Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Mary E. Neilly"'
Publikováno v:
Leukemialymphoma. 5(5-6)
We have identified a family in which three members developed B-cell lymphoproliferative disorders within a nine month period. The 33 year old proband and his mother have hairy cell leukemia, and his 37 year old brother developed a large cell lymphoma
Autor:
Yanming Zhang, Elizabeth M. Davis, Janet D. Rowley, Brigitte Schlegelberger, Heidrun D. Gerr, Michele L. Nassin, Mary E. Neilly, Nimanthi Jayathilaka
Publikováno v:
Cancer Genetics and Cytogenetics. 176:131-136
The PRDX4 gene located at Xp22 codes for a member of the peroxiredoxin gene family. Genes within this family exhibit thioredoxin-dependent peroxidase activity and have been implicated in cellular functioning, including proliferation and differentiati
Autor:
Rui Su, Pumin Zhang, Xi Jiang, Zhixiang Zuo, Sandeep Gurbuxani, Lichuan Tang, Huilin Huang, Xi Qin, Hengyou Weng, Shenglai Li, Chenying Li, Ping Chen, Chuan He, Mary E. Neilly, Hao Huang, Xiao Wang, Zejuan Li, Richard A. Larson, Jie Jin, Jennifer Strong, Gia-Ming Hong, Xiaocheng Weng, Yungui Wang, Jianjun Chen, Yuanyuan Li, Chao Hu, Stephen Arnovitz
Publikováno v:
Blood. 128:2706-2706
Introduction N 6-methyladenosine (m6A) is the most abundant internal modification in messenger RNA (mRNA) mainly occurring at consensus motif of G[G>A]m6AC[U>A>C]. Despite the functional importance of m6A modification in various fundamental bioproces
Autor:
Xi Jiang, Hao Huang, Hengyou Weng, Yuanyuan Li, Jinhua Wang, Zejuan Li, Mary E. Neilly, Shenglai Li, Stephen Arnovitz, Ping Chen, Yungui Wang, Jianjun Chen
Publikováno v:
Blood. 124:1011-1011
Approximately 10% of human acute leukemias are involved in chromosomal translocations between the mixed lineage leukemia (MLL) gene and over 50 partner genes. MLL-rearranged leukemias occur preferentially in infant and young children and are often as
Autor:
Zejuan Li, Jiwang Zhang, Tobias Herold, Zhixiang Zuo, Hengyou Weng, Michelle M. Le Beau, Mary E. Neilly, Ping Chen, Justin Salat, Bryan Ulrich, Yuanyuan Li, Yang Yang, Sandeep Gurbuxani, Hao Huang, Stefan K. Bohlander, Richard A. Larson, Chao Hu, Xi Jiang, Stephen Arnovitz, Shenglai Li, Jason Bugno, Jie Jin, Yungui Wang, Seungpyo Hong, Jianjun Chen
Publikováno v:
Blood. 124:886-886
Acute myeloid leukemia (AML) is one of the most common and fatal forms of hematopoietic malignancies with diverse chromosomal and molecular abnormalities. The majority of AML patients do not survive more than 5 years. Advanced genomic studies reveal
Autor:
Shantel, Corbin, Mary E, Neilly, Rafael, Espinosa, Elizabeth M, Davis, Timothy W, McKeithan, Michelle M, Le Beau
Publikováno v:
Cancer research. 62(12)
The FRA3B, at 3p14.2, lies within the fragile histidine triad (FHIT) gene and is the most highly expressed of the common fragile sites observed when DNA replication is perturbed by aphidicolin. Common fragile sites are highly unstable regions of the
Autor:
Rafael Espinosa, Michelle M. Le Beau, Thomas W. Glover, Feyruz V. Rassool, David I. Smith, Mary E. Neilly, Timothy W. McKeithan
Publikováno v:
Human molecular genetics. 7(4)
The FRA3B at 3p14.2 is the most highly expressed of the common fragile sites observed when DNA replication is perturbed by aphidicolin or folate stress. The molecular basis for chromosome fragility at FRA3B is unknown. In contrast to the rare fragile
Autor:
Timothy W. McKeithan, Feyruz V. Rassool, Mei-Ling Shen, Mary E. Neilly, Ferenc Boldog, Robert M. McCarroll, Rafael Espinosa, S. Tiong Ong, Harry A. Drabkin, Michelle M. Le Beau
Publikováno v:
Genomics. 35(1)
Despite several lines of evidence suggesting that common chromosomal fragile sites are biologically important as hot spots for recombination, their structure remains unknown. We showed previously that the plasmid pSV2neo preferentially integrates int
Autor:
Timothy W. McKeithan, Feyruz V. Rassool, R. Espinosa, Mary E. Neilly, M M Le Beau, E van Melle
Fragile sites are specific regions of chromosomes that are prone to breakage. In cells cultured under conditions that induce fragile site expression, high levels of inter- and intrachromosomal recombination have been observed involving chromosomal ba
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::818ece8beff3608646fb18768e959d82
https://europepmc.org/articles/PMC52147/
https://europepmc.org/articles/PMC52147/
Publikováno v:
Europe PubMed Central
Comparative gene mapping analysis in mammals suggests that the major histocompatibility complex (MHC) genes map syntenic with genes, such as glyoxylase 1 (GLO1). In man, the MHC locus and other genes of this syntenic group map to chromosome band 6p21