Zobrazeno 1 - 10
of 122
pro vyhledávání: '"Mary G. Garry"'
Autor:
Satyabrata Das, Vinayak Gupta, Johannes Bjorge, Xiaozhong Shi, Wuming Gong, Mary G. Garry, Daniel J. Garry
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Ets variant 2 (Etv2), a member of the Ets factor family, has an essential role in the formation of endothelial and hematopoietic cell lineages during embryonic development. The functional role of ETS transcription factors is, in part, dependent on th
Externí odkaz:
https://doaj.org/article/ab072e7171734121a591fca05cfc9b52
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
The only curative therapy for many endstage diseases is allograft organ transplantation. Due to the limited supply of donor organs, relatively few patients are recipients of a transplanted organ. Therefore, new strategies are warranted to address thi
Externí odkaz:
https://doaj.org/article/1b29c1d6a6d74d5c846bc0906d9c4178
Publikováno v:
Frontiers in Genetics, Vol 13 (2022)
Focusing on complex extremity trauma and volumetric muscle loss (VML) injuries, this review highlights: 1) the current pathophysiologic limitations of the injury sequela; 2) the gene editing strategy of the pig as a model that provides a novel treatm
Externí odkaz:
https://doaj.org/article/8c9f8b99cee8408497446cba5c557eca
Autor:
Bhairab N. Singh, Wuming Gong, Satyabrata Das, Joshua W. M. Theisen, Javier E. Sierra-Pagan, Demetris Yannopoulos, Erik Skie, Pruthvi Shah, Mary G. Garry, Daniel J. Garry
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-11 (2019)
Abstract Etv2, an Ets-transcription factor, governs the specification of the earliest hemato-endothelial progenitors during embryogenesis. While the transcriptional networks during hemato-endothelial development have been well described, the mechanis
Externí odkaz:
https://doaj.org/article/eda0d5c70def493b993477499d9dd848
Autor:
Bhairab N. Singh, Naoko Koyano-Nakagawa, Wuming Gong, Ivan P. Moskowitz, Cyprian V. Weaver, Elizabeth Braunlin, Satyabrata Das, Jop H. van Berlo, Mary G. Garry, Daniel J. Garry
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-18 (2018)
Due to the limited proliferation capacity of adult mammalian cardiomyocytes, the human heart has negligible regenerative capacity after injury. Here the authors show that a Hedgehog-Gli1-Mycn signaling cascade regulates cardiomyocyte proliferation an
Externí odkaz:
https://doaj.org/article/e834b139d7d24de2a7e908969edba69b
Autor:
Bhairab N. Singh, Yasuhiko Kawakami, Ryutaro Akiyama, Tara L. Rasmussen, Mary G. Garry, Wuming Gong, Satyabrata Das, Xiaozhong Shi, Naoko Koyano-Nakagawa, Daniel J. Garry
Publikováno v:
Cell Reports, Vol 13, Iss 5, Pp 915-923 (2015)
MicroRNAs (miRNAs) are known to regulate critical developmental stages during embryogenesis. Here, we defined an Etv2-miR-130a cascade that regulates mesodermal specification and determination. Ablation of Dicer in the Etv2-expressing precursors resu
Externí odkaz:
https://doaj.org/article/bfe896d61df64337aabf7195e993141c
Publikováno v:
Journal of Molecular and Cellular Cardiology. 172:109-119
End stage heart failure is a terminal disease, and the only curative therapy is orthotopic heart transplantation. Due to limited organ availability, alternative strategies have received intense interest for treatment of patients with advanced heart f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e1f3b9145c90c4f4ee2a8ce93a6322f
https://doi.org/10.1016/j.yjmcc.2022.07.013
https://doi.org/10.1016/j.yjmcc.2022.07.013
Autor:
Javier E Sierra-Pagan, Nikita Dsouza, Satyabrata Das, Thijs A Larson, Jacob R Sorensen, Xiao Ma, Patricia Stan, Erik J Wanberg, Xiaozhong Shi, Mary G Garry, Wuming Gong, Daniel J Garry
Publikováno v:
Cardiovascular Research.
Aims Congenital heart disease (CHD) is the most common genetic birth defect, which has considerable morbidity and mortality. We focused on deciphering key regulators that govern cardiac progenitors and cardiogenesis. FOXK1 is a forkhead/winged helix
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cbc742cb027890a56fe371c3a9ed36a6
https://doi.org/10.1093/cvr/cvad054
https://doi.org/10.1093/cvr/cvad054
Autor:
Wuming Gong, Satyabrata Das, Javier E. Sierra-Pagan, Erik Skie, Nikita Dsouza, Thijs A. Larson, Mary G. Garry, Edgar Luzete-Monteiro, Kenneth S. Zaret, Daniel J. Garry
Publikováno v:
Nature Cell Biology. 24:672-684
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a11414f3e7ee9f27925364c930a7ce67
https://doi.org/10.1038/s41556-022-00901-3
https://doi.org/10.1038/s41556-022-00901-3
Publikováno v:
XenotransplantationREFERENCES.
Cardiovascular disease is common and has a high mortality. Due to the limited number of organs available for orthotopic heart transplantation, alternative therapies have received intense interest. In this commentary we contrast xenotransplantation an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5352c833e04ad08dc0c727e6235895f7
https://pubmed.ncbi.nlm.nih.gov/36367201
https://pubmed.ncbi.nlm.nih.gov/36367201