Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Mary Ellen Molloy"'
Publikováno v:
Molecular Cancer, Vol 16, Iss 1, Pp 1-1 (2017)
Externí odkaz:
https://doaj.org/article/e9aaeaf5e6064e07b741d6e9dfa8f604
Autor:
Debra A. Tonetti, Gregory R.J. Thatcher, V. Craig Jordan, Philipp Y. Maximov, Huiping Zhao, Hitisha Patel, Rui Xiong, Bradley T. Michalsen, Teshome Gherezghiher, Bethany E. Perez White, Mary Ellen Molloy
Supplementary Figure 2: (A) Reconstructed ion chromatogram for the MRM transition m/z 241 to 208 of standard BTC (100ng/mL); (B) Reconstructed ion chromatogram for the MRM transition m/z 709 to 171 of standard DansylBTC (100ng/ml).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::553da67c96bd09e470eeffcb4947f81c
https://doi.org/10.1158/1535-7163.22501807.v1
https://doi.org/10.1158/1535-7163.22501807.v1
Autor:
Debra A. Tonetti, Gregory R.J. Thatcher, V. Craig Jordan, Philipp Y. Maximov, Huiping Zhao, Hitisha Patel, Rui Xiong, Bradley T. Michalsen, Teshome Gherezghiher, Bethany E. Perez White, Mary Ellen Molloy
Supplementary Figure 6: Plasma concentration-time profile of BTC following the administration of a single oral dose of 10 mg/Kg BTC to mice. Each data point represents the mean value {plus minus} SD (n = 3).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e44eaca976fbd326be9d8b22ce1549e1
https://doi.org/10.1158/1535-7163.22501795.v1
https://doi.org/10.1158/1535-7163.22501795.v1
Autor:
Debra A. Tonetti, Gregory R.J. Thatcher, V. Craig Jordan, Philipp Y. Maximov, Huiping Zhao, Hitisha Patel, Rui Xiong, Bradley T. Michalsen, Teshome Gherezghiher, Bethany E. Perez White, Mary Ellen Molloy
Supplementary Figure 3: Reagents and conditions: (a) N-Bromoacetamide, DCM, EtOH, rt; (b) BBr3, dry DCM, 0sup>; (c) Dansyl chloride, TEA, DCM, 60 sup>C.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ee627368b0944458f58b75004103c50
https://doi.org/10.1158/1535-7163.22501804.v1
https://doi.org/10.1158/1535-7163.22501804.v1
Autor:
Debra A. Tonetti, Gregory R.J. Thatcher, V. Craig Jordan, Philipp Y. Maximov, Huiping Zhao, Hitisha Patel, Rui Xiong, Bradley T. Michalsen, Teshome Gherezghiher, Bethany E. Perez White, Mary Ellen Molloy
Supplementary Figure 4: The calibration standards were prepared by spiking working solution and IS (20ng/mL) into blank mouse plasma, giving final BTC concentrations of 5,10, 20, 30, 40, 50, and 100 ng/mL.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6134a2720a19720ca0dc869aea26b3f5
https://doi.org/10.1158/1535-7163.22501801.v1
https://doi.org/10.1158/1535-7163.22501801.v1
Autor:
Debra A. Tonetti, Gregory R.J. Thatcher, V. Craig Jordan, Philipp Y. Maximov, Huiping Zhao, Hitisha Patel, Rui Xiong, Bradley T. Michalsen, Teshome Gherezghiher, Bethany E. Perez White, Mary Ellen Molloy
Supplementary Figure 1: Western blot showing ERalpha expression in T47D:A18/neo, T47D:A18/PKCalpha, T47D:A18, T47D:A18-TAM1, MCF-7:WS8 and MCF-7 5C cell lines.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04fb5918be1e022be3c928f89ea7f82a
https://doi.org/10.1158/1535-7163.22501810
https://doi.org/10.1158/1535-7163.22501810
Autor:
Holger Wesche, Che-Leung Law, Patrick A. Baeuerle, Timothy Z. Yu, Laurie Tatalick, Kenneth Sexton, Purbasa Patnaik, Kathryn L. Strobel, Susan D. Jones, Adrie Jones, Vaishnavi Ganti, Wade H. Aaron, Bryan D. Lemon, Richard J. Austin, Mary Ellen Molloy
Purpose:Mesothelin (MSLN) is a glycophosphatidylinositol-linked tumor antigen overexpressed in a variety of malignancies, including ovarian, pancreatic, lung, and triple-negative breast cancer. Early signs of clinical efficacy with MSLN-targeting age
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb32ac1e74423fb577ba10f3003d4017
https://doi.org/10.1158/1078-0432.c.6530192.v1
https://doi.org/10.1158/1078-0432.c.6530192.v1
Autor:
Holger Wesche, Che-Leung Law, Patrick A. Baeuerle, Timothy Z. Yu, Laurie Tatalick, Kenneth Sexton, Purbasa Patnaik, Kathryn L. Strobel, Susan D. Jones, Adrie Jones, Vaishnavi Ganti, Wade H. Aaron, Bryan D. Lemon, Richard J. Austin, Mary Ellen Molloy
Supplementary data
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a58f328683170de211f22dc75c58662
https://doi.org/10.1158/1078-0432.22479320
https://doi.org/10.1158/1078-0432.22479320
Autor:
Laura B. Valenzuela, Chi-Heng Wu, Wade Aaron, Raphalea R. Banzon, Mabel Bush, S. Jack Lin, Sony S. Rocha, Subramanian Thothathri, Holger Wesche, Mary Ellen Molloy, Banmeet S. Anand
Publikováno v:
Cancer Research. 83:5070-5070
TriTAC® is a T cell engager platform comprised of three binding domains: a target binder for tumor cell engagement, an albumin binder for half-life extension, and a CD3 binder for T cell engagement. HPN328 is a Delta-like ligand 3 (DLL3)-targeting T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0105608c031459aafbf4ca3c05c93279
https://doi.org/10.1158/1538-7445.am2023-5070
https://doi.org/10.1158/1538-7445.am2023-5070
Autor:
Che-Leung Law, Holger Wesche, Timothy Yu, Richard J. Austin, Vaishnavi Ganti, Mary Ellen Molloy, Kathryn L. Strobel, Susan D. Jones, Purbasa Patnaik, Laurie Tatalick, A. Jones, Kenneth Sexton, Patrick A. Baeuerle, Wade Aaron, Lemon Bryan D
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 27(5)
Purpose: Mesothelin (MSLN) is a glycophosphatidylinositol-linked tumor antigen overexpressed in a variety of malignancies, including ovarian, pancreatic, lung, and triple-negative breast cancer. Early signs of clinical efficacy with MSLN-targeting ag
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2a05654dbacd41d8f81d7ec5c1ac869
https://pubmed.ncbi.nlm.nih.gov/33262134
https://pubmed.ncbi.nlm.nih.gov/33262134