Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Mary Esmeralda Fuentes"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract Pancreatic neuroendocrine tumors (PanNETs) are a heterogeneous group of tumors that exhibit an unpredictable and broad spectrum of clinical presentations and biological aggressiveness. Surgical resection is still the only curative therapeuti
Externí odkaz:
https://doaj.org/article/65dcf10b92a145568ca7887dc173e110
Autor:
Marcello Caporicci, Pawel K. Mazur, Zhentian Wang, Julien Sage, Mary Esmeralda Fuentes, Joshua E. Elias, Matthew J. Meiners, Sarah A. Howard, Lichao Zhang, Michael C. Bassik, Or Gozani, Ze Yang, Tie-Mei Li, Shane Lofgren, Michael P. Kim, Anirban Maitra, Natasha M. Flores, Simone Hausmann, Huamin Wang, Ruitu Lyu, Michael-Christopher Keogh, Marcus A. Cheek
Publikováno v:
Cancer Cell
Summary Molecular mechanisms underlying adaptive targeted therapy resistance in pancreatic ductal adenocarcinoma (PDAC) are poorly understood. Here, we identify SETD5 as a major driver of PDAC resistance to MEK1/2 inhibition (MEKi). SETD5 is induced
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b692d6b807b4ea827aa62dbcb8e7a095
https://europepmc.org/articles/PMC8187079/
https://europepmc.org/articles/PMC8187079/
Autor:
Shuo Liu, Nicholas D. Nguyen, John A. Porco, Laura Hulea, Marcello Caporicci, Jiuwei Lu, Jikui Song, Ami Li, Or Gozani, Shane Lofgren, Simone Hausmann, Michael Paul Kim, Pawel K. Mazur, Anirban Maitra, Capucine Van Rechem, Michael C. Bassik, Huamin Wang, Kristofferson Tandoc, Renjitha Pillai, Ivan Topisirovic, Mary Esmeralda Fuentes, Ignacio I. Wistuba, Joshua E. Elias, Joel William Francis, Scott M. Carlson
Publikováno v:
Cell, vol 176, iss 3
We thank Pal Falnes, Jerry Pelletier, and Julien Sage for helpful discussion, Lauren Brown and William Devine for SDS-1-021, and members of the Gozani and Mazur laboratories for critical reading of the manuscript. This work was supported in part by g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b44e9140a251a85ef0efbc768b62fe5
https://escholarship.org/uc/item/0fn1714s
https://escholarship.org/uc/item/0fn1714s