Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Mary G. Murphy"'
Autor:
Patrick A. O'Regan, Mary G. Murphy, Laurette Geldenhuys, Philip D. Acott, Mustafa Al-Khalidi, Jacqueline Upham, John F. S. Crocker
Publikováno v:
Journal of Toxicology and Environmental Health, Part A. 70:1772-1775
Young mice exposed dermally to the Toximul (Tox) class of agricultural pesticide adjuvants have reduced levels of hepatic glycogen, a marker of subclinical toxicity. The present study determined whether these effects on glycogen also occurred in cult
Autor:
Christopher J. Sinal, Philip D. Acott, Jacqueline Upham, John F. S. Crocker, Laurette Geldenhuys, Mary G. Murphy, Patrick A. O'Regan
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 1772(9):1057-1064
Previous studies demonstrated that chronic dermal exposure to the pesticide adjuvant (surfactant), Toximul (Tox), has significant detrimental effects on hepatic lipid metabolism. This study demonstrated that young mice dermally exposed to Tox for 12
Autor:
Mary G. Murphy
Publikováno v:
Journal of Neurochemistry. 47:245-253
The role of membrane polyunsaturated fatty acids (PUFAs) in the regulation of basal adenylate cyclase activity was examined in intact N1E-115 neuroblastoma cells. Addition of linoleic acid (50 microM) to the culture medium for 48 h resulted in a sign
Autor:
J.F.S. Crocker, Spencer H. S. Lee, Mary G. Murphy, Mustafa Al-Khalidi, P. O’Regan, Philip D. Acott
Publikováno v:
Chemosphere. 59:235-246
Previous studies demonstrated that young mice exposed chronically to industrial surfactant (IS) do not exhibit obvious adverse health effects, but do have persistently reduced body weights and compromised hepatic energy metabolism. The present study
Autor:
Mary G. Murphy, Philip D. Acott, K R Rozee, John F. S. Crocker, D. Gough, J. MacDonald, J. Evans, Spencer H. S. Lee
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 1637(3):183-186
Antibodies to cardiolipin (aCLA), a phospholipid primarily localized in inner mitochondrial membranes, were transiently elevated (P
Autor:
Heather Layton, Laura K. Cole, Jonathan M. Curtis, Jaroslav A. Kralovec, H. Stephen Ewart, Mary G. Murphy, Jeffrey L. C. Wright
Publikováno v:
The Journal of Nutrition. 132:1149-1152
This study was designed to investigate the lipid-lowering ability of a novel dietary ingredient composed of phytosterols esterified to (n-3) polyunsaturated fatty acids (PUFA) [PS(n-3)]. Adult guinea pigs were fed a test diet supplemented with PS(n-3
Publikováno v:
Cardiovascular Research. 54:601-610
Beneficial effects of n −3 polyunsaturated fatty acids in Ca2+ overload have been attributed to blockade of L-type Ca2+ current ( I Ca-L). However, cardiac contractions may be maintained despite block of I Ca-L. Objective: This study investigates t
It is increasingly evident that polyunsaturated fatty acids (PUFA), which in the past were often believed to be mere components of cellular membranes of neural tissue, are actually major determinants of the functional properties of neural cells and a
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 1361:103-113
We have investigated the mechanistic basis of our recent observation that exposing young mice to an industrial surfactant potentiates the inhibition of fatty-acid β -oxidation that occurs with subsequent virus infection (Murphy et al., Biochim. Biop
Publikováno v:
Molecular and Cellular Biochemistry. 177:257-269
The purpose of this investigation was to determine whether diets supplemented with oils from three different marine sources, all of which contain high proportions of long-chain n-3 polyunsaturated fatty acids (PUFA), result in qualitatively distinct