Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Mary G. Leonard"'
Publikováno v:
European Journal of Pharmacology. 789:81-87
Centhaquin has been shown to produce antinociception in the mouse hot plate and tail flick assays through the opioid, the α2A and α2B adrenoceptors. Present study was conducted to determine the effects of centhaquin in a rat model of postoperative
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c31b0085c22a333cdeaa04e11f1fc2b8
https://doi.org/10.1016/j.ejphar.2016.07.016
https://doi.org/10.1016/j.ejphar.2016.07.016
Publikováno v:
Drug Research. 66:189-195
Manipulation of the central endothelin (ET) system via either ETA antagonists or ETB agonists following experimental cerebral ischemia has been shown to be beneficial in previous experimental studies. In order to further explore the involvement of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12a037ea37d2fc1a81529e80d1cf80f0
https://doi.org/10.1055/s-0035-1559779
https://doi.org/10.1055/s-0035-1559779
Publikováno v:
Drug Research. 65:607-613
Endothelin, vascular endothelial growth factor and nerve growth factor play important roles in development of the central nervous system. ET(B) receptors have been shown to promote neurovascular remodeling in the adult ischemic brain through an incre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::257274a108f54f37f1ee6a2ea2f497d6
https://doi.org/10.1055/s-0034-1398688
https://doi.org/10.1055/s-0034-1398688
Autor:
Anil Gulati, Mary G. Leonard
Publikováno v:
Brain Research. 1528:28-41
Endothelin B receptor agonist, IRL-1620, has been shown in previous studies, conducted in our lab, to provide significant neuroprotection at both 24h and 1 week following permanent cerebral ischemia. It is possible that IRL-1620 may be neuroprotectiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::932ec846d1037626dd6c6b8eb43d915d
https://doi.org/10.1016/j.brainres.2013.07.002
https://doi.org/10.1016/j.brainres.2013.07.002
Publikováno v:
Critical Care Medicine. 40:1-328
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d51dec831ef4f8fe6ac67562feb22fd6
https://doi.org/10.1097/01.ccm.0000424410.36936.01
https://doi.org/10.1097/01.ccm.0000424410.36936.01
Publikováno v:
Brain Research. 1464:14-23
We have earlier shown that stimulation of endothelin B receptors by IRL-1620 provides significant neuroprotection at 24 h following cerebral ischemia. However, the effect of IRL-1620 is not known in the subacute phase of cerebral ischemia, where deve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2e8ef273afeadfcb58038fb25007dd1
https://doi.org/10.1016/j.brainres.2012.05.005
https://doi.org/10.1016/j.brainres.2012.05.005
Publikováno v:
Brain Research. 1420:48-58
Endothelin and its receptors have long been considered therapeutic targets in the treatment of ischemic stroke. Recent studies indicate that ET(B) receptors may provide both vasodilatation and neuroprotection. The purpose of this study was to determi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed95fe4eab9107f63f98e271deb2d5b8
https://doi.org/10.1016/j.brainres.2011.08.075
https://doi.org/10.1016/j.brainres.2011.08.075
Publikováno v:
Neuroscience. 301
Alzheimer's disease (AD) is a progressive neurodegenerative disorder characterized by severe cognitive impairment that ultimately leads to death. Endothelin (ET) and its receptors have been considered as therapeutic targets for AD. Recent studies in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::435d4893fe7f9d943e970446091e15f6
https://pubmed.ncbi.nlm.nih.gov/26022359
https://pubmed.ncbi.nlm.nih.gov/26022359
Publikováno v:
Braindevelopment. 37(2)
Background: Endothelin (ET) plays an important role in many physiological functions. It has been demonstrated that endogenous ET-1 concentration in the central nervous system (CNS) changes with age; however the ontogeny of ETA and ETB receptors in th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf3793eefa63c982abfe62d9f1b4c841
https://pubmed.ncbi.nlm.nih.gov/24815227
https://pubmed.ncbi.nlm.nih.gov/24815227
Publikováno v:
Critical Care Medicine. 44:257-257
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4c4ab4decd57e838fd0b8118990e15e7
https://doi.org/10.1097/01.ccm.0000509400.83640.59
https://doi.org/10.1097/01.ccm.0000509400.83640.59