Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Mary Ellen Davies"'
Autor:
Donald J. Graham, Steven W. Ludmerer, David B. Olsen, Nanyan Rena Zhang, Kenneth A. Koeplinger, Malcolm MacCoss, Daria J. Hazuda, Mary-Ellen Davies, Larry Handt, Steven S. Carroll
Publikováno v:
Antimicrobial Agents and Chemotherapy. 53:926-934
Hepatitis C virus (HCV) infects an estimated 170 million individuals worldwide and is associated with an increased incidence of liver fibrosis, cirrhosis, and hepatocellular carcinoma. Currently approved therapies to treat HCV infection consist of co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cc7fc654defa660808a6f908c677c21
https://doi.org/10.1128/aac.01032-08
https://doi.org/10.1128/aac.01032-08
Autor:
Lynda G. Tussey, Kara J. Sykes, Adam C. Finnefrock, Andrew J. Bett, David H. O’Connor, Adrian B. McDermott, Gwendolyn J. Heidecker, Lingyi Huang, Keith A. Wilson, Xiaoping Liang, Virginia I. Ausensi, Usha Sadasivan-Nair, John W. Shiver, Mary-Ellen Davies, Helen C. Perry, Kara Punt, Daniel C. Freed, Zhiqiang Zhang, Timothy W. Tobery, Arthur Fridman, Minchun Chen, Ansu Bagchi, Margaret Bachinsky, William A. Schleif, David I. Watkins, Aimin Tang, Tong-Ming Fu, Emilio A. Emini, Fubao Wang, Anthony Carella, Danilo R. Casimiro
Publikováno v:
Journal of Virology. 79:15547-15555
The prophylactic efficacy of DNA and replication-incompetent adenovirus serotype 5 (Ad5) vaccine vectors expressing simian immunodeficiency virus (SIV) Gag was examined in rhesus macaques using an SIVmac239 challenge. Cohorts of either Mamu-A*01(+) o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::871d32543552dcd6aef4d205a168e223
https://doi.org/10.1128/jvi.79.24.15547-15555.2005
https://doi.org/10.1128/jvi.79.24.15547-15555.2005
Autor:
Andrew J. Bett, Romnie Long, Minchun Chen, Aimin Tang, Michael Chastain, Emilio A. Emini, Danilo R. Casimiro, John W. Shiver, Tong-Ming Fu, Mary-Ellen Davies, Sanjay Gurunathan, Troy McKelvey, Jim Tartaglia, Keith A. Wilson
Publikováno v:
Journal of Virology. 78:11434-11438
We compared the human immunodeficiency virus type 1 (HIV-1)-specific cellular immune responses elicited in nonhuman primates by HIV-1 gag -expressing replication-defective adenovirus serotype 5 (Ad5) or poxvirus vectors, used either alone or in combi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c56e7fdc4278d021c7577747bdef1804
https://doi.org/10.1128/jvi.78.20.11434-11438.2004
https://doi.org/10.1128/jvi.78.20.11434-11438.2004
Autor:
Paul M. Keller, John W. Shiver, Victor M. Garsky, Mary-Ellen Davies, Roxana Ionescu, Jiang Fan, Jon H. Condra, Helen C. Perry, Melanie Horton, Li Shi, Jason J. Z. Liao, Gwen J Heidecker, Xiaoping Liang, Michael Chastain, Emilio A. Emini, Yvette Rippeon, Joseph G. Joyce, Tong-Ming Fu, Michael P. Citron, Craig T. Przysiecki
Publikováno v:
Vaccine. 22:2993-3003
A universal influenza virus vaccine that does not require frequent updates and/or annual immunizations will offer significant advantages over current seasonal flu vaccines. The highly conserved influenza virus A M2 membrane protein has been previousl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1238143103e6c5b2fff7b8094376b954
https://doi.org/10.1016/j.vaccine.2004.02.021
https://doi.org/10.1016/j.vaccine.2004.02.021
Autor:
Xiaoping Liang, Anthony Carella, John W. Shiver, Brett Connolly, Charles Tan, Danilo R. Casimiro, Emilio A. Emini, Hilton J. Klein, Larry Handt, Aimin Tang, Minchun Chen, William A. Schleif, Michael McElhaugh, Tong-Ming Fu, Mary-Ellen Davies, Susan Hill, Keith A. Wilson, Zhiqiang Zhang
Publikováno v:
Virology. 320(1):75-84
