Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Mary E. Link"'
Autor:
Mary E. Link, Matthew M. Hsieh, John F. Tisdale, Katherine Roskom, Wynona Coles, Stefan Cordes, Tiffani Taylor, Courtney D. Fitzhugh
Publikováno v:
Blood. 130:1946-1948
Novel curative therapies using genetic transfer of normal globin-producing genes into autologous hematopoietic stem cells (HSCs) are in clinical trials for patients with sickle cell disease (SCD). The percentage of transferred globin necessary to cur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e71cf35cb95b9f928f9345522c0b18c4
https://doi.org/10.1182/blood-2017-03-772392
https://doi.org/10.1182/blood-2017-03-772392
Publikováno v:
Blood Cells Mol Dis
BACKGROUND: Benign ethnic neutropenia (BEN), defined by neutrophil count less than 1·5 k/uL in the absence of other causes, is an asymptomatic condition more commonly observed in individuals of African ancestry. However, the natural history of this
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1ea1b0b8719a3a9666d5b831882dc77
https://doi.org/10.2139/ssrn.3307704
https://doi.org/10.2139/ssrn.3307704
Autor:
Terri H. Wakefield, Eric R. Henry, William A. Eaton, Jeffrey F. Smith, Matthew M. Hsieh, Mary E. Link, Emily B. Dunkelberger, Jeffery L. Miller, James Hofrichter, Troy Cellmer, John F. Tisdale, Dwayne Staton, Belhu B. Metaferia, Garrott W. Christoph, Stacy Jones-Straehle, Quan Li, Sarah Boutom, Erica R. Vass
Publikováno v:
Proceedings of the National Academy of Sciences. 114
Although it has been known for more than 60 years that the cause of sickle cell disease is polymerization of a hemoglobin mutant, hydroxyurea is the only drug approved for treatment by the US Food and Drug Administration. This drug, however, is only
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5594850c3d4be6142aecdb666e07fc70
https://doi.org/10.1073/pnas.1619054114
https://doi.org/10.1073/pnas.1619054114
Autor:
John F. Tisdale, Matthew M. Hsieh, Nicola M. Neary, Courtney D. Fitzhugh, Helen Gharwan, Richard J. Sherins, Mary E. Link
Publikováno v:
Endocrine Practice. 20:e157-e161
Objective Myeloablative conditioning regimens given prior to hematopoietic stem cell transplantation (HSCT) frequently cause permanent sterility in men. In patients with sickle cell disease (SCD) we use a nonmyeloablative regimen with sirolimus, alem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5313c8cdc83f6d3eecc2b480b97e31f9
https://doi.org/10.4158/ep13474.cr
https://doi.org/10.4158/ep13474.cr
Autor:
Alexis Leonard, Aylin C. Bonifacino, Francis J. Pierciey, Anna Conrey, Naoya Uchida, Venina Marcela Dominical, John F. Tisdale, Mary E. Link, Wynona Coles, Min Luo, Matthew M. Hsieh
Publikováno v:
Blood. 130:966-966
Introduction Gene therapy for sickle cell disease (SCD) requires modification of a high number of long term engrafting hematopoietic stem cells (LT-HSCs) sufficient to sustain production of the gene of interest at levels capable of overcoming the pat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0bdb917253e26cd3a0efeb977dec2510
https://doi.org/10.1182/blood.v130.suppl_1.966.966
https://doi.org/10.1182/blood.v130.suppl_1.966.966
Autor:
Elizabeth J. Read, Griffin P. Rodgers, Susan F. Leitman, Virginia David-Ocampo, John F. Tisdale, Mary E. Link, Courtney D. Fitzhugh, Elizabeth M. Kang, Ellen M. Areman
Publikováno v:
Blood. 99:850-855
Mobilized peripheral blood is increasingly used as the source of hematopoietic stem cells for allogeneic transplantation, currently the only curative approach for sickle cell anemia. However, the safety and feasibility of stem cell mobilization in in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7385af6765cc5e50d43c103e9251150
https://doi.org/10.1182/blood.v99.3.850
https://doi.org/10.1182/blood.v99.3.850
Autor:
John F. Tisdale, Wynona Coles, R. Patrick Weitzel, Jonathan D. Powell, Matthew M. Hsieh, Mary E. Link, Xiongce Zhao, Griffin P. Rodgers, Courtney D. Fitzhugh
Publikováno v:
JAMA. 312(1)
Importance Myeloablative allogeneic hematopoietic stem cell transplantation (HSCT) is curative for children with severe sickle cell disease, but toxicity may be prohibitive for adults. Nonmyeloablative transplantation has been attempted with degrees
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab80fc8d052bd3db2a937186363d5593
https://pubmed.ncbi.nlm.nih.gov/25058214
https://pubmed.ncbi.nlm.nih.gov/25058214
Autor:
Eugene Park, Mary E. Link, Jay N. Lozier, Chutima Kumkhaek, Tiffani Taylor, John F. Tisdale, Matthew M. Hsieh, Wynona Coles
Publikováno v:
Blood. 128:3842-3842
We have reported a case of acquired hemophilia A in our series of sickle cell disease patients treated with hematopoietic stem cell transplantation (HSCT) using HLA matched sibling donors, non-myeloablative conditioning, and sirolimus immunosuppressi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c8f35c0151d1f633fab621fb70bbc3f2
https://doi.org/10.1182/blood.v128.22.3842.3842
https://doi.org/10.1182/blood.v128.22.3842.3842
Publikováno v:
Clinical Nursing Research. 9:479-491
The purpose of this study was to compare two lying and standing procedures for measuring orthostatic vital signs. Thirty-five normotensive participants (mean age 21.6 years) participated in a randomized crossover study. Measures of blood pressure (BP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::267760bc01eea5c27472cd376e982614
https://doi.org/10.1177/10547730022158708
https://doi.org/10.1177/10547730022158708
Autor:
Wynona Coles, John F. Tisdale, Vincent Hathaway, Courtney D. Fitzhugh, Hayato Unno, Xiongce Zhao, Mary E. Link, Elizabeth C. Wright, David F. Stroncek, Gregory J. Kato, Matthew M. Hsieh, R. Patrick Weitzel
Peripheral blood stem cell (PBSC) infusions are associated with complications such as elevated blood pressure and decreased creatinine clearance. Patients with sickle cell disease experience similar manifestations, and some have postulated release of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5eb1cc4854d84db07e29c416a0e39614
https://europepmc.org/articles/PMC3382927/
https://europepmc.org/articles/PMC3382927/
