Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Mary E Ballestas"'
Autor:
Harish Chandra Pal, Samriti Sharma, Leah Ray Strickland, Santosh K Katiyar, Mary E Ballestas, Mohammad Athar, Craig A Elmets, Farrukh Afaq
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e86338 (2014)
Malignant melanoma is responsible for approximately 75% of skin cancer-related deaths. BRAF plays an important role in regulating the mitogen-activated protein kinase (MAPK) signaling cascade in melanoma with activating mutations in the serine/threon
Externí odkaz:
https://doaj.org/article/9f05bec9c95d426da2742364f34c0b66
Publikováno v:
PLoS ONE, Vol 7, Iss 6, p e39586 (2012)
Endoplasmic reticulum (ER) stress-induced apoptosis has been implicated in various neurodegenerative diseases including Parkinson Disease, Alzheimer Disease and Huntington Disease. PUMA (p53 upregulated modulator of apoptosis) and BIM (BCL2 interacti
Externí odkaz:
https://doaj.org/article/d895311440ae4735a8aee2498efcbeee
Autor:
Mary E. Ballestas, Sooryanarayana Varambally, Suman Karki, Richard Kirkman, Anirban Kundu, Sejong Bae, Arindam P. Ghosh, Sunil Sudarshan, Sandeep B. Shelar, Hyeyoung Nam, Garrett J. Brinkley, James A. Mobley
Publikováno v:
J Biol Chem
Ten-eleven translocation-2 (TET2) is a member of the methylcytosine dioxygenase family of enzymes and has been implicated in cancer and aging because of its role as a global epigenetic modifier. TET2 has a large N-terminal domain and a catalytic C-te
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57d44986a95b83689e98d14e46450491
https://doi.org/10.1074/jbc.ra119.011089
https://doi.org/10.1074/jbc.ra119.011089
Autor:
Samuel S. McCachren, Julia Manalo, Katherine Pendleton, Mary E. Ballestas, Kavita M. Dhodapkar, Melissa L. Kemp, Max D. Cooper, Madhav V. Dhodapkar
Publikováno v:
Cancer Research. 82:580-580
Novel strategies to target tumors are needed to enhance the efficacy of immune redirection therapies. The detection of tumors based on mammalian immunoglobulin scFvs has been a significant innovation in immunotherapy but is impacted by limits of immu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6cc322064998073314ce753ff15d8a5a
https://doi.org/10.1158/1538-7445.am2022-580
https://doi.org/10.1158/1538-7445.am2022-580
Autor:
Evida A. Dennis, Lesley E. Smythies, Richard Stahl, Michael Niederweis, Phillip D. Smith, Jayleen Grams, Jim Sun, William J. Britt, Mary E. Ballestas, Robert Grabski, Masako Shimamura, Mao Li
Publikováno v:
Mucosal immunology
Intestinal macrophages in healthy human mucosa are profoundly down-regulated for inflammatory responses (inflammation anergy) due to stromal TGF-β inactivation of NF-κB. Paradoxically, in cytomegalovirus (CMV) intestinal inflammatory disease, one o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6687e4a20006092be88096697bfdb527
https://doi.org/10.1038/s41385-018-0041-4
https://doi.org/10.1038/s41385-018-0041-4
Autor:
Mitsuhiko Ikura, Mary E. Ballestas, Christopher B. Marshall, Tatjana Coric, Richard Kirkman, Mary-Ann Bjornsti, Sunil Sudarshan, Arindam P. Ghosh, Eun-Hee Shim
Publikováno v:
Oncotarget
Aberrations in the mTOR (mechanistic target of rapamycin) axis are frequently reported in cancer. Using publicly available tumor genome sequencing data, we identified several point mutations in MTOR and its upstream regulator RHEB (Ras homolog enrich
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::657998a3fb78d34de83a149ada201733
https://doi.org/10.18632/oncotarget.4963
https://doi.org/10.18632/oncotarget.4963
Autor:
Astha Maltare, Angela K. Nietz, Taylor S. Dunn, Ann M. Laszczyk, Mary Ann Accavitti-Loper, Mary E. Ballestas, Gwendalyn D. King
Publikováno v:
Monoclonal Antibodies in Immunodiagnosis and Immunotherapy. 33:420-427
Although antibodies are commercially available to allow investigation into the biology of the age-regulating protein Klotho, problems with antibody specificity and application functionality are significant barriers to progress. Chief among these limi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::164346e06fb6ef6dc4ba9e2685566eb2
https://doi.org/10.1089/mab.2014.0040
https://doi.org/10.1089/mab.2014.0040
Autor:
Mary E. Ballestas, Farah D. Lubin, Joshua L. Cohen, Nateka L. Jackson, Sarah M. Clinton, William M. Webb
Publikováno v:
The European journal of neuroscience. 46(7)
A greater understanding of neural mechanisms contributing to anxiety is needed in order to develop better therapeutic interventions. This study interrogates a novel molecular mechanism that shapes anxiety-like behaviour, demonstrating that the microR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6b654b2d790c375ca67937a03e33a62
https://pubmed.ncbi.nlm.nih.gov/28612962
https://pubmed.ncbi.nlm.nih.gov/28612962
Autor:
Jessy S. Deshane, Mohammad Athar, David R. Bickers, Mary E. Ballestas, David J. Robbins, Changzhao Li, Farrukh Afaq, Sadis Matalon, Craig A. Elmets, Sandeep C. Chaudhary, Ritesh K. Srivastava
Publikováno v:
Toxicology and Applied Pharmacology. 272:879-887
Arsenic exposure is known to disrupt innate immune functions in humans and in experimental animals. In this study, we provide a mechanism by which arsenic trioxide (ATO) disrupts macrophage functions. ATO treatment of murine macrophage cells diminish
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a477ce3cb37598e7849d1699bd0a37d0
https://doi.org/10.1016/j.taap.2013.08.004
https://doi.org/10.1016/j.taap.2013.08.004
Autor:
Richard D. Moore, Daniel R. Drozd, Mary E. Ballestas, Joseph J. Eron, Eric A. Engels, Anna E. Coghill, Elizabeth L. Yanik, Chad J. Achenbach, Ayad Hamdan, Satish Gopal, Stephen R. Cole, W. Christopher Mathews
Purpose The biology of HIV-associated cancers may differ depending on immunologic and virologic context during development. Therefore, an understanding of the burden of Kaposi's sarcoma (KS) and non-Hodgkin lymphoma (NHL) relative to antiretroviral t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84506eccec390f57c042978279768d6c
