Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Mary H. H. Chandler"'
Publikováno v:
Europe PubMed Central
The predictive performance of Bayesian estimates incorporating pharmacokinetic values for hematology-oncology patients was compared with that of Bayesian estimates incorporating general population values. In study phase 1, medical records were review
Autor:
Mary H. H. Chandler, George A. Davis
Publikováno v:
Oral and Maxillofacial Surgery Clinics of North America. 8:245-263
SUMMARY Elders represent a growing population in the health-care system and can present with multiple chronic diseases that are managed with drug therapy. The oral and maxillofacial surgeon should be aware of the uniqueness of the geriatric patient a
Publikováno v:
Obstetrics & Gynecology. 86:78-84
Objective To use a novel, sensitive study design to detect a potential oral contraceptive (OC) and dirithromycin drug interaction by assessing the pharmacokinetics of the ethinyl estradiol (E2) component of a common OC and the potential failure of OC
Publikováno v:
American Journal of Health-System Pharmacy. 51:2125-2130
The Cockcroft-Gault and Salazar-Corcoran equations were compared with respect to prediction of gentamicin pharmacokinetic values in obese and nonobese patients, and the results were used to formulate guidelines for calculating initial gentamicin dosa
Publikováno v:
Europe PubMed Central
Publikováno v:
Therapeutic Drug Monitoring. 15:427-430
The influence of serum separator tubes (SSTs) on total and free phenytoin concentrations and phenytoin dosages was evaluated in patients treated with phenytoin. Thirty blood samples were obtained from 18 patients. Equal volumes of blood were placed i
Publikováno v:
Clinical Pharmacokinetics. 25:205-216
Over the past 20 years, pharmacokinetic programs have been developed for clinical decision making. These clinical pharmacokinetic software programs are designed to assist the clinician in the analysis, interpretation and reporting of serum drug conce
Publikováno v:
British Journal of Clinical Pharmacology. 32:735-739
1. The disposition of hexobarbitone enantiomers before and after rifampicin treatment (600 mg daily for 14 days) was investigated in six young (29 +/- 3 years old) and six elderly (71 +/- 4 years old) healthy male volunteers. Hexobarbitone was given
Publikováno v:
The Journal of Clinical Pharmacology. 30:330-335
This clinical investigation was designed to characterize the pharmacologic response to theophylline in elderly individuals. Incremental theophylline plasma concentrations (0, 5, 10, 15, and 20 mcg/mL), achieved through dose escalation of intravenous
Autor:
Julie K. Birt, Mary H. H. Chandler
Publikováno v:
Therapeutic Drug Monitoring. 12:206-209
The serum concentrations and pharmacokinetic parameters produced from standard doses of vancomycin were evaluated in 22 patients. The mean (\pmSD) half-life, clearance (CI), and volume of distribution, respectively, were 6.2 (\pm1.9) h, 79.2 (\pm34.3