Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Mary E Piper"'
Publikováno v:
PLoS ONE, Vol 6, Iss 3, p e18070 (2011)
The Rift Valley fever virus is responsible for periodic, explosive epizootics throughout sub-Saharan Africa. The development of therapeutics targeting this virus is difficult due to a limited understanding of the viral replicative cycle. Utilizing a
Externí odkaz:
https://doaj.org/article/9bbb2c8b037b4c07ad71fd55927a5a05
Autor:
Anushka Gupta, Tian Lian Huang, Yu-Hua Tseng, Farnaz Shamsi, Matthew D. Lynes, Mary E. Piper, Aaron M. Streets, Li-Lun Ho
Publikováno v:
Nature metabolism
Brown adipose tissue (BAT) and beige fat function in energy expenditure in part due to their role in thermoregulation, making these tissues attractive targets for treating obesity and metabolic disorders. While prolonged cold exposure promotes de nov
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a3cc3ebec76ee82d1ad751955cfa608
http://europepmc.org/articles/PMC8076094
http://europepmc.org/articles/PMC8076094
Autor:
Mary E. Piper, Sonja R. Gerrard
Publikováno v:
Viruses, Vol 2, Iss 3, Pp 731-747 (2010)
Rift Valley fever virus (RVFV) is a human and livestock pathogen endemic to sub-Saharan Africa. We have developed a T7-dependent system for the efficient production of RVFV-like particles (RVF-VLPs) based on the virulent ZH-501 strain of RVFV. The RV
Externí odkaz:
https://doaj.org/article/b103df144a5c4120991c00cd02f87e9c
Autor:
Sehgal R, Perez-Matos Mc, William B. Mair, Hannah J. Smith, Mutlu As, Meeta Mistry, Porsha R. Howell, Anne Lanjuin, Sneha Dutta, Meng C. Wang, Arpit Sharma, Mary E. Piper, Caroline Heintz
Geroscience aims to target the aging process to extend healthspan. However, even isogenic individuals show heterogeneity in natural aging rate and responsiveness to pro-longevity interventions, limiting translational potential. Using in vivo mini gen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8b91c2b30e545cde54ca5814f2ebef4f
https://doi.org/10.1101/2021.11.01.466772
https://doi.org/10.1101/2021.11.01.466772
Autor:
Parimal Rana, Michelle Chung, Sean K. Wang, Sophia Zhao, Emma R. West, Xuke Ji, Constance L. Cepko, Yunlu Xue, Hongbin Xu, Wenjun Xiong, Mary E. Piper, Maryna V. Ivanchenko, Marcelo Cicconet, David M. Wu
Publikováno v:
JCI Insight, Vol 6, Iss 2 (2021)
JCI Insight
JCI Insight
Nrf2, a transcription factor that regulates the response to oxidative stress, has been shown to rescue cone photoreceptors and slow vision loss in mouse models of retinal degeneration (rd). The retinal pigment epithelium (RPE) is damaged in these mod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e5108abd8f1dbb7703dd8082d25df86
https://doaj.org/article/66ed3b635a034060a47e1f54e323c711
https://doaj.org/article/66ed3b635a034060a47e1f54e323c711
Autor:
Carla F. Kim, Ryan M. Hekman, Benjamin C. Blum, William D. Wallace, Eileen Fung, Steven M. Dubinett, Roderick T. Bronson, Preetida J. Bhetariya, Sharon M. Louie, Carlos Villacorta-Martin, Antonella F.M. Dost, Andrew Emili, Jane Yanagawa, Julio Sainz de Aja, Dar Heinze, Marall Vedaie, Gustavo Mostoslavsky, Gregory A. Fishbein, Mary E. Piper, Julian H. Kwan, Samuel P. Rowbotham, Linh M. Tran, Kostyantyn Krysan, Jessie Huang, Aaron L. Moye, Darrell N. Kotton
Publikováno v:
Cell stem cell, vol 27, iss 4
Cell Stem Cell
Cell Stem Cell
Summary Mutant KRAS is a common driver in epithelial cancers. Nevertheless, molecular changes occurring early after activation of oncogenic KRAS in epithelial cells remain poorly understood. We compared transcriptional changes at single-cell resoluti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc7ee7e1f223f34dcae0593d2b9c2b20
https://escholarship.org/uc/item/59d4j07r
https://escholarship.org/uc/item/59d4j07r
Brown adipose tissue (BAT) functions in energy expenditure in part due its role in thermoregulation. The prominent capacity of BAT to enhance fuel utilization and energy expenditure makes it an attractive target for treating obesity and metabolic dis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e08524e4a52ec57d486eb17bbb08eb92
https://doi.org/10.1101/2020.06.26.174094
https://doi.org/10.1101/2020.06.26.174094
Publikováno v:
Diabetes. 69
Brown adipose tissue (BAT) is the major thermogenic organ, which promotes energy expenditure through a process called adaptive thermogenesis. Central to the inherent thermogenic activity of brown adipocytes is uncoupling protein 1(UCP1). Other than m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8c0314974115ce8ef3443b8b39c13283
https://doi.org/10.2337/db20-41-or
https://doi.org/10.2337/db20-41-or
Autor:
Suzanne E. Hickman, Emilia A. H. Vanni, Jay A. Fishman, Rosio Fernandez, Erik R. Abels, Joseph El Khoury, Yiming Yang, Han Chen, Miguel Velazquez-Palafox, Ian J. Taylor, Terry K. Means, Donald M. Coen, Mary E. Piper, Fei Ji, Eric S. Rosenberg, Rebekah J. Lane, Ruslan I. Sadreyev, Jean M. Pesola, Pritha Sen, Bo Li, Adrian R. Wilkie, Liza M. Morsett
Publikováno v:
Science Advances
CMV-infected monocytes are unable to phagocytose fungal pathogens yet produce inflammation associated with rejection and GVHD.
Cytomegalovirus (CMV) is an important cause of morbidity and mortality in the immunocompromised host. In transplant re
Cytomegalovirus (CMV) is an important cause of morbidity and mortality in the immunocompromised host. In transplant re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e03af9cfdf3ce2b711540fb95db50d3f
https://doi.org/10.1126/sciadv.aax9856
https://doi.org/10.1126/sciadv.aax9856
Autor:
Alan L Jiao, David Pellman, Jeffrey R. Haswell, Mary E. Piper, Roberto Perales, Frank J. Slack, Neil T. Umbreit, Scott Kennedy, Brian D. Adams
Publikováno v:
RNA. 25:352-363
The accurate inheritance of genetic material is a basic necessity in all domains of life and an unexpectedly large number of RNA processing factors are required for mitotic progression and genome stability. NRDE2 (nuclear RNAi defective-2) is an evol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bc47b1fd7e22916abd02ed1bfb9c7fb
https://doi.org/10.1261/rna.069773.118
https://doi.org/10.1261/rna.069773.118