal Diagnosis. 42:1155-1161
To review prenatal diagnosis and outcome of alpha thalassaemia major through universal antenatal screening.This was a retrospective study on ultrasound features, antenatal diagnosis, in-utero intervention and long term outcome of pregnancies at risk
Publikováno v:
Prenatal Diagnosis. 42
Autor:
Anita S Y Kan, Elizabeth T Lau, W F Tang, Sario S Y Chan, Simon C K Ding, Kelvin Y K Chan, C P Lee, Pui Wah Hui, Brian H Y Chung, K Y Leung, Teresa Ma, Wing C Leung, Mary H Y Tang
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e87988 (2014)
OBJECTIVE: To evaluate the effectiveness of whole-genome array comparative genomic hybridization (aCGH) in prenatal diagnosis in Hong Kong. METHODS: Array CGH was performed on 220 samples recruited prospectively as the first-tier test study. In addit
Externí odkaz:
https://doaj.org/article/48ea845e986b4bd1bb68f78622079203
Autor:
Stephanie C Y Yu, Peiyong Jiang, Kwong W Choy, Kwan Chee Allen Chan, Hye-Sung Won, Wing C Leung, Elizabeth T Lau, Mary H Y Tang, Tak Y Leung, Yuk Ming Dennis Lo, Rossa W K Chiu
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e60968 (2013)
Fetal DNA is present in the plasma of pregnant women. Massively parallel sequencing of maternal plasma DNA has been used to detect fetal trisomies 21, 18, 13 and selected sex chromosomal aneuploidies noninvasively. Case reports describing the detecti
Externí odkaz:
https://doaj.org/article/77fbd4bbe1214d09b32d4f0442e0c19b
Noninvasive prenatal diagnosis of fetal trisomy 18 and trisomy 13 by maternal plasma DNA sequencing.
Autor:
Eric Z Chen, Rossa W K Chiu, Hao Sun, Ranjit Akolekar, K C Allen Chan, Tak Y Leung, Peiyong Jiang, Yama W L Zheng, Fiona M F Lun, Lisa Y S Chan, Yongjie Jin, Attie T J I Go, Elizabeth T Lau, William W K To, Wing C Leung, Rebecca Y K Tang, Sidney K C Au-Yeung, Helena Lam, Yu Y Kung, Xiuqing Zhang, John M G van Vugt, Ryoko Minekawa, Mary H Y Tang, Jun Wang, Cees B M Oudejans, Tze K Lau, Kypros H Nicolaides, Y M Dennis Lo
Publikováno v:
PLoS ONE, Vol 6, Iss 7, p e21791 (2011)
Massively parallel sequencing of DNA molecules in the plasma of pregnant women has been shown to allow accurate and noninvasive prenatal detection of fetal trisomy 21. However, whether the sequencing approach is as accurate for the noninvasive prenat
Externí odkaz:
https://doaj.org/article/79bcfe2a4cb842b498a88221fab38ddf
Autor:
Dana W Y Tsui, Y M Doris Lam, Wing S Lee, Tak Y Leung, Tze K Lau, Elizabeth T Lau, Mary H Y Tang, Ranjit Akolekar, Kypros H Nicolaides, Rossa W K Chiu, Y M Dennis Lo, Stephen S C Chim
Publikováno v:
PLoS ONE, Vol 5, Iss 11, p e15069 (2010)
BACKGROUND: Noninvasive prenatal diagnosis of fetal aneuploidy by maternal plasma analysis is challenging owing to the low fractional and absolute concentrations of fetal DNA in maternal plasma. Previously, we demonstrated for the first time that fet
Externí odkaz:
https://doaj.org/article/7d90812ce3f54b7d970b0abfb0cce9a4
Autor:
Patrick K C, Au, Yvonne K Y, Kwok, K Y, Leung, Linda Y F, Tang, Mary H Y, Tang, Elizabeth T, Lau
Publikováno v:
Prenatal diagnosis. 31(2)
Autor:
Paulina P Y, Ng, Mary H Y, Tang, Elizabeth T, Lau, Lucy K L, Ng, Ernest H Y, Ng, P C, Tam, William S B, Yeung, P C, Ho
Publikováno v:
Hong Kong medical journal = Xianggang yi xue za zhi. 15(1)
To report the type and frequency of chromosomal anomalies and Y-microdeletions among Hong Kong Chinese subfertile men with sperm concentrations lower than 5 million/mL. DESIGN. Retrospective study.A reproductive centre in Hong Kong.A total of 295 Chi
Autor:
W C, Leung, E T, Lau, W L, Lau, Rebecca, Tang, Shell Fean, Wong, T K, Lau, K T, Tse, S F, Wong, W K, To, Lucy K L, Ng, T T, Lao, Mary H Y, Tang
Publikováno v:
Hong Kong medical journal = Xianggang yi xue za zhi. 14(1)
The application of rapid aneuploidy testing as a stand-alone approach in prenatal diagnosis is much debated. The major criticism of this targeted approach is that it will not detect other chromosomal abnormalities that will be picked up by traditiona