Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Mary G. McCoy"'
Determining hepatic triglyceride production in mice: comparison of poloxamer 407 with Triton WR-1339
Publikováno v:
Journal of Lipid Research, Vol 46, Iss 9, Pp 2023-2028 (2005)
Triglyceride (TG), a water-insoluble energy-rich lipid, is secreted by the liver as part of very low density lipoproteins (VLDLs) to supply energy to extrahepatic tissues. Overproduction of VLDL is associated with increased risk of cardiovascular hea
Externí odkaz:
https://doaj.org/article/15fbab891c814554b32f7019571ea87d
Autor:
Mary G. McCoy, Gwo-Shing Sun, Dawn Marchadier, Cyrille Maugeais, Jane M. Glick, Daniel J. Rader
Publikováno v:
Journal of Lipid Research, Vol 43, Iss 6, Pp 921-929 (2002)
Endothelial lipase (EL) is a new member of the triglyceride lipase gene family previously reported to have phospholipase activity. Using radiolabeled lipid substrates, we characterized the lipolytic activity of this enzyme in comparison to lipoprotei
Externí odkaz:
https://doaj.org/article/262dadc32c0e42f7b5fe1f40749f4fb5
Autor:
Marjorie Risman, Kevin Trindade, Jeffrey T. Billheimer, Liming Qu, Mary G. McCoy, Amrith Rodrigues, Marina Cuchel, Daniel J. Rader, Anandita P. Agarwala
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 35:1515-1519
Objective— Plasma levels of high-density lipoprotein cholesterol (HDL-C) are strongly inversely associated with coronary artery disease (CAD), and high HDL-C is generally associated with reduced risk of CAD. Extremely high HDL-C with CAD is an unus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c574791b57efd2b381fd1e989e279fe7
https://doi.org/10.1161/atvbaha.115.305504
https://doi.org/10.1161/atvbaha.115.305504
Autor:
Daniel J. Rader, Leonardo Cacciagiú, Laura Schreier, Ana Inés González, Verónica Miksztowicz, Mary G. McCoy, Alicia Elbert, Jeffrey T. Billheimer, Patrick I. Eacho, Gabriela Berg
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 32:3033-3040
Objective— A novel phospholipase assay was used to measure for the first time the behavior of endothelial and hepatic phospholipase activities in postheparin human plasma of hemodialyzed patients and its relationship with atherogenic and antiathero
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a49566945056a0b11e23b62da880e08c
https://doi.org/10.1161/atvbaha.112.300110
https://doi.org/10.1161/atvbaha.112.300110
Autor:
Leland Mayne, Xuemei Zeng, Pradeep Natarajan, Marina Cuchel, Nathan A. Yates, S.W. Englander, James T McParland, Cecilia Vitali, Paolo Zanoni, John S. Millar, Amritha Varshini, Daniel J. Rader, Michael C. Phillips, Mary G. McCoy, David Nguyen, Zhiyuan Sun, Sumeet A. Khetarpal, Sissel Lund-Katz, Sekar Kathiresan
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 36
Humans with loss-of-function (LoF) variants in APOC3 , the gene encoding apolipoprotein C-III (apoC-III), have significantly reduced plasma triglycerides (TG) and protection from coronary disease. These findings suggest that apoC-III may be a viable
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9da376ee5fafe7cf9fcddbef41619cd9
https://doi.org/10.1161/atvb.36.suppl_1.17
https://doi.org/10.1161/atvb.36.suppl_1.17
Autor:
Dawn Marchadier, Uwe J. F. Tietge, Daniel J. Rader, Uli C. Broedl, Mary G. McCoy, Sissel Lund-Katz, William Cain, Cyrille Maugeais, Jane M. Glick
Publikováno v:
Circulation. 108:2121-2126
Background— Factors that regulate the metabolism of HDL and apolipoprotein A-I (apoA-I) are incompletely understood. Overexpression of endothelial lipase (EL) markedly reduces plasma levels of HDL cholesterol and apoA-I in mice, but the mechanisms
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fce48e34ba6b1df2614ac010e97dde05
https://doi.org/10.1161/01.cir.0000092889.24713.dc
https://doi.org/10.1161/01.cir.0000092889.24713.dc
Autor:
Cyrille Maugeais, Daniel J. Rader, Mary G. McCoy, Dawn Marchadier, Gwo-Shing Sun, Jane M. Glick
Publikováno v:
Journal of Lipid Research, Vol 43, Iss 6, Pp 921-929 (2002)
Endothelial lipase (EL) is a new member of the triglyceride lipase gene family previously reported to have phospholipase activity. Using radiolabeled lipid substrates, we characterized the lipolytic activity of this enzyme in comparison to lipoprotei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71036c0785b1e8dab64f6a6aed76d61a
https://doi.org/10.1016/s0022-2275(20)30466-1
https://doi.org/10.1016/s0022-2275(20)30466-1
Autor:
Mary G. McCoy, Verónica Miksztowicz, Laura Schreier, Eduardo Fassio, Daniel J. Rader, Jeffrey T. Billheimer, Gabriela Berg, Diego Martín Lucero
Publikováno v:
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Objective— To assess the phospholipase activity of endothelial (EL) and hepatic lipase (HL) in postheparin plasma of subjects with metabolic syndrome (MS)/obesity and their relationship with atherogenic and antiatherogenic lipoproteins. Additionall
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d15447a22ad2067883471af3e9b6d2b
http://atvb.ahajournals.org/content/34/3/669
http://atvb.ahajournals.org/content/34/3/669
Autor:
Ramprasad Gadi, LeAnne T. Bloedon, Daniel J. Rader, John S. Millar, Danielle Duffy, Ming-Dauh Wang, Megan L. Wolfe, Rajesh Movva, Daniel C. Howey, Mary G. McCoy, Richard L. Dunbar, Cynthia J. Harris, Ilia V. Fuki, Ashish Shah
Publikováno v:
Arteriosclerosis, thrombosis, and vascular biology. 29(1)
Objective— The study of PPAR-α activation on apoA-I production in humans has been limited to fibrates, relatively weak PPAR-α agonists that may have other molecular effects. We sought to determine the effect of a potent and highly specific PPAR-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::176b705581cd1304680094fce1b17ace
https://pubmed.ncbi.nlm.nih.gov/18988892
https://pubmed.ncbi.nlm.nih.gov/18988892
Autor:
Valeska Redon, Donna M. Conlon, Rexford S. Ahima, Batuhan Yenilmez, Stephen L. Sturley, Sean O’Neill, Wen Lin, Miao Wang, William R. Lagor, Rajat Gupta, Daniel J. Rader, Fumin Tong, Kelsey E Jarrett, Mikhaila A Smith, David W Fields, Mary G. McCoy, Arthi Kumaravel, Jeffrey T. Billheimer
Publikováno v:
Nutrition & Diabetes
Background: ACAT-related enzyme 2 required for viability 1 (ARV1) is a putative lipid transporter of the endoplasmic reticulum that is conserved across eukaryotic species. The ARV1 protein contains a conserved N-terminal cytosolic zinc ribbon motif k
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34ca55773e8f6feb9d1a5e0a081b10c3
http://europepmc.org/articles/PMC4631934
http://europepmc.org/articles/PMC4631934