Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Mary Dass"'
Autor:
Rahimeh Emamnejad, Mary Dass, Michael Mahlis, Salome Bozkurt, Sining Ye, Maurice Pagnin, Paschalis Theotokis, Nikolaos Grigoriadis, Steven Petratos
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Multiple sclerosis (MS) is a heterogeneous autoimmune disease whereby the pathological sequelae evolve from oligodendrocytes (OLs) within the central nervous system and are targeted by the immune system, which causes widespread white matter pathology
Externí odkaz:
https://doaj.org/article/16603ae7026e485798941b8717bb479e
Autor:
Olivia Ellen, Sining Ye, Danica Nheu, Mary Dass, Maurice Pagnin, Ezgi Ozturk, Paschalis Theotokis, Nikolaos Grigoriadis, Steven Petratos
Multiple sclerosis (MS) is a heterogeneous disease of the central nervous system that is governed by neural tissue loss and dystrophy during its progressive phase, with complex reactive pathological cellular changes. The immune-mediated mechanisms th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::29d4b15f59ff13d08e4c0ae25aeca5a4
https://doi.org/10.20944/preprints202305.1549.v1
https://doi.org/10.20944/preprints202305.1549.v1
Autor:
Prasanna Bhat, Vasilisa Aksenova, Matthew Gazzara, Emily A. Rex, Sadaf Aslam, Christina Haddad, Shengyan Gao, Matthew Esparza, Tolga Cagatay, Kimberly Batten, Sara S. El Zahed, Alexei Arnaoutov, Hualin Zhong, Jerry W. Shay, Blanton S. Tolbert, Mary Dasso, Kristen W. Lynch, Adolfo García-Sastre, Beatriz M. A. Fontoura
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Abstract Nuclear export of influenza A virus (IAV) mRNAs occurs through the nuclear pore complex (NPC). Using the Auxin-Induced Degron (AID) system to rapidly degrade proteins, we show that among the nucleoporins localized at the nucleoplasmic side o
Externí odkaz:
https://doaj.org/article/ef526c85c77e4e78867cbdc75323343a
Autor:
Sanjana Sundararajan, Hyewon Park, Shinji Kawano, Marnie Johansson, Bunu Lama, Tomoko Saito-Fujita, Noriko Saitoh, Alexei Arnaoutov, Mary Dasso, Zhengqiang Wang, Daniel Keifenheim, Duncan J. Clarke, Yoshiaki Azuma
Publikováno v:
iScience, Vol 26, Iss 5, Pp 106743- (2023)
Summary: DNA Topoisomerase IIα (TopoIIα) decatenates sister chromatids, allowing their segregation in mitosis. Without the TopoIIα Strand Passage Reaction (SPR), chromosome bridges and ultra-fine DNA bridges (UFBs) arise in anaphase. The TopoIIα
Externí odkaz:
https://doaj.org/article/19bb8937fd674b67b4767f3d9fe007bf
Autor:
Vasilisa Aksenova, Alexandra Smith, Hangnoh Lee, Prasanna Bhat, Caroline Esnault, Shane Chen, James Iben, Ross Kaufhold, Ka Chun Yau, Carlos Echeverria, Beatriz Fontoura, Alexei Arnaoutov, Mary Dasso
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
mRNAs export from the nucleus is thought to be regulated in part by three nucleoporins that comprise the nuclear basket, but whether and how distinct basket nucleoporins interact with the RNA export machinery is unclear. Here, the authors use rapid a
Externí odkaz:
https://doaj.org/article/b11e933a22b94f5d92aa8aec90845e1b
Publikováno v:
Nucleus, Vol 10, Iss 1, Pp 216-220 (2019)
Wilhelm Bernhard’s revolutionary microscopy techniques helped him put forward the hypothesis of specialized compartmentalization of the nucleus. He also described for the first time the nuclear bodies and peri-chromatin fibrils, and demonstrated th
Externí odkaz:
https://doaj.org/article/960bcc2d39f34068a75eba65f4af5a2e
Autor:
Alexei Arnaoutov, Hangnoh Lee, Karen Plevock Haase, Vasilisa Aksenova, Michal Jarnik, Brian Oliver, Mihaela Serpe, Mary Dasso
Publikováno v:
iScience, Vol 23, Iss 3, Pp - (2020)
Summary: The maintenance of the intestinal epithelium is ensured by the controlled proliferation of intestinal stem cells (ISCs) and differentiation of their progeny into various cell types, including enterocytes (ECs) that both mediate nutrient abso
Externí odkaz:
https://doaj.org/article/50e282ba09e7455d8d5363967e08e1dd
Autor:
Xiao Ling Li, Murugan Subramanian, Matthew F. Jones, Ritu Chaudhary, Deepak K. Singh, Xinying Zong, Berkley Gryder, Sivasish Sindri, Min Mo, Aaron Schetter, Xinyu Wen, Swetha Parvathaneni, Dickran Kazandjian, Lisa M. Jenkins, Wei Tang, Fathi Elloumi, Jennifer L. Martindale, Maite Huarte, Yuelin Zhu, Ana I. Robles, Susan M. Frier, Frank Rigo, Maggie Cam, Stefan Ambs, Sudha Sharma, Curtis C. Harris, Mary Dasso, Kannanganattu V. Prasanth, Ashish Lal
Publikováno v:
Cell Reports, Vol 20, Iss 10, Pp 2408-2423 (2017)
Basal p53 levels are tightly suppressed under normal conditions. Disrupting this regulation results in elevated p53 levels to induce cell cycle arrest, apoptosis, and tumor suppression. Here, we report the suppression of basal p53 levels by a nuclear
Externí odkaz:
https://doaj.org/article/44875ca0858a47c68888951b9611cf2c
Publikováno v:
Cells, Vol 10, Iss 3, p 536 (2021)
Vertebrate postembryonic development is regulated by thyroid hormone (T3). Of particular interest is anuran metamorphosis, which offers several unique advantages for studying the role of T3 and its two nuclear receptor genes, TRα and TRβ, during po
Externí odkaz:
https://doaj.org/article/81fc8db4c15e4e4784cf5ba91e83cefa
Autor:
Ritu Chaudhary, Berkley Gryder, Wendy S Woods, Murugan Subramanian, Matthew F Jones, Xiao Ling Li, Lisa M Jenkins, Svetlana A Shabalina, Min Mo, Mary Dasso, Yuan Yang, Lalage M Wakefield, Yuelin Zhu, Susan M Frier, Branden S Moriarity, Kannanganattu V Prasanth, Pablo Perez-Pinera, Ashish Lal
Publikováno v:
eLife, Vol 6 (2017)
Thousands of long noncoding RNAs (lncRNAs) have been discovered, yet the function of the vast majority remains unclear. Here, we show that a p53-regulated lncRNA which we named PINCR (p53-induced noncoding RNA), is induced ~100-fold after DNA damage
Externí odkaz:
https://doaj.org/article/0e4efcf121494f7b9aa2a822c1a3169e