Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Mary E. Rothstein"'
Autor:
Autumn L. Gaither-Davis, Jill M. Siegfried, K. Jin Kim, Naftali Kaminski, Stephanie R. Land, Diana Lenzner, Phouthone Keohavong, Mary E. Rothstein, Laura P. Stabile
Publikováno v:
Cancers, Vol 2, Iss 4, Pp 2153-2170 (2010)
EGFR and c-Met are both overexpressed in lung cancer and initiate similar downstream signaling, which may be redundant. To determine how frequently ligands that initiate signaling of both pathways are found in lung cancer, we analyzed serum for hepat
Externí odkaz:
https://doaj.org/article/b04d1180c24846319e50dc55b8d1ab5b
Autor:
Jill M. Siegfried, Jennifer R. Grandis, Robert L. Ferris, Sarah Morgan, Kelly M. Quesnelle, Shinsuke Suzuki, Raja R. Seethala, Edwina C. Lerner, Christopher T. Gubish, Sufi M. Thomas, Mary E. Rothstein, Ann Marie Egloff, Laura P. Stabile, Lynn M. Knowles
Supplementary Data from HGF and c-Met Participate in Paracrine Tumorigenic Pathways in Head and Neck Squamous Cell Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a39a53284e69761465d73a92910eaae
https://doi.org/10.1158/1078-0432.22440661.v1
https://doi.org/10.1158/1078-0432.22440661.v1
Autor:
Jill M. Siegfried, Jennifer R. Grandis, Robert L. Ferris, Sarah Morgan, Kelly M. Quesnelle, Shinsuke Suzuki, Raja R. Seethala, Edwina C. Lerner, Christopher T. Gubish, Sufi M. Thomas, Mary E. Rothstein, Ann Marie Egloff, Laura P. Stabile, Lynn M. Knowles
Purpose: We determined hepatocyte growth factor (HGF) and c-Met expression and signaling in human head and neck squamous cell carcinoma (HNSCC) cells and primary tissues and tested the ability of c-Met tyrosine kinase inhibitors (TKI) to block HGF-in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::581b62649effa2aa919a7791bbf8619a
https://doi.org/10.1158/1078-0432.c.6517960.v1
https://doi.org/10.1158/1078-0432.c.6517960.v1
Autor:
Jill M. Siegfried, Austin M. Dulak, K. Jin Kim, The Minh Luong, Sanja Dacic, Stephanie R. Land, Jinling Yin, Jide Jin, Phouthone Keohavong, Mary E. Rothstein, Laura P. Stabile
The hepatocyte growth factor (HGF)/c-Met signaling pathway is involved in lung tumor growth and progression, and agents that target this pathway have clinical potential for lung cancer treatment. L2G7, a single potent anti-human HGF neutralizing mono
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1786ac6c6ef706348c753f3ad88b6f20
https://doi.org/10.1158/1535-7163.c.6531021.v1
https://doi.org/10.1158/1535-7163.c.6531021.v1
Autor:
Jill M. Siegfried, Austin M. Dulak, K. Jin Kim, The Minh Luong, Sanja Dacic, Stephanie R. Land, Jinling Yin, Jide Jin, Phouthone Keohavong, Mary E. Rothstein, Laura P. Stabile
Supplementary Fig. S1 from Therapeutic targeting of human hepatocyte growth factor with a single neutralizing monoclonal antibody reduces lung tumorigenesis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ed8a521336690c29916e7c40536c7f5
https://doi.org/10.1158/1535-7163.22482858.v1
https://doi.org/10.1158/1535-7163.22482858.v1
Autor:
Jill M. Siegfried, Cassandra Henry, Christopher T. Gubish, Laura P. Stabile, Mary E. Rothstein
Publikováno v:
Journal of Thoracic Oncology. 7:485-495
IntroductionEstrogen is known to promote proliferation and to activate the epidermal growth factor receptor (EGFR) in non-small cell lung cancer (NSCLC). Vascular endothelial growth factor (VEGF) is a known estrogen responsive gene in breast cancer.
Autor:
Jill M. Siegfried, Laura P. Stabile, Phouthone Keohavong, K. Jin Kim, Stephanie R. Land, Mary E. Rothstein, Naftali Kaminski, Autumn Gaither-Davis, Diana Lenzner
Publikováno v:
Cancers
Cancers, Vol 2, Iss 4, Pp 2153-2170 (2010)
Cancers; Volume 2; Issue 4; Pages: 2153-2170
Cancers, Vol 2, Iss 4, Pp 2153-2170 (2010)
Cancers; Volume 2; Issue 4; Pages: 2153-2170
EGFR and c-Met are both overexpressed in lung cancer and initiate similar downstream signaling, which may be redundant. To determine how frequently ligands that initiate signaling of both pathways are found in lung cancer, we analyzed serum for hepat
Autor:
Mary E. Rothstein, Mark Nichols, Laura P. Stabile, Chris T. Gubish, Yongli Shuai, Beatriz Kanterewicz, Pamela A. Hershberger, Jill M. Siegfried, Stephanie R. Land
Publikováno v:
The Journal of Steroid Biochemistry and Molecular Biology. 116:102-109
In non-small cell lung cancer (NSCLC) cells, 17beta-estradiol increases transcription, activates MAPK, and stimulates proliferation. We hypothesize that estrogen receptor beta (ERbeta) mediates these responses because it, but not ERalpha, is detected
Autor:
Jill M. Siegfried, Christopher T. Gubish, Sarah Morgan, Laura P. Stabile, Ann Marie Egloff, Robert L. Ferris, Sufi M. Thomas, Kelly M. Quesnelle, Edwina C. Lerner, Mary E. Rothstein, Jennifer R. Grandis, Lynn M. Knowles, Shinsuke Suzuki, Raja R. Seethala
Publikováno v:
Clinical Cancer Research. 15:3740-3750
Purpose: We determined hepatocyte growth factor (HGF) and c-Met expression and signaling in human head and neck squamous cell carcinoma (HNSCC) cells and primary tissues and tested the ability of c-Met tyrosine kinase inhibitors (TKI) to block HGF-in
Autor:
Christopher T. Gubish, Jill M. Siegfried, Laura P. Stabile, Mary E. Rothstein, Pierre E. Queiroz de Oliveira
Publikováno v:
Molecular Pharmacology. 72:769-779
Many studies have suggested a role for the hepatocyte growth factor (HGF)/c-Met pathway in tumorigenesis. Some actions of HGF are believed to be mediated by cyclooxygenase-2 (COX-2), resulting in the production of prostaglandin E2 (PGE(2)). We examin