Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Mary E.P. Goad"'
Autor:
Man Shiow Jiang, Ronald L. Stotish, Lori A. Reed, En Li, Se-Jin Lee, Monique V. Davies, Li Fang Liang, Mary E.P. Goad, Neil M. Wolfman, Suzanne Sebald, Stefan Girgenrath, Edwin Quattlebaum, Kathy Tomkinson, Jill F. Wright, Gregory Ehrmantraut, James Holmstrom, Christopher M. Barker, Barry Gertz, Betty Trowell, Martin M. Matzuk
Publikováno v:
Proceedings of the National Academy of Sciences. 102:18117-18122
Myostatin is a secreted protein that normally functions as a negative regulator of muscle growth. Agents capable of blocking the myostatin signaling pathway could have important applications for treating human muscle degenerative diseases as well as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8e7e2b74b251d8a619cbdb1e362cdd2
https://doi.org/10.1073/pnas.0505996102
https://doi.org/10.1073/pnas.0505996102
Autor:
Anthony Wong, Richard A. Flavell, Mary E.P. Goad, Claire R. Weston, J. Perry Hall, Roger J. Davis
Publikováno v:
Proceedings of the National Academy of Sciences. 101:14114-14119
The c-Jun NH 2 -terminal kinase (JNK) group of mitogen-activated protein kinases is activated in response to a wide array of cellular stresses and proinflammatory cytokines. Roles for JNK in the developing nervous system and T-cell-mediated immunity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d260a11e45c10b520c7ab7ceecd9306
https://doi.org/10.1073/pnas.0406061101
https://doi.org/10.1073/pnas.0406061101
Autor:
J. Perry Hall, Richard A. Flavell, Roger J. Davis, Anthony C. Wong, Claire R. Weston, Mary E.P. Goad
Publikováno v:
Genes & Development. 17:1271-1280
The c-Jun NH2-terminal kinase (JNK) group of mitogen-activated protein kinases is stimulated in response to a wide array of cellular stresses and proinflammatory cytokines. Mice lacking individual members of theJnkfamily (Jnk1,Jnk2, andJnk3) are viab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20b4ad8620adde41f1f4cb49af0cc6f2
https://doi.org/10.1101/gad.1087303
https://doi.org/10.1101/gad.1087303
Autor:
Allen W. Cheever, Debra D. Donaldson, Michael J. Grusby, Mary Collins, Monica G. Chiaramonte, Mary E.P. Goad, Bruce A. Jacobson, Matthew J. Whitters, Thomas A. Wynn, Margaret M. Mentink-Kane, Anthony Wong
Publikováno v:
The Journal of Experimental Medicine
Highly polarized type 2 cytokine responses can be harmful and even lethal to the host if they are too vigorous or persist too long. Therefore, it is important to elucidate the mechanisms that down-regulate these reactions. Interleukin (IL)-13 has eme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa03686b04d16769c060cddcdde742cb
https://doi.org/10.1084/jem.20020903
https://doi.org/10.1084/jem.20020903
Autor:
Stanley Wolf, Lori L. Hayes, Mary E.P. Goad, Jamie Erickson, Kyriaki Dunussi-Joannopoulos, Huanfang Zhou, Ed Clark, Stuart Friedrich, Anthony Wong, Manuel Sequeira, Ronald C. Li
Publikováno v:
Clinical Immunology. 101:303-314
The efficacy of chemotherapy for cancer is often limited by toxicity. Immune approaches to cancer immunotherapy, while promising for specificity and long-term protection, have not typically proven potent enough to generate significant therapeutic res
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48b7618cd44dc9a50257985ee1af1c20
https://doi.org/10.1006/clim.2001.5123
https://doi.org/10.1006/clim.2001.5123
Autor:
Stephen P. Lee, Mary E.P. Goad, Steven A. Barker, David G. Baker, H. Wayne Taylor, Jay C. Means
Publikováno v:
Toxicologic Pathology. 29:328-332
Humans may be exposed to 2-aminoanthracen e (2-AA), a substituted polycyclic aromatic hydrocarbon, and a recognized mutagen and carcinogen, through oral and respiratory routes from contact with a variety of environmental sources. For the present stud
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8f5c903d222f891fb962b62099047f0
https://doi.org/10.1080/019262301316905282
https://doi.org/10.1080/019262301316905282
Publikováno v:
Journal of Applied Toxicology. 19:83-91
An isolated rat lung model was established and validated for use in pulmonary metabolism studies. During the establishment phase of the study, several problems were encountered and overcome in order to maintain the lungs in physiological condition. I
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6a63c8c8836a1fcf58a9cb5d66e82e32
https://doi.org/10.1002/(sici)1099-1263(199903/04)19:2<83::aid-jat541>3.0.co
https://doi.org/10.1002/(sici)1099-1263(199903/04)19:2<83::aid-jat541>3.0.co
Autor:
Dale L. Goad, Mary E.P. Goad
The number, variety, and complexity of medical devices have increased over the years. Devices may be composed of a single biomaterial or a composite of two or more materials. Non-clinical assessment involves toxicity testing of individual components
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7bd8387cae365fe591a7711d980e9151
https://doi.org/10.1016/b978-0-12-415759-0.00026-1
https://doi.org/10.1016/b978-0-12-415759-0.00026-1
Autor:
Mary E.P. Goad, Ann V. Als, Patricia C. Come, Juan R. Serur, Judith K. Gwathmey, Shoichiro Nakao, Walter H. Abelmann
Publikováno v:
Journal of the American College of Cardiology. 19(4):864-869
Twenty-six young pigs were infected with encephalomyocarditis virus, observed clinically, studied at intervals by noninvasive and invasive methods to assess cardiac function and eventually examined pathologically.All infected animals appeared ill, us
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fb01a093a23487b51bcaf47a47138da
Autor:
Dale L. Goad, Mary E.P. Goad
Publikováno v:
Handbook of Toxicologic Pathology (Second Edition)
This chapter discusses about biomedical devices and biomaterials. The purpose of this chapter is to describe and define the major biomaterials used as biomedical implants or biomedical devices in humans and animals; and to discuss methods of assessin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f27ed106e282720cca68f7456cae6947
https://doi.org/10.1016/b978-012330215-1/50020-x
https://doi.org/10.1016/b978-012330215-1/50020-x