Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Mary Crossman"'
Autor:
Joleen T. White, Scott D. Newsome, Bernd C. Kieseier, Robert A. Bermel, Yue Cui, Ali Seddighzadeh, Serena Hung, Mary Crossman, Meena Subramanyam
Publikováno v:
Therapeutic Advances in Neurological Disorders, Vol 9 (2016)
Background: Efficacy of interferon beta in multiple sclerosis (MS) can be dampened in patients who develop neutralizing antidrug antibodies (NAbs). Peginterferon beta1a is an interferon conjugated with a polyethylene glycol (PEG) moiety. Pegylation i
Externí odkaz:
https://doaj.org/article/218894cfb2cd433b9f87df69b742ddd1
Autor:
Ali Seddighzadeh, Joleen T. White, Serena Hung, Bernd C. Kieseier, Mary Crossman, Robert A. Bermel, Meena Subramanyam, Yue Cui, Scott D. Newsome
Publikováno v:
Therapeutic Advances in Neurological Disorders, Vol 9 (2016)
Background: Efficacy of interferon beta in multiple sclerosis (MS) can be dampened in patients who develop neutralizing antidrug antibodies (NAbs). Peginterferon beta1a is an interferon conjugated with a polyethylene glycol (PEG) moiety. Pegylation i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c3a912ead08bb6f9cf94ae5575b4402
https://doaj.org/article/218894cfb2cd433b9f87df69b742ddd1
https://doaj.org/article/218894cfb2cd433b9f87df69b742ddd1
Multi-site analytical validation of an assay to detect anti-JCV antibodies in human serum and plasma
Autor:
Brian Schlain, Moses Njenga, Meena Subramanyam, Melissa Berman, Mary Crossman, Leonid Gorelik, Michaela Lerner, Tatiana Plavina, Kenneth Simon
Publikováno v:
Journal of Clinical Virology. 53:65-71
Background JC virus (JCV) infection is a prerequisite for development of progressive multifocal leukoencephalopathy (PML). We previously described the development of a novel, two-step enzyme-linked immunosorbent assay (ELISA) that detects anti-JCV an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f8e2be33030c29935ba852e5a5840a6
https://doi.org/10.1016/j.jcv.2011.10.003
https://doi.org/10.1016/j.jcv.2011.10.003
Autor:
Michaela Lerner, Margot Brickelmaier, Mary Crossman, Darren P. Baker, Ivan Nestorov, Shifang Liu, Meena Subramanyam, Larisa Miller, Gudarz Davar, Michael Panzara, R. B. Pepinsky, Xiao Hu, Ying Zhu, Sandra Richman, Kenneth Olivier, Gabrielle Glick, Stacy Hitchman, Robert S. Gronke
Publikováno v:
Journal of Interferon & Cytokine Research. 30:777-785
Multiple sclerosis is a chronic autoimmune disease of the central nervous system for which a number of disease-modifying therapies are available, including interferon beta (Avonex®, Rebif®, and Betaseron/Betaferon®), glatiramer acetate (Copaxone®
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14f53fa804911001fcd6d81ce1f833f9
https://doi.org/10.1089/jir.2010.0092
https://doi.org/10.1089/jir.2010.0092
Publikováno v:
Bioanalysis. 7(21)
Aims: Neutralizing antibodies can diminish clinical efficacy of IFN-β in multiple sclerosis patients. Therefore, monitoring immunogenicity was considered critical during clinical development of a second-generation, pegylated IFN-β product, PEG-IFN-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9ea896aa8b7ae21a648063eced1ae63
https://pubmed.ncbi.nlm.nih.gov/26541956
https://pubmed.ncbi.nlm.nih.gov/26541956
Publikováno v:
Bioanalysis. 7(11)
Joleen White is Principal Scientist in Translational Sciences at Biogen Idec. Throughout her career, she has applied her background in biophysical protein chemistry to pharmaceutical development in therapeutic indications with significant unmet medic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49de36649248849af05d31ccbae94adc
https://pubmed.ncbi.nlm.nih.gov/26110707
https://pubmed.ncbi.nlm.nih.gov/26110707
Autor:
Evelyne Polack, Kenneth Olivier, Xiao Hu, Ivan Nestorov, Meena Subramanyam, Suezanne Parker, Mary Crossman, Darren P. Baker, Robert S. Gronke, Zhaoyang Li, Janet Clarke, Kathleen J. Zokowski
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 338(3)
Human interferon (IFN) β has well established beneficial effects in treating relapsing forms of multiple sclerosis, but current first-line treatment requires frequent (from daily to weekly) parenteral administration. A 20-kDa polyethylene glycol (PE
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30d54355bdcf32a66b466fd7dac3cbb0
https://pubmed.ncbi.nlm.nih.gov/21690216
https://pubmed.ncbi.nlm.nih.gov/21690216
Autor:
Robert S. Gronke, Xiao Hu, Mary Crossman, Ivan Nestorov, Shifang Liu, Stacy Hitchman, Ying Zhu, Larisa Miller, Mark Rogge, Sandra Richman, Meena Subramanyam, Gabrielle Glick, Gudarz Davar, Darren P. Baker
This study clinically evaluated a novel PEGylated form of interferon beta-1a (PEG-IFN beta-1a), a potential first-line treatment for relapsing multiple sclerosis, in healthy volunteers. Two randomized, blinded phase I studies were conducted: a single
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3920079ffe96ab946fdc0aa66b72375
https://www.bib.irb.hr/510550
https://www.bib.irb.hr/510550
Autor:
Leonid, Gorelik, Michaela, Lerner, Sarah, Bixler, Mary, Crossman, Brian, Schlain, Kenneth, Simon, Amy, Pace, Anne, Cheung, Ling Ling, Chen, Melissa, Berman, Fairuz, Zein, Ewa, Wilson, Ted, Yednock, Alfred, Sandrock, Susan E, Goelz, Meena, Subramanyam
Publikováno v:
Annals of neurology. 68(3)
A study was undertaken to establish an enzyme-linked immunosorbent assay (ELISA) to detect JC virus (JCV)-specific antibodies in multiple sclerosis (MS) patients, and to evaluate its potential utility for identifying patients at higher or lower risk
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::bee96be99e0b1f003ffb0d3b2d6e22ba
https://pubmed.ncbi.nlm.nih.gov/22926862
https://pubmed.ncbi.nlm.nih.gov/22926862
Autor:
Darren P. Baker, Robert Blake Pepinsky, Margot Brickelmaier, Robert S. Gronke, Xiao Hu, Kenneth Olivier, Michaela Lerner, Larisa Miller, Mary Crossman, Ivan Nestorov, Meena Subramanyam, Stacy Hitchman, Gabrielle Glick, Sandra Richman, Shifang Liu, Ying Zhu, Michael A. Panzara, Gudarz Davar
Publikováno v:
Journal of Interferon & Cytokine Research; Oct2010, Vol. 30 Issue 10, p777-785, 9p