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pro vyhledávání: '"Mary E. Kolell"'
Autor:
Samantha K. Swift, Alexandra L. Purdy, Mary E. Kolell, Kaitlyn G. Andresen, Caitlin Lahue, Tyler Buddell, Kaelin A. Akins, Christoph D. Rau, Caitlin C. O'Meara, Michaela Patterson
Publikováno v:
Development. 150
Somatic polyploidization, an adaptation by which cells increase their DNA content to support growth, is observed in many cell types, including cardiomyocytes. Although polyploidization is believed to be beneficial, progression to a polyploid state is
Autor:
Samantha K. Swift, Alexandra L. Purdy, Mary E. Kolell, Michael A. Flinn, Caitlin Lahue, Tyler Buddell, Kaelin A. Akins, Parker Foster, Caitlin C. O’Meara, Christoph D. Rau, Michaela Patterson
SUMMARYSomatic polyploidization, an adaptation by which cells increase their DNA content to support cell and organ growth, is observed in many mammalian cell types, including cardiomyocytes. Although polyploidization is beneficial in many contexts, p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7bbf20e2d42efe6eb9410967b81745b4
https://doi.org/10.1101/2022.09.15.508152
https://doi.org/10.1101/2022.09.15.508152
Autor:
Samantha K Swift, Mary E Kolell, Alexandra L Purdy, Michael A Flinn, Caitlin C O'Meara, Christoph D Rau, Michaela Patterson
Publikováno v:
Circulation Research. 131
Polyploidization is a normal cellular adaptation for a variety of cell types in mammals, including cardiomyocytes (CMs); however, the development of polyploidization understudied. Recent work suggests that genetics contribute to diverse displays of p
Autor:
Alexandra L Purdy, Mary E Kolell, Makenna Knas, Santiago Alvarez, Parker Foster, Melinda R Dwinell, Laura M Saba, Caitlin O'Meara, Michaela Patterson
Publikováno v:
Circulation Research. 131
Outcomes following cardiac injury are influenced by lifestyle and environment, as well as genetic background. Our interest lies in the latter, where very few genes have successfully been linked to heart failure. Contributors to this low success rate