Set-point viral load is positively correlated with the extent of initial viral replication in pathogenic simian-human immunodeficiency virus (SHIV) infection. To elucidate the mechanisms underlying the correlation, we conducted a systematic investiga
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7d8fa5b9c5cbfd81f68dff907b5b75e
Autor:
Jose M. Aste-Amezaga, Lynne Isopi, Ling Chen, David B. Volkin, Liming Guan, Aimin Tang, Tong-Ming Fu, Virginia Harris, John W. Shiver, Emilio A. Emini, Danilo R. Casimiro, Lingyi Huang, Robert D. Troutman, Mary-Ellen Davies, Karen Rice, Keith A. Wilson, Daniel C. Freed, Henryk Mach, Romnie Long, Krishna K. Murthy, Denise K. Nawrocki, William Hurni, Robert K. Evans
Publikováno v:
Journal of Virology. 77:7663-7668
The cellular immunogenicity of formulated plasmid DNA and replication-defective human adenovirus serotype 5 (Ad5) vaccine vectors expressing a codon-optimized human immunodeficiency virus type 1 gag gene was examined in baboons. The Ad5 vaccine was c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74b42569a51467aa5ca4bec7c484bfaa
https://doi.org/10.1128/jvi.77.13.7663-7668.2003
https://doi.org/10.1128/jvi.77.13.7663-7668.2003
Autor:
Odalys Gonzalez Paz, Stefania Lamartina, Hermann Bujard, Danilo R. Casimiro, Gennaro Ciliberto, John W. Shiver, Guiseppe Roscilli, Mary Ellen Davies, Stefano Colloca, Cira Daniela Rinaudo, Adam J. Simon, Luisa Silvi, Carlo Toniatti, Elena Fattori, Riccardo Cortese, Immacolata Zampaglione, Ralph Laufer
Publikováno v:
Molecular Therapy. 7:271-280
The tetracycline (Tc)-dependent system in its "on" version (rtTA system) displays a baseline activity in the uninduced state, severely limiting its potential applicability in human gene therapy. So far, two different strategies to circumvent this lim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b87867678834eeb73cfd76fc874220fb
https://doi.org/10.1016/s1525-0016(02)00051-5
https://doi.org/10.1016/s1525-0016(02)00051-5
Autor:
Gwendolyn J. Heidecker, Helen C. Perry, Romnie Long, Minchun Chen, Michael Chastain, John W. Shiver, Natasha V. Persaud, Adam J. Simon, Jeffrey G. Smith, Diane V. Havlir, Tong-Ming Fu, Danilo R. Casimiro, Aimin Tang, Emilio A. Emini, Mary-Ellen Davies, Daniel C. Freed, Sheri Dubey, Douglas D. Richman
Publikováno v:
Journal of Virology. 76:185-194
A synthetic gene consisting of the reverse transcriptase (RT) and integrase (IN) domains of human immunodeficiency virus type 1 (HIV-1) pol was constructed using codons most frequently used in humans. The humanized pol gave dramatically improved leve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1b1de880f673a919fc738474eec65ef
https://doi.org/10.1128/jvi.76.1.185-194.2002
https://doi.org/10.1128/jvi.76.1.185-194.2002
Autor:
Terry B. Strom, Gwendolyn J. Heidecker, John W. Shiver, Christine E. Nickerson, Helen C. Perry, Sampa Santra, Hong Xie, Michelle A. Lifton, Xin Xiao Zheng, Carroll L. Crabbs, Dan H. Barouch, Georgia R. Krivulka, Carol I. Lord, Tavis D. Steenbeke, Julie D. Frost, David C. Montefiori, Marcelo J. Kuroda, Mary-Ellen Davies, Mark G. Lewis, Abie Craiu, Jörn E. Schmitz, Norman L. Letvin
Publikováno v:
Proceedings of the National Academy of Sciences. 97:4192-4197
The potential utility of plasmid DNA as an HIV-1 vaccination modality currently is an area of active investigation. However, recent studies have raised doubts as to whether plasmid DNA alone will elicit immune responses of sufficient magnitude to pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d37aeccf743bbcf9c7bb22ec45819f7
https://doi.org/10.1073/pnas.050417697
https://doi.org/10.1073/pnas.050417697