Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Mary G. Goll"'
Autor:
Audrey E. Calvird, Morgan N. Broniec, Katherine L. Duval, Alysha N. Higgs, Vani Arora, Lauren N. Ha, Erik B. Schouten, Annabel R. Crippen, Maura McGrail, Kathrin Laue, Mary G. Goll
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Heterochromatin formation and maintenance is critical for the repression of transcription from repetitive sequences. However, in vivo tools for monitoring heterochromatin mediated repression of repeats in the context of vertebrate development have be
Externí odkaz:
https://doaj.org/article/8bec59b62501424797aced80eb5de7a5
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-10 (2019)
Eukaryotic genomes are segregated into euchromatin and heterochromatin. Here the authors show that heterochromatin establishment during zebrafish embryo development is controlled by zygotic transcription of miR-430 and subsequent degradation of mater
Externí odkaz:
https://doaj.org/article/273ccd9f47f749a8a1d7aa0e38138ee6
Publikováno v:
F1000Research, Vol 9 (2020)
Early animal development is characterized by intense reorganization of the embryonic genome, including large-scale changes in chromatin structure and in the DNA and histone modifications that help shape this structure. Particularly profound shifts in
Externí odkaz:
https://doaj.org/article/3a7cf4f319d34a6d85ecc9f0e0e9a9b9
Autor:
Cheng Li, Yahui Lan, Lianna Schwartz-Orbach, Evgenia Korol, Mamta Tahiliani, Todd Evans, Mary G. Goll
Publikováno v:
Cell Reports, Vol 12, Iss 7, Pp 1133-1143 (2015)
The Tet family of methylcytosine dioxygenases (Tet1, Tet2, and Tet3) convert 5-methylcytosine to 5-hydroxymethylcytosine. To date, functional overlap among Tet family members has not been examined systematically in the context of embryonic developmen
Externí odkaz:
https://doaj.org/article/3bacde917e6a4d8ab5302f8fa1e2ccbf
Publikováno v:
Dev Dyn
Background Cell fate decisions are governed by interactions between sequence-specific transcription factors and a dynamic chromatin landscape. Zebrafish offer a powerful system for probing the mechanisms that drive these cell fate choices, especially
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03b7c90b8d0b526699632025248842ae
https://europepmc.org/articles/PMC8976701/
https://europepmc.org/articles/PMC8976701/
BackgroundCell fate decisions are governed by interactions between sequence-specific transcription factors and a dynamic chromatin landscape. Zebrafish offer a powerful system for probing the mechanisms that drive these cell fate choices, especially
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::10051c56a480a69dd340b3f5ad217902
https://doi.org/10.1101/2021.06.22.447589
https://doi.org/10.1101/2021.06.22.447589
Autor:
Mary G. Goll, Cheng Li, Jasmine Alexandra Fels, Bernard Thisse, Christine Thisse, Jonathan Fillatre, Jean-Daniel Fauny
Publikováno v:
eLife
eLife, Vol 8 (2019)
eLife, Vol 8 (2019)
In many vertebrates, establishment of Left-Right (LR) asymmetry results from the activity of a ciliated organ functioning as the LR Organizer (LRO). While regulation of the formation of this structure by major signaling pathways has been described, t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29b2154fff605bc118871f6afaa376a9
http://europepmc.org/articles/PMC6759317
http://europepmc.org/articles/PMC6759317
Publikováno v:
Trends Genet
Chemical modification of nucleotide bases in DNA provides one mechanism for conveying information in addition to the genetic code. 5-methylcytosine (5mC) represents the most common chemically modified base in eukaryotic genomes. Sometimes referred to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a99a28ecdcdb4e69d19c203951700220
https://pubmed.ncbi.nlm.nih.gov/31399242
https://pubmed.ncbi.nlm.nih.gov/31399242
Publikováno v:
Nature Communications
Nature Communications, Vol 10, Iss 1, Pp 1-10 (2019)
Nature Communications, Vol 10, Iss 1, Pp 1-10 (2019)
The segregation of eukaryotic genomes into euchromatin and heterochromatin represents a fundamental and poorly understood process. Here, we demonstrate that genome-wide establishment of heterochromatin is triggered by the maternal to zygotic transiti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7e439a8d6cb31049263a242fa7da873
http://europepmc.org/articles/PMC6449393
http://europepmc.org/articles/PMC6449393