Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Mary Coolbaugh-Murphy"'
Autor:
Daphnie Austria, Zane Best, Nohely Delgado, Giovanna De Vita, Alexis German, Katherine Le, Kimberly Krumwiede Hoggatt, Mary Coolbaugh-Murphy, Denise Juroske Short
Publikováno v:
Research Methods Poster Sessions.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::91f97263d25d3539ffa3d82bb9f61d5f
https://doi.org/10.52519/00111
https://doi.org/10.52519/00111
Autor:
Brian C. Ramagli, Louis S. Ramagli, Barry W. Brown, Patrick M. Lynch, Mary Coolbaugh-Murphy, Marsha L. Frazier, Jing Ping Xu, Stanley R. Hamilton, Michael J. Siciliano
Publikováno v:
Human Mutation. 31:317-324
Most hereditary nonpolyposis colorectal cancer (HNPCC) patients inherit a defective allele of a mismatch repair (MMR) gene, usually MLH1 or MSH2, resulting in high levels of microsatellite instability (MSI-H) in the tumors. Presence of MSI in the nor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::935609741220361144dd58967fe6a5dd
https://doi.org/10.1002/humu.21190
https://doi.org/10.1002/humu.21190
Publikováno v:
Current Colorectal Cancer Reports. 3:185-190
The contributions and limitations of the traditional method for evaluating microsatellite instability by standard polymerase chain reaction (PCR) in identifying mismatch repair (MMR) gene mutations in the Lynch syndrome form of hereditary nonpolyposi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::79395a274d3c625ef06b8c67de887a9b
https://doi.org/10.1007/s11888-007-0029-z
https://doi.org/10.1007/s11888-007-0029-z
Publikováno v:
Mechanisms of Ageing and Development. 126:1051-1059
Small pool PCR (SP-PCR) is a sensitive method for the detection and quantification of microsatellite instability (MSI) in somatic cells. Here we propose that mutant microsatellite fragments accumulate with age in normal somatic cells and that this in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43150e6ffe0a9822b64ac5b8624ab1e2
https://doi.org/10.1016/j.mad.2005.06.005
https://doi.org/10.1016/j.mad.2005.06.005
Autor:
Mary Coolbaugh-Murphy, Benjamin Lichtiger, Darren G. Monckton, Michael J. Siciliano, Marsha L. Frazier, Atousa Maleki, Barry W. Brown, Lou Ramagli
Publikováno v:
Genomics. 84:419-430
Identifying microsatellite instability (MSI) by partitioning DNA into multiple small pools containing only single genome amounts of DNA results in trapping both progenitor and low-frequency mutant alleles into pools where they can be identified and c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c6d1d3c721fe11f25150c7767c5a782
https://doi.org/10.1016/j.ygeno.2004.03.007
https://doi.org/10.1016/j.ygeno.2004.03.007
Autor:
Peter, Hu, Chang Woo, Lee, Jing P, Xu, Crystal, Simien, Chuan Li, Fan, Michael, Tam, Louis, Ramagli, Barry W, Brown, Patrick, Lynch, Marsha L, Frazier, Michael J, Siciliano, Mary, Coolbaugh-Murphy
Publikováno v:
Annals of clinical and laboratory science. 41(4)
Microsatellites are short tandem repeats of deoxyribonucleic acid (DNA) sequences which are distributed throughout the genome. Tumors in patients with Lynch syndrome tend to accumulate mutations in microsatellites at a much higher rate than other seq
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ef00d387db444997f35849101eb73f33
https://pubmed.ncbi.nlm.nih.gov/22166501
https://pubmed.ncbi.nlm.nih.gov/22166